KEGG   Macaca fascicularis (crab-eating macaque): 102143464Help
Entry
102143464         CDS       T02918                                 

Gene name
PIK3CD
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:mcf00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102143464 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102143464 (PIK3CD)
   04015 Rap1 signaling pathway
    102143464 (PIK3CD)
   04012 ErbB signaling pathway
    102143464 (PIK3CD)
   04370 VEGF signaling pathway
    102143464 (PIK3CD)
   04630 Jak-STAT signaling pathway
    102143464 (PIK3CD)
   04668 TNF signaling pathway
    102143464 (PIK3CD)
   04066 HIF-1 signaling pathway
    102143464 (PIK3CD)
   04068 FoxO signaling pathway
    102143464 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    102143464 (PIK3CD)
   04024 cAMP signaling pathway
    102143464 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    102143464 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    102143464 (PIK3CD)
   04152 AMPK signaling pathway
    102143464 (PIK3CD)
   04150 mTOR signaling pathway
    102143464 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102143464 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    102143464 (PIK3CD)
  Cellular commiunity
   04510 Focal adhesion
    102143464 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    102143464 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102143464 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    102143464 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    102143464 (PIK3CD)
   04660 T cell receptor signaling pathway
    102143464 (PIK3CD)
   04662 B cell receptor signaling pathway
    102143464 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    102143464 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    102143464 (PIK3CD)
   04670 Leukocyte transendothelial migration
    102143464 (PIK3CD)
   04062 Chemokine signaling pathway
    102143464 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    102143464 (PIK3CD)
   04915 Estrogen signaling pathway
    102143464 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    102143464 (PIK3CD)
   04917 Prolactin signaling pathway
    102143464 (PIK3CD)
   04921 Oxytocin signaling pathway
    102143464 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    102143464 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102143464 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102143464 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102143464 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    102143464 (PIK3CD)
   04722 Neurotrophin signaling pathway
    102143464 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102143464 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    102143464 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102143464 (PIK3CD)
   05230 Central carbon metabolism in cancer
    102143464 (PIK3CD)
   05231 Choline metabolism in cancer
    102143464 (PIK3CD)
   05205 Proteoglycans in cancer
    102143464 (PIK3CD)
   05203 Viral carcinogenesis
    102143464 (PIK3CD)
   05210 Colorectal cancer
    102143464 (PIK3CD)
   05212 Pancreatic cancer
    102143464 (PIK3CD)
   05214 Glioma
    102143464 (PIK3CD)
   05221 Acute myeloid leukemia
    102143464 (PIK3CD)
   05220 Chronic myeloid leukemia
    102143464 (PIK3CD)
   05218 Melanoma
    102143464 (PIK3CD)
   05211 Renal cell carcinoma
    102143464 (PIK3CD)
   05215 Prostate cancer
    102143464 (PIK3CD)
   05213 Endometrial cancer
    102143464 (PIK3CD)
   05222 Small cell lung cancer
    102143464 (PIK3CD)
   05223 Non-small cell lung cancer
    102143464 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102143464 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102143464 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102143464 (PIK3CD)
   05166 HTLV-I infection
    102143464 (PIK3CD)
   05162 Measles
    102143464 (PIK3CD)
   05164 Influenza A
    102143464 (PIK3CD)
   05161 Hepatitis B
    102143464 (PIK3CD)
   05160 Hepatitis C
    102143464 (PIK3CD)
   05169 Epstein-Barr virus infection
    102143464 (PIK3CD)
   05146 Amoebiasis
    102143464 (PIK3CD)
   05145 Toxoplasmosis
    102143464 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    102143464 (PIK3CD)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102143464 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
1
AA seq 1068 aa AA seqDB search
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARTWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQVQKPRAKPPPIPAKKPFSVSLWSLEQPFCIELIQGSKVNA
DERMKLVVQAGLFHGNEMLCKTVSSSEVSVCSEPVWKQRLEFDIHICDLPRMARLCFALY
AVIEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNP
TGTVRSNPNTDSAAALLICLPEVAPHPVYYPALEKLLGGMVLASRGWRPELLWICLHARD
SAPSRMIGVATPCLGVLPGLFQALGDAECSCLLQILELGRHSECVHVTEEEQLQLREILE
RRGSGELYEHEKDLVWKLRHEVQEHFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPV
LSALELLDFSFPDCHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDR
ALANRKIGHFLFWHLRSEMHVPSVALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALN
DFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKM
KPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCL
PTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFT
LSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTY
DFVHVIQQGKTNNSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQ
YLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
NT seq 3207 nt NT seq  +upstreamnt  +downstreamnt
atgccccctggggtggactgccccatggaattctggaccaaggaggagaatcagagcgtc
gtggttgacttcctgctgcccacaggggtctacctgaacttccctgtgtcccgcaatgcc
aacctcagcaccatcaagcagctgctgtggcaccgcgcccagtatgagccactcttccac
atgctcagtggccccgaggcctatgtgttcacctgcatcaaccagacggcggagcagcag
gagctggaggatgagcaacggcgtctgtgcgacgtgcagcccttcctgcccgtcctgcgc
ctggtggcccgcgagggcgaccgcgtgaagaagctcatcaactcgcagatcagcctcctc
atcggcaaaggcctccacgagtttgactccttgtgcgacccagaagtgaacgactttcgt
gccaagatgtgccagttctgcgaggaggcggccgcccgccggcagcagctgggctgggag
gcctggttgcagtacagcttccccctgcagctggagccctcggctcgaacctgggggcct
ggcaccctgcggctcccaaaccgggccctcctggtcaacgtcaagtttgagggcagcgag
gagagcttcaccttccaggtgtccaccaaggacgtgccgctggcgctgatggcctgtgcc
ctgcggaagaaggccacggtgttccggcagccgctggtggagcagccggaagactacacg
ctgcaggtgaacggcaggcatgagtacctgtacggcagctacccgctctgccagttccag
gtccagaaaccacgtgccaagccgcctcccattcctgcaaagaagcccttctctgtgtcc
ctgtggtccctggagcagccgttctgcatcgagctcatccagggcagcaaagtgaacgcc
gacgagcggatgaagctggtggtgcaggcagggcttttccacggcaacgagatgctgtgc
aagacggtgtccagctcggaggtgagcgtgtgctcggaacctgtgtggaagcagcggctg
gagttcgacatccacatctgcgacctgccccgcatggcccgtctctgctttgcactgtac
gccgtgatcgagaaagccaagaaggcccgctccaccaagaagaagtccaagaaggcggac
tgccccattgcctgggccaacctcatgctgtttgactacaaggaccagcttaagactggg
gaacgctgtctctacatgtggccctccgtcccagatgagaagggcgagctgctgaacccc
acaggcactgtgcgtagtaaccccaacacggatagcgccgccgccctgctcatctgcctg
cctgaggtggccccgcaccccgtgtactatcccgccctggagaagctgctgggagggatg
gtcttggcatctcgtgggtggaggccagagctactgtggatatgcctccatgcacgggac
agcgccccctcaaggatgatcggggtggcgaccccctgcctgggggtcctgcctgggctg
ttccaggccctgggggacgctgagtgcagctgtttgttgcagatcttggagctggggcgg
cacagtgagtgtgtacatgtcactgaggaggagcagctgcagctgcgggaaatcctggag
cggcgggggtctggggagctgtatgagcatgagaaggacctggtgtggaagctgcggcac
gaagtccaggagcacttcccggaggcgctagcccggctgctgctggtcaccaagtggaac
aagcacgaggatgtggcccagatgctctacctgctgtgctcctggccggagctgcctgtc
ctgagcgccctggagctgctggacttcagcttccctgattgccacgtaggctcctttgcc
atcaagtcgctgcggaaactgacggacgatgagctgttccagtacttgctgcagctggtg
caggtgctaaagtatgagtcctacctggactgcgagctgaccaaattcctgctggaccgg
gccctggccaaccgcaagatcggccacttccttttctggcacctccgctccgagatgcac
gtgccgtcggtggccctgcgcttcggcctcatcttggaggcctactgcaggggcagcacc
caccacatgaaggtgctgatgaagcagggggaagcactgagcaaactgaaggcactgaac
gacttcgtcaagctgagctctcagaagacccccaagccccagacgaaggagctgatgcac
ttgtgcatgcggcaggaggcctacctagaggccctctcccacctgcagtccccactcgac
cccagcaccctgctggctgaagtctgtgtggagcagtgcaccttcatggactccaagatg
aagcccctgtggatcatgtacagcaacgaggaggcaggcagcggcggcagcgtgggcatc
atctttaagaacggggatgacctccggcaggacatgctgaccctgcagatgatccagctc
atggacgtcctgtggaagcaggaggggctggacctgaggatgaccccctacggctgcctc
cccaccggggaccgcacaggcctcattgaggtggtactccgctcagacaccattgccaac
atccaactcaacaagagcaacatggcagccacagccgccttcaacaaggatgccctgctc
aactggctgaagtccaagaacccaggggaggccctggatcgagccattgaggagttcacc
ctctcctgtgctggctactgtgtggccacatatgtgctgggcatcggcgatcggcacagc
gacaacatcatgatccgagagagtgggcagctgttccacattgattttggccactttctg
gggaatttcaagaccaagtttggaatcaaccgtgagcgtgtcccattcatcctcacctat
gactttgtccatgtgattcagcaggggaagactaataacagtgagaaatttgaaaggttc
cggggctactgtgaaagggcctacaccatcctgcggcgccatgggcttctcttcctccac
ctctttgccctgatgcgggcggcaggcctgcctgagctcagctgctccaaagacatccag
tacctcaaggactccctggcactggggaaaacagaggaggaggcgctgaagcacttccga
gtgaagtttaatgaagccctccgtgagagctggaaaaccaaagtgaactggctggcccac
aacgtgtccaaggacaacaggcagtag

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