KEGG   MODULE: M00347Help
Entry
M00347            Pathway   Module                                 
Name
Methanogenesis, formate => methane
Definition
((K00123+K00125)-K00124-K00126-K00127) (K00200+K00201+K00202+K00203-K00204-K00205-K11261+K11260) K00672 K01499 (K00319,K13942) K00320 (K00440+K00441+K00442+K00443) (K00577+K00578+K00579+K00580+K00581-K00582-K00583+K00584) (K00399+K00401+K00402) (K03388+K03389+K03390)
Module map
M00347

Orthology
formate dehydrogenase [EC:1.2.1.2] [RN:R00519]
formylmethanofuran dehydrogenase [EC:1.2.99.5] [RN:R03015]
K00672  
formylmethanofuran--tetrahydromethanopterin N-formyltransferase [EC:2.3.1.101] [RN:R03390]
K01499  
methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27] [RN:R03464]
K00319  
methylenetetrahydromethanopterin dehydrogenase [EC:1.5.99.9] [RN:R04456]
K13942  
5,10-methenyltetrahydromethanopterin hydrogenase [EC:1.12.98.2] [RN:R04456]
coenzyme F420 hydrogenase [EC:1.12.98.1] [RN:R03025]
K00320  
coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase [EC:1.5.99.11] [RN:R04464]
tetrahydromethanopterin S-methyltransferase [EC:2.1.1.86] [RN:R04347]
methyl-coenzyme M reductase [EC:2.8.4.1] [RN:R04541]
heterodisulfide reductase [EC:1.8.98.1] [RN:R04540]
Ortholog tableTaxonomy
Class
Pathway module; Energy metabolism; Methane metabolism
BRITE hierarchy
Pathway
Methane metabolism
Reaction
Compound
C00058  
Formate
C00011  
CO2
C01001  
Formylmethanofuran
C01274  
5-Formyl-5,6,7,8-tetrahydromethanopterin
C04330  
5,10-Methenyltetrahydromethanopterin
C04377  
5,10-Methylenetetrahydromethanopterin
C01080  
Reduced coenzyme F420
C04488  
5-Methyl-5,6,7,8-tetrahydromethanopterin
C00876  
Coenzyme F420
C03920  
2-(Methylthio)ethanesulfonate
C04628  
N-(7-Mercaptoheptanoyl)threonine 3-O-phosphate
C01438  
Methane
C04832  
Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide
Comment
There is not mja:MJ_1190 in Refseq. (August 10, 2012)
HdrA (K03388) might be pseudogene in the M. jannaschii genome.
Other DBs
BSID: 
Reference
  Authors
Liu Y, Whitman WB
  Title
Metabolic, phylogenetic, and ecological diversity of the methanogenic archaea.
  Journal
Ann N Y Acad Sci 1125:171-89 (2008)
Reference
  Authors
Thauer RK, Kaster AK, Seedorf H, Buckel W, Hedderich R
  Title
Methanogenic archaea: ecologically relevant differences in energy conservation.
  Journal
Nat Rev Microbiol 6:579-91 (2008)
Reference
PMID:9102456
  Authors
Wilting R, Schorling S, Persson BC, Bock A
  Title
Selenoprotein synthesis in archaea: identification of an mRNA element of Methanococcus jannaschii probably directing selenocysteine insertion.
  Journal
J Mol Biol 266:637-41 (1997)
Reference
  Authors
Rother M, Krzycki JA
  Title
Selenocysteine, pyrrolysine, and the unique energy metabolism of methanogenic archaea.
  Journal
Archaea 2010 (2010)
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