KEGG   Macaca fascicularis (crab-eating macaque): 101926249
Entry
101926249         CDS       T02918                                 
Symbol
HMGCR
Name
(RefSeq) 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X1
  KO
K00021  hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf00900  Terpenoid backbone biosynthesis
mcf01100  Metabolic pathways
mcf04152  AMPK signaling pathway
mcf04976  Bile secretion
Module
mcf_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    101926249 (HMGCR)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    101926249 (HMGCR)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    101926249 (HMGCR)
Enzymes [BR:mcf01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.34  hydroxymethylglutaryl-CoA reductase (NADPH)
     101926249 (HMGCR)
SSDB
Motif
Pfam: HMG-CoA_red Sterol-sensing Patched
Other DBs
NCBI-GeneID: 101926249
NCBI-ProteinID: XP_005557233
Ensembl: ENSMFAG00000036118
UniProt: A0A7N9CZC6
Position
6:70726093..70752100
AA seq 908 aa
MQWMSYTRQRDAGSTDSVSTMLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGN
NKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTI
FSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARG
MAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVL
ELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQ
NSTADTSKVSLGLDENVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFE
QAETESTLSLKNPITSPVVTQKKVPDNCCRREPVLVRNNQKCDSTEEETGINRERKVEVI
KPLVAETDTPNKATFVVGNASLLDTSSVLVTQEPEIELPGEPRPNEECLQILGNAEKGAK
FLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYS
LVMGACCENVIGYMPIPVGVAGPLCLDGKEFQVPMATTEGCLVASTNRGCRAIGLGGGAS
SRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAG
RNLYIRFQSRSGDAMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIE
GRGKSVVCEAVIPAKVVREVLKTTTDAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAI
YIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQM
LGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQ
GACTKKTA
NT seq 2727 nt   +upstreamnt  +downstreamnt
atgcaatggatgtcctacacgagacagagagatgcaggatccacggattctgtatctaca
atgttgtcaagactttttcgaatgcatggcctcttcgtggcctcccatccctgggaagtc
atagtgggaacagtgacattgaccatctgcatgatgtccatgaacatgtttactggtaac
aataagatctgtggttggaattatgaatgtccaaagtttgaagaggatgttttgagcagt
gacattataattctgacaataacacgatgcatagcaatcctgtatatttacttccagttc
cagaatttacgtcaacttggatcaaaatacattttgggtattgctggcctcttcacaatt
ttctcaagctttgtattcagtacagttgtcattcacttcttagacaaagaattgacaggc
ttgaatgaagctttgccctttttcctacttctgattgacctttccagagcaagtgcatta
gcaaagtttgccctcagttccaactcacaggatgaagtaagggaaaatattgctcgtgga
atggcaattttaggtccaacgtttaccctcgatgctcttgttgaatgtcttgtgattgga
gttggtaccatgtcaggggttcgtcagcttgaaattatgtgctgctttggctgcatgtca
gttcttgccaactacttcgtgttcatgactttcttcccagcttgtgtgtccttggtatta
gagctttctcgggaaagccgcgagggtcgtccaatttggcagctcagccattttgcccga
gttttagaagaagaagaaaataagccaaatcctgtaactcagagggtcaagatgattatg
tctctaggcttggttcttgttcatgctcacagtcgctggatagctgatccttctcctcaa
aacagtacagcagatacttctaaggtttctttaggactggatgaaaatgtgtctaagaga
attgaaccaagtgtttccctctggcaattttatctctctaaaatgatcagcatggatatt
gaacaagttattaccctaagtttagctctccttctggctgtcaagtacatcttctttgaa
caagcagagacagaatctacactctcgttaaaaaaccctatcacatctcctgtagtgaca
caaaagaaagtcccagacaactgttgtagacgtgaacctgtgctggtcagaaataaccag
aagtgtgattcaacagaggaagagacagggataaaccgagaaagaaaagttgaggttata
aaacccttagtggctgaaacagataccccaaacaaagctacatttgtggttggtaacgcc
tccttactcgatacttcgtcagtactggtgacacaggaacctgaaattgagcttcccggg
gaacctcggcctaacgaagaatgtctgcagatacttgggaatgcagagaaaggtgcaaaa
ttccttagtgatgctgagatcatccagttagtcaatgctaagcatatcccagcctacaag
ttggaaactctgatggaaactcatgagcgtggtgtatctattcgcagacagttactttcc
aaaaagctttcagaaccttcttctctccagtacctaccttacagggattataattactcc
ttggtgatgggagcttgttgtgagaatgttattggatatatgcccatccctgttggagta
gcaggacccctttgcttggatggaaaagaatttcaggttccaatggcaacaacagaaggt
tgtcttgtggccagcaccaatagaggctgcagagcaataggtcttggtggaggtgccagc
agccgagtccttgcagatgggatgactcgtggcccagttgtgcgtcttccacgtgcttgt
gactctgcagaagtgaaagcctggctcgaaacatctgaagggttcgcagtgataaaggag
gcatttgacagcactagcagatttgcacgtctacagaaacttcatacaagtatagctgga
cgcaacctttatatccgtttccagtccaggtcaggggatgccatggggatgaacatgatt
tcaaagggtacagagaaagcactttcaaaacttcatgagtatttccctgaaatgcagatt
ctagctgttagtggtaactattgtactgacaagaaacctgctgctataaactggatagag
ggaagaggaaaatctgttgtttgtgaagctgtcattccagccaaggttgtcagagaagta
ttaaagactaccacagacgctatgattgaggtcaacattaacaagaatttagtgggctct
gccatggctgggagcataggaggctacaacgcccatgcagcaaacattgtcactgccatc
tacattgcctgtggacaggatgcagcacagaatgttggtagttcaaactgtattacttta
atggaagcaagtggccccacaaatgaagatttatatatcagctgcaccatgccatctata
gagataggaacggtgggcggtgggaccaacctgctacctcagcaagcctgtttgcagatg
ctaggtgttcaaggagcatgcaaagataatcctggggaaaatgcccggcagcttgcccga
attgtgtgcgggaccgtaatggctggggaattgtcacttatggcagcattggcagcagga
catcttgtcaaaagtcatatgattcacaacaggtcgaagatcaatttacaagacctccaa
ggagcttgcactaagaagacagcttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (4)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (6)   
   RefSeq(nuc) (4)   
   GenBank (1)   
   EMBL (1)   
Protein domain (3)   
   Pfam (3)   
All databases (36)   

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