KEGG   MODULE: zma_M00386Help
Entry
zma_M00386        Complex   Module                                 

Name
Cul4-DDB1-CSA complex
Definition
K03868+K10609+K10610+K10570
Module map
zma_M00386

Orthology
K03868  
RBX1; RING-box protein 1
K10609  
CUL4; cullin 4
K10610  
DDB1; DNA damage-binding protein 1
K10570  
ERCC8; DNA excision repair protein ERCC-8
Ortholog tableTaxonomy
Class
Structural complex; Genetic information processing; Ubiquitin system
BRITE hierarchy
Pathway
Ubiquitin mediated proteolysis
Nucleotide excision repair
Brite
Ubiquitin system
DNA repair and recombination proteins
Organism
Zea mays (maize) [GN:zma]
Gene
Rbx1; ring-box protein 1 [KO:K03868]
uncharacterized protein LOC100275606 [KO:K10570]
uncharacterized protein LOC100279448 [KO:K10610]
uncharacterized LOC100501431 [KO:K10609]
cullin-4 [KO:K10609]
RING-box protein 1-like [KO:K03868]
DNA damage-binding protein 1 [KO:K10610]
RING-box protein 1a [KO:K03868]
Comment
Substrate: CSB
Other DBs
BSID: 
Reference
  Authors
Groisman R, Polanowska J, Kuraoka I, Sawada J, Saijo M, Drapkin R, Kisselev AF, Tanaka K, Nakatani Y
  Title
The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.
  Journal
Cell 113:357-67 (2003)
DOI:10.1016/S0092-8674(03)00316-7
Reference
  Authors
Higa LA, Wu M, Ye T, Kobayashi R, Sun H, Zhang H
  Title
CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.
  Journal
Nat Cell Biol 8:1277-83 (2006)
DOI:10.1038/ncb1490
KO module

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