KEGG   Macaca fascicularis (crab-eating macaque): 102146644Help
Entry
102146644         CDS       T02918                                 

Gene name
PIK3CG
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:mcf00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102146644 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102146644 (PIK3CG)
   04015 Rap1 signaling pathway
    102146644 (PIK3CG)
   04012 ErbB signaling pathway
    102146644 (PIK3CG)
   04370 VEGF signaling pathway
    102146644 (PIK3CG)
   04630 Jak-STAT signaling pathway
    102146644 (PIK3CG)
   04668 TNF signaling pathway
    102146644 (PIK3CG)
   04066 HIF-1 signaling pathway
    102146644 (PIK3CG)
   04068 FoxO signaling pathway
    102146644 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    102146644 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    102146644 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    102146644 (PIK3CG)
   04152 AMPK signaling pathway
    102146644 (PIK3CG)
   04150 mTOR signaling pathway
    102146644 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102146644 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    102146644 (PIK3CG)
  Cell communication
   04510 Focal adhesion
    102146644 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102146644 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    102146644 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    102146644 (PIK3CG)
   04660 T cell receptor signaling pathway
    102146644 (PIK3CG)
   04662 B cell receptor signaling pathway
    102146644 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    102146644 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    102146644 (PIK3CG)
   04670 Leukocyte transendothelial migration
    102146644 (PIK3CG)
   04062 Chemokine signaling pathway
    102146644 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    102146644 (PIK3CG)
   04915 Estrogen signaling pathway
    102146644 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    102146644 (PIK3CG)
   04917 Prolactin signaling pathway
    102146644 (PIK3CG)
   04921 Oxytocin signaling pathway
    102146644 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    102146644 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102146644 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102146644 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102146644 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    102146644 (PIK3CG)
   04722 Neurotrophin signaling pathway
    102146644 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102146644 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    102146644 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102146644 (PIK3CG)
   05205 Proteoglycans in cancer
    102146644 (PIK3CG)
   05203 Viral carcinogenesis
    102146644 (PIK3CG)
   05210 Colorectal cancer
    102146644 (PIK3CG)
   05212 Pancreatic cancer
    102146644 (PIK3CG)
   05214 Glioma
    102146644 (PIK3CG)
   05221 Acute myeloid leukemia
    102146644 (PIK3CG)
   05220 Chronic myeloid leukemia
    102146644 (PIK3CG)
   05218 Melanoma
    102146644 (PIK3CG)
   05211 Renal cell carcinoma
    102146644 (PIK3CG)
   05215 Prostate cancer
    102146644 (PIK3CG)
   05213 Endometrial cancer
    102146644 (PIK3CG)
   05222 Small cell lung cancer
    102146644 (PIK3CG)
   05223 Non-small cell lung cancer
    102146644 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102146644 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102146644 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102146644 (PIK3CG)
   05166 HTLV-I infection
    102146644 (PIK3CG)
   05162 Measles
    102146644 (PIK3CG)
   05164 Influenza A
    102146644 (PIK3CG)
   05161 Hepatitis B
    102146644 (PIK3CG)
   05160 Hepatitis C
    102146644 (PIK3CG)
   05169 Epstein-Barr virus infection
    102146644 (PIK3CG)
   05146 Amoebiasis
    102146644 (PIK3CG)
   05145 Toxoplasmosis
    102146644 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    102146644 (PIK3CG)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102146644 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
3
AA seq 1102 aa AA seqDB search
MELENYEQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRKCKSPETALLH
VAGHGNVEQMKAQVWLRALETSMASDFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKATHRSPGQIHLVQRRPPSEESQAFQRQLTALIGYDVTDVSNVHDDELEFTRRGL
VTPRMAEVASRDPRLYAMHPWVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDT
PGTILQSFFTKMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPAVSSKASAESPSSESKGKVQLLYYVNLLLIDHRFLLRRGEY
VLHMWQISGKGEDQGSFSADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLHDFTQQVQVIEMLQKVTLDIKSLSAEKYDVSSQVISQLKQKLENLQNSQLP
KSFRVPYDPGLKAGALAIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDTCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
NT seq 3309 nt NT seq  +upstreamnt  +downstreamnt
atggagctggagaactatgaacagcccgtggtgctgagagaggacaactgccgcaggcgc
cggaggatgaagccgcgcagtgctgcggccagcctgtcctccatggagctcatccccatc
gagttcgtgctgcccaccagccagcgcaaatgcaagagccccgaaacggcgctgctgcac
gtggcgggccacggcaacgtggagcagatgaaggcccaggtgtggctgcgagcgctggag
accagcatggcgtcggacttctaccaccgactggggccggaccacttcctcctgctctac
cagaagaaggggcagtggtatgagatctacgacaagtaccaggtggtgcagactctggac
tgcctgcgctactggaaggccactcaccggagcccgggccagatccacctggtgcagcgg
cgcccgccctctgaggagtcgcaggccttccagcggcagctcaccgcgctgattggctat
gatgtcaccgacgtcagcaacgtgcacgacgacgagctggagttcacgcgccgcggcctg
gtgacgccgcgcatggcggaggtggccagtcgtgacccgaggctctacgccatgcacccc
tgggtgacgtccaagcccctcccggagtacctgtggaagaagattgccaacaactgcatc
ttcatcgtcattcaccgcagcaccaccagccagaccattaaggtctcacccgacgacacc
cctggaaccatcctgcagagcttcttcaccaagatggccaagaagaaatctctgatggat
attcctgaaagccaaagcgaacaggattttgtgctgcgcgtctgtggccgggatgagtac
ctggtgggcgaaacgcccatcaaaaacttccagtgggtgaggcactgcctcaagaacgga
gaagaaattcacctggtactggacacgcctccagacccggccctagacgaggtaaggaag
gaagagtggccactggtggatgactgcacaggagtcactggctaccatgagcagctgacc
atccacggcaaggaccacgagagtgtgttcaccgtgtccctgtgggactgcgaccgcaag
ttcagggtcaagatcagaggcattgatatccccgtcctgccccggaacaccgacctcaca
gtttttgtagaggcaaacatccagcatgggcagcaagtcctttgccaaaggagaaccagc
cccaaacccttcacagaggaggtgctctggaatgtgtggcttgagttcagtatcaaaatc
aaagacttgcccaaaggagctctactgaacctccagatctactgtggtaaagctccagca
gtgtccagcaaggcctctgcagagtcccccagttctgagtccaagggcaaagttcagctt
ctctattatgtgaacctgctgctgatagaccaccggttccttctgcgccgtggagaatac
gttctccacatgtggcagatatccgggaagggagaagaccaaggaagcttcagtgctgac
aaactcacgtctgcaactaacccagacaaggagaactcaatgtccatctccattcttctg
gacaattactgccacccgatagccctgcctaagcatcagcccacccctgacccggaaggg
gaccgggttcgagcagaaatgcccaaccagcttcgcaagcaattggaggcgatcatagct
actgatccacttaaccctctcacagcagaggacaaagaattgctctggcactttagatat
gaaagccttaagcacccaaaagcatatcctaagctatttagttcagtgaaatggggacag
caagaaattgtggccaaaacataccaattgttggccagaagggaagtctgggatcaaagt
gctttggatgttgggttaacaatgcagctcctggactgcaacttctcagatgaaaatgta
agagccattgcagttcagaaactggagagcttggaggacgatgatgttctgcattacctt
ctacagttggtacaggctgtgaaatttgaaccataccatgatagcgcccttgccagattt
ctgctgaagcgtggtttaagaaacaaaagaattggtcactttttgttttggttcttgaga
agtgagatagcccagtccagacactatcagcagaggttcgccgtgattctggaagcctat
ttgaggggctgtggcacagccatgctgcacgactttacccaacaagtccaagtaatcgag
atgttacaaaaagtcacccttgatattaaatcgctctctgctgaaaagtatgatgtcagt
tcccaagttatttcacaacttaaacaaaagcttgaaaacctgcagaattctcaactcccc
aaaagctttagagttccgtatgatcctggactgaaagcaggagcgctggcaattgaaaaa
tgtaaagtaatggcctccaagaaaaaaccactgtggcttgagtttaaatgtgccgatcct
acagccctatcaaatgaaacaattggaattatatttaaacatggtgatgatctgcgccaa
gacatgcttattttacagattctacgaatcatggagtccatttgggagactgaatctttg
gatctgtgcctcctgccatatggttgcatttcaactggtgacaaaataggaatgatcgag
attgtgaaagacgccacaacaattgccaaaattcagcaaagcaccgtgggcaacacggga
gcatttaaagatgaagtcctgaatcactggctcaaagaaaaatctcctactgaagaaaag
tttcaggcagccgtggagagatttgtttattcctgtgcaggctactgtgtggcaaccttt
gttcttggaataggcgacagacacaatgacaatattatgatcacagagacaggaaaccta
tttcatattgacttcgggcacattcttgggaattacaaaagtttcctgggcattaataaa
gagagagtgccatttgtgctaacccctgacttcctgttcgtcatgggaacttctggaaag
aagacaagcctacacttccagaaatttcaggacacctgtgttaaggcttatctagccctt
cgtcatcacacaaacctactgatcatcctgttctccatgatgctgatgaccggaatgccc
cagttaacaagcaaagaagacattgaatatatccgggatgccctcacagtggggaaaaat
gaggaggatgctaaaaagtattttcttgatcagatcgaagtgtgcagagacaaaggatgg
actgtgcagtttaattggtttctacatcttgttcttggcatcaaacaaggagaaaaacat
tcagcctaa

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