KEGG   Momordica charantia (bitter melon): 111015400
Entry
111015400         CDS       T05045                                 
Name
(RefSeq) bifunctional dihydrofolate reductase-thymidylate synthase 1-like
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
mcha  Momordica charantia (bitter melon)
Pathway
mcha00240  Pyrimidine metabolism
mcha00670  One carbon pool by folate
mcha00790  Folate biosynthesis
mcha01100  Metabolic pathways
mcha01232  Nucleotide metabolism
mcha01240  Biosynthesis of cofactors
Module
mcha_M00126  Tetrahydrofolate biosynthesis, GTP => THF
mcha_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mcha00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    111015400
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    111015400
   00670 One carbon pool by folate
    111015400
Enzymes [BR:mcha01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     111015400
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     111015400
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-GeneID: 111015400
NCBI-ProteinID: XP_022146106
UniProt: A0A6J1CYC5
Position
Unknown
AA seq 537 aa
MFCRVITCNMAGDPLTSSNGNANVIAPPDPRRTFQVVVAATENMGIGKDGKLPWRLPSDL
KYFKNITTTTSDHGKRNAVLMGRKTWESIPAEHRPLPGRLNVVLTRSGSFDIATVENVII
CGSITSALELLAASPYCLSIEKVFIIGGGEILREALNAPECDAIHVTDIQTCVECDTFIP
AIDKSMFQPWYSSFPVVENNLRYSFTSYVRVRSSIEPPIDQNNGLVSYSRPDSSNFEAKK
FSFLPKEIFERHEEYLYLNLVKEIISDGTSKDDRTGTGTLSRFGVQMRYNLRKTFPLLTT
KKVFWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLSEREEGDLGPVYG
FQWRHFGARYTDMHADYTGQGFDQLLDVINKIKTNPNDRRIILSAWNPSDLKLMALPPCH
MFAQFYVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLAQGDFIHVIGDAH
VYHTHVRPLQEQLQKLPKPFPILKINPEKKDIDSFIAADFELTGYDPHEKIAMKMAV
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgttttgtcgagttattacttgtaatatggctggtgatcctttgacaagttctaatggc
aacgccaatgtcattgcaccacctgatccgcggaggactttccaagtcgtcgtggctgct
actgaaaatatgggtattggtaaggatgggaagctaccatggaggctgccttctgatctc
aaatattttaaaaacataaccacaacaacatcagatcatgggaaaaggaatgcagttcta
atgggtcgaaaaacatgggagagtattcctgctgagcatcgaccactacctggtcgtctc
aatgttgttctaactcgttcggggagttttgacattgcaactgttgaaaatgttataata
tgtggtagtataacgtctgctttggaattattagcagcttctccttactgtttgtcaata
gagaaagtttttatcataggcggtggtgagatattaagggaagctctgaatgcccctgaa
tgtgatgctatccatgtcacagacattcagacatgtgtcgaatgtgataccttcatacca
gctattgataagtctatgtttcagccatggtactcatcctttcctgtggtggaaaataac
cttcgatattctttcactagttatgttcgtgtgaggagctcaattgaaccacccattgat
cagaacaatggtctggtctcttatagtaggcccgattcttctaattttgaggctaagaag
ttctctttcctgcctaaggagatttttgaaaggcacgaggagtacttgtatctaaatctt
gttaaggaaatcatctcagatggtacttctaaggatgatagaacaggaactggtactttg
tcaagattcggcgtccagatgcgatacaacttgcgcaaaacttttccactgcttactact
aagaaagtgttttggcgaggggttgttgaagaacttctttggttcatcagtgggtcaacc
aatgcaaaggttcttcaggagaaaggcattcatatatgggatggcaatgcatccagagat
tacctcgatagtattggtttgagcgaaagggaggagggtgacctgggacctgtatatggg
ttccagtggcgacactttggtgctaggtatactgacatgcatgctgactacactggtcaa
ggattcgatcagttgctagatgttattaacaagataaaaactaatcccaatgaccggagg
ataattctttccgcatggaatccatctgatctcaaactgatggcccttccgccttgccac
atgttcgctcagttttatgtagcgaatggggagttgtcgtgtcaaatgtatcagcgctct
gctgacatgggccttggcgttccatttaatattgcatcatatgctcttctgacatgcatg
attgctcatgtttgtgatctcgctcaaggcgacttcatacatgtgattggggacgctcat
gtttaccatactcatgtgaggccattgcaggagcagctccagaaactccccaaacctttc
cctattttgaagattaatcctgagaagaaggatatcgattctttcatagcagctgatttc
gaactaaccggttacgaccctcatgaaaagatagcaatgaaaatggcagtatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (6)   
   KEGG MODULE (3)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (2)   
   Pfam (2)   
All databases (43)   

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