KEGG   Macaca fascicularis (crab-eating macaque): 7857746
Entry
7857746           CDS       T02918                                 
Symbol
ND4, KEG98_p04
Name
(RefSeq) NADH dehydrogenase subunit 4
  KO
K03881  NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf00190  Oxidative phosphorylation
mcf01100  Metabolic pathways
mcf04714  Thermogenesis
mcf04723  Retrograde endocannabinoid signaling
mcf05010  Alzheimer disease
mcf05012  Parkinson disease
mcf05014  Amyotrophic lateral sclerosis
mcf05016  Huntington disease
mcf05020  Prion disease
mcf05022  Pathways of neurodegeneration - multiple diseases
mcf05208  Chemical carcinogenesis - reactive oxygen species
mcf05415  Diabetic cardiomyopathy
Module
mcf_M00142  NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    7857746 (ND4)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    7857746 (ND4)
  09159 Environmental adaptation
   04714 Thermogenesis
    7857746 (ND4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    7857746 (ND4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    7857746 (ND4)
   05012 Parkinson disease
    7857746 (ND4)
   05014 Amyotrophic lateral sclerosis
    7857746 (ND4)
   05016 Huntington disease
    7857746 (ND4)
   05020 Prion disease
    7857746 (ND4)
   05022 Pathways of neurodegeneration - multiple diseases
    7857746 (ND4)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    7857746 (ND4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:mcf03029]
    7857746 (ND4)
Enzymes [BR:mcf01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     7857746 (ND4)
Mitochondrial biogenesis [BR:mcf03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    7857746 (ND4)
SSDB
Motif
Pfam: Proton_antipo_M Oxidored_q5_N
Other DBs
NCBI-GeneID: 7857746
NCBI-ProteinID: YP_002884235
UniProt: C3W4Z4
Position
MT:10759..12136
AA seq 459 aa
MLKMIIPTTMLLPMTWLSKNDTIWINLTMHSLAISLIPLLFLNQTNTNLLNHSTYLSSDP
LTTPLLMLTAWLLALMITASQYHLHNESPPRKKFYLSMMVFLQISLIFTFMATELIMFYI
LFETTLIPTLIIITRWGSQAERLNPGMYFLFYTLAGSVPLLIMLIYAYNNLGSLNITLLT
LVAQKLTTTWSHSLTWLTCMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLATVLLKLGG
YGMMWLTSILSLTTEYMTYPFLMLSLWGMIMTSSTCLRQTDLKSLIAYSSVSHMALVIVA
SLIQTPWSFSGATVLMIAHGLTSSMYFCLANSNYERTHSRTMLLSRGLQILLPLMAFWWL
AASLTNLALPPTINLLGELFVITTSFSWSHITIVLTGLNMLITALYSLHMFITMQRGTLT
HHMINMKPPFTRENMLMFMHLAPIILLSLNPNIILGFTS
NT seq 1378 nt   +upstreamnt  +downstreamnt
atgctaaagataatcatcccaacaaccatactactacctataacatggctttctaaaaac
gacacgatttgaatcaacttaactatacacagcttagctatcagcctcattcccttacta
ttcctcaaccaaaccaacactaacctcctcaatcactcaacctatctatcttctgaccca
ctaacaacacccctcctaatattaaccgcctgactcttagctcttataatcacagcaagc
caataccacttacacaatgaatcccctccacgaaaaaagttttacctctctataatggtc
ttcctacaaatctctttaattttcacatttatagctacagaactaatcatattttatatt
ctatttgagaccactctcattcctaccctaattatcatcacccgatgaggcagccaagca
gaacgccttaacccaggcatatacttcctcttctatacactagccggctctgtcccccta
cttattatgctaatctatgcttataataatttaggctctctaaatatcacattactaacg
cttgtagctcaaaaactaacaactacctgatcccatagtcttacctgactaacatgcata
atagccttcatagtaaaaatacccctatatggcttacacttatgacttcccaaagcccat
gttgaagctcccattgctgggtcaatagtcctcgccacagtactcctgaaactaggtggc
tatggcataatatgactcacctctatccttagtctcacaacagaatacataacctacccc
ttcctcatactatctttatgaggcataatcataacaagctcaacctgtcttcgacaaaca
gacctaaaatcacttatcgcatactcttctgtaagccacatagcccttgtaattgtagcc
tctctcatccaaaccccctgaagcttttccggcgcaaccgtccttataatcgcccacggg
ctcacctcttccatgtacttctgcctagccaattcaaactatgagcgcacccatagccgt
accatactactatcccgaggacttcaaattctacttccactaatagccttctgatggctc
gcagcaagccttactaaccttgccctacctcccactattaatctactaggcgaactcttt
gtaatcacaacctcattttcctgatcccatatcaccattgtattaacgggccttaacata
ctgatcacagccctctactctctccacatgttcattacaatacaacgaggaacactcaca
caccacataatcaatataaaaccccccttcacacgagaaaacatattaatattcatacac
ctcgctccaattatccttctatccctcaaccccaacatcatcctgggatttacttcct

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (32)   

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