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Entry
mdi_M00223        Complex   Module                                 

Name
Phosphonate transport system
Definition
K02044+K02042+K02041
Module map
mdi_M00223

Orthology
K02044  
phnD; phosphonate transport system substrate-binding protein
K02042  
phnE; phosphonate transport system permease protein
K02041  
phnC; phosphonate transport system ATP-binding protein
Ortholog tableTaxonomy
Class
Structural complex; Environmental information processing; Phosphate and amino acid transport system
BRITE hierarchy
Pathway
ABC transporters
Brite
Transporters
Organism
Methylobacterium extorquens DM4 [GN:mdi]
Gene
phnC; phosphonate ABC transporter ATP-binding protein [KO:K02041]
ptxB; phosphonate transport system substrate-binding protein [KO:K02044]
ptxC; phosphate permease component of ATP-dependent phosphate uptake system [KO:K02042]
Comment
Stoichiometry: 1:2:2
Substrate: Alkylphosphonate [CPD:C06235], Phosphate [CPD:C00009]
Other DBs
BSID: 
Reference
PMID:8388873 (phosphonate degradation)
  Authors
Metcalf WW, Wanner BL.
  Title
Mutational analysis of an Escherichia coli fourteen-gene operon for phosphonate degradation, using TnphoA' elements.
  Journal
J Bacteriol 175:3430-42 (1993)
Reference
PMID:1840580 (alkylphosphonate)
  Authors
Makino K, Kim SK, Shinagawa H, Amemura M, Nakata A.
  Title
Molecular analysis of the cryptic and functional phn operons for phosphonate use in Escherichia coli K-12.
  Journal
J Bacteriol 173:2665-72 (1991)
Reference
PMID:17074913 (phosphate)
  Authors
Gebhard S, Tran SL, Cook GM
  Title
The Phn system of Mycobacterium smegmatis: a second high-affinity ABC-transporter for phosphate.
  Journal
Microbiology 152:3453-65 (2006)
KO module

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