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Entry
zma_M00430        Complex   Module                                 

Name
Exon junction complex (EJC)
Definition
K12876+K12877+K14323+K13025+K14324+K13114+K12875+K14325+K12881+K12812+K13171+K14285+K14326+K14327+K14328
Module map
zma_M00430

Orthology
K12876  
RBM8A; RNA-binding protein 8A
K12877  
MAGOH; protein mago nashi
K14323  
CASC3; protein CASC3
K13025  
EIF4A3; ATP-dependent RNA helicase [EC:3.6.4.13]
K14324  
SAP18; histone deacetylase complex subunit SAP18
K13114  
PNN; pinin
K12875  
ACIN1; apoptotic chromatin condensation inducer in the nucleus
K14325  
RNPS1; RNA-binding protein with serine-rich domain 1
K12881  
THOC4; THO complex subunit 4
K12812  
UAP56; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]
K13171  
SRRM1; serine/arginine repetitive matrix protein 1
K14285  
NXT1_2; NTF2-related export protein 1/2
K14326  
UPF1; regulator of nonsense transcripts 1 [EC:3.6.4.-]
K14327  
UPF2; regulator of nonsense transcripts 2
K14328  
UPF3; regulator of nonsense transcripts 3
Ortholog tableTaxonomy
Class
Structural complex; Genetic information processing; RNA processing
BRITE hierarchy
Pathway
RNA transport
mRNA surveillance pathway
Spliceosome
Brite
zma03041 Spliceosome  
 
Organism
Zea mays (maize) [GN:zma]
Gene
putative pinin_SDK_memA domain family protein [KO:K13114]
cl8663_2a; THO complex subunit 4B [KO:K12881]
histone deacetylase complex subunit SAP18 [KO:K14324]
si946052g10b; uncharacterized protein LOC100272743 [KO:K12881]
gpm624; uncharacterized LOC100273717 [KO:K12812]
pco131625; uncharacterized LOC100278324 [KO:K12881]
protein mago nashi [KO:K12877]
THO complex subunit 4 [KO:K12881]
THO complex subunit 4C [KO:K12881]
THO complex subunit 4 [KO:K12881]
pco111548; uncharacterized protein LOC100280575 [KO:K12877]
RNA-binding protein 8A [KO:K12876]
pinin/SDK/memA/ protein conserved region containing protein [KO:K13114]
RNA-binding protein 8A [KO:K12876]
pco106378a; uncharacterized protein LOC100283928 [KO:K12876]
splicing factor PWI domain-containing protein isoform X1 [KO:K13171]
histone deacetylase complex subunit SAP18 [KO:K14324]
uncharacterized protein LOC100381870 [KO:K12875]
pco088497(644); uncharacterized protein LOC100384654 [KO:K12812]
uncharacterized protein LOC100502129 isoform X1 [KO:K12875]
regulator of nonsense transcripts 1 homolog [KO:K14326]
regulator of nonsense transcripts UPF2-like [KO:K14327]
DEAD-box ATP-dependent RNA helicase 2 [KO:K13025]
formin-like protein 5 isoform X2 [KO:K12875]
SR45_2; serine/arginine-rich splicing factor SR45-like [KO:K14325]
regulator of nonsense transcripts 1 homolog [KO:K14326]
regulator of nonsense transcripts UPF3-like [KO:K14328]
regulator of nonsense transcripts UPF3 [KO:K14328]
SR45_1; serine/arginine-rich splicing factor SR45-like [KO:K14325]
732749  
RH2; putative RH2 protein [KO:K13025]
Reference
  Authors
Tange TO, Shibuya T, Jurica MS, Moore MJ
  Title
Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.
  Journal
RNA 11:1869-83 (2005)
DOI:10.1261/rna.2155905
Reference
  Authors
Ballut L, Marchadier B, Baguet A, Tomasetto C, Seraphin B, Le Hir H
  Title
The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity.
  Journal
Nat Struct Mol Biol 12:861-9 (2005)
DOI:10.1038/nsmb990
Reference
  Authors
Tange TO, Nott A, Moore MJ
  Title
The ever-increasing complexities of the exon junction complex.
  Journal
Curr Opin Cell Biol 16:279-84 (2004)
DOI:10.1016/j.ceb.2004.03.012
KO module

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