KEGG   MODULE: M00309Help
Entry
M00309            Pathway   Module                                 

Name
Non-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate
Definition
K05308 (K11395,K18127) (K18020+K18021+K18022,K18128,K03738)
Module map
M00309

Orthology
K05308  
gluconate/galactonate dehydratase [EC:4.2.1.140] [RN:R01538 R03033]
K11395  
2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase [EC:4.1.2.55] [RN:R08570 R10616]
K18127  
2-dehydro-3-deoxy-D-gluconate aldolase [EC:4.1.2.51] [RN:R08570 R10616]
glyceraldehyde dehydrogenase large subunit [EC:1.2.99.8] [RN:R10324]
K18128  
glyceraldehyde dehydrogenase [EC:1.2.1.89] [RN:R10615]
K03738  
aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5] [RN:R08571]
Ortholog tableTaxonomy
Class
Pathway module; Carbohydrate and lipid metabolism; Central carbohydrate metabolism
BRITE hierarchy
Pathway
Carbon metabolism
Pentose phosphate pathway
Galactose metabolism
Reaction
Compound
C00257  
D-Gluconic acid
C00204  
2-Dehydro-3-deoxy-D-gluconate
C00577  
D-Glyceraldehyde
C00022  
Pyruvate
C00880  
D-Galactonate
C01216  
2-Dehydro-3-deoxy-D-galactonate
C00258  
D-Glycerate
Comment
Organism group: archaea
Other DBs
BSID: 
Reference
  Authors
Ahmed H, Ettema TJ, Tjaden B, Geerling AC, van der Oost J, Siebers B
  Title
The semi-phosphorylative Entner-Doudoroff pathway in hyperthermophilic archaea: a re-evaluation.
  Journal
Biochem J 390:529-40 (2005)
DOI:10.1042/BJ20041711
Reference
  Authors
Reher M, Fuhrer T, Bott M, Schonheit P
  Title
The nonphosphorylative Entner-Doudoroff pathway in the thermoacidophilic euryarchaeon Picrophilus torridus involves a novel 2-keto-3-deoxygluconate- specific aldolase.
  Journal
J Bacteriol 192:964-74 (2010)
DOI:10.1128/JB.01281-09

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