KEGG   Monodelphis domestica (opossum): 100009879Help
Entry
100009879         CDS       T01031                                 

Gene name
PIK3CG
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:mdo00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100009879 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100009879 (PIK3CG)
   04015 Rap1 signaling pathway
    100009879 (PIK3CG)
   04012 ErbB signaling pathway
    100009879 (PIK3CG)
   04370 VEGF signaling pathway
    100009879 (PIK3CG)
   04630 Jak-STAT signaling pathway
    100009879 (PIK3CG)
   04668 TNF signaling pathway
    100009879 (PIK3CG)
   04066 HIF-1 signaling pathway
    100009879 (PIK3CG)
   04068 FoxO signaling pathway
    100009879 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    100009879 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    100009879 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    100009879 (PIK3CG)
   04152 AMPK signaling pathway
    100009879 (PIK3CG)
   04150 mTOR signaling pathway
    100009879 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100009879 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    100009879 (PIK3CG)
  Cell communication
   04510 Focal adhesion
    100009879 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100009879 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    100009879 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    100009879 (PIK3CG)
   04660 T cell receptor signaling pathway
    100009879 (PIK3CG)
   04662 B cell receptor signaling pathway
    100009879 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    100009879 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    100009879 (PIK3CG)
   04670 Leukocyte transendothelial migration
    100009879 (PIK3CG)
   04062 Chemokine signaling pathway
    100009879 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    100009879 (PIK3CG)
   04915 Estrogen signaling pathway
    100009879 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    100009879 (PIK3CG)
   04917 Prolactin signaling pathway
    100009879 (PIK3CG)
   04921 Oxytocin signaling pathway
    100009879 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    100009879 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100009879 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100009879 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100009879 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    100009879 (PIK3CG)
   04722 Neurotrophin signaling pathway
    100009879 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100009879 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    100009879 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100009879 (PIK3CG)
   05205 Proteoglycans in cancer
    100009879 (PIK3CG)
   05203 Viral carcinogenesis
    100009879 (PIK3CG)
   05210 Colorectal cancer
    100009879 (PIK3CG)
   05212 Pancreatic cancer
    100009879 (PIK3CG)
   05214 Glioma
    100009879 (PIK3CG)
   05221 Acute myeloid leukemia
    100009879 (PIK3CG)
   05220 Chronic myeloid leukemia
    100009879 (PIK3CG)
   05218 Melanoma
    100009879 (PIK3CG)
   05211 Renal cell carcinoma
    100009879 (PIK3CG)
   05215 Prostate cancer
    100009879 (PIK3CG)
   05213 Endometrial cancer
    100009879 (PIK3CG)
   05222 Small cell lung cancer
    100009879 (PIK3CG)
   05223 Non-small cell lung cancer
    100009879 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100009879 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100009879 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100009879 (PIK3CG)
   05166 HTLV-I infection
    100009879 (PIK3CG)
   05162 Measles
    100009879 (PIK3CG)
   05164 Influenza A
    100009879 (PIK3CG)
   05161 Hepatitis B
    100009879 (PIK3CG)
   05160 Hepatitis C
    100009879 (PIK3CG)
   05169 Epstein-Barr virus infection
    100009879 (PIK3CG)
   05146 Amoebiasis
    100009879 (PIK3CG)
   05145 Toxoplasmosis
    100009879 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    100009879 (PIK3CG)
Enzymes [BR:mdo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100009879 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
8
AA seq 1099 aa AA seqDB search
MDLEDHEPVVLREDHRGRRRRMKPQSAGISSSSMERIPIEFILPTSHQNTKATETVILEA
AGNCNVEQVKAQVWMQAMETSTTMQFYHQSSPEQFLLLYQKKGQWYEIYDKYQLIQTLDC
VKYWKALQKNMGQIHVVQRQPPTEETREFQQQLNDLIGYDVTNMSNVHDDELEFTRRRLV
TPRMMEVARRDPKLYAMHPWVTSKPLPTYLLKKIVNNCIFIVIHRSTTSQTIKVSADDTP
GTILQSFFTKMAKKKSLMDIPESQSELDFVLRVCGRDEYIVGETPIKNFQWIRHCLKNGE
EIHLVLDAPPDPGQDEVRKEEWPLVDDCTGVTGYHEQLTINGKNHERVFTLSLWDCDQRF
RVKIRGIDIPVLPRNTELTVFVEANIQHGQQVLCQRRTTSKPFTEEVLWNVWLEFGIKIK
DLPKGAILNLQIYCGKATAQSSKAEISSFETKGKTQLLYYVNLLLIDHRFLLRHGEYVLH
MWKISGKGEDQGSINADKLTSATNPDTENSMSISILLDNYCHPIALPKHRPTPDPEGDRV
RGEMPNQLRKQLEEIIATDPLNPLTAKDKELLWHFRYESLKHPKAYPKLFSSVKWGQQEI
VAKTYQLLARREAWDQSDLDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYLLQL
VQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAYLRG
CGMAMLEDFTKQVQVIRMLQKVTIDIKSLSAEKYDVTSQVIAQLKQKLENLQNSNLPKNF
RVPYDPGLRAGTLVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDML
ILQILRIMGSIWEAESLDLCLQPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTGAFK
DEVLNHWLKEKCPIEEKFQAAVEKFVYSCAGYCVATFVLGIGDRHNDNIMITETGNLFHI
DFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKSSLHFQKFQDICVKAYLALRQH
TNLLIILFSMMLMTGMPQLTSKEDIEYIRDTLTVGKNEEDAKKYFLDQIEVCRDKGWTVQ
FNWFLHLVLGIKQGEKHSA
NT seq 3300 nt NT seq  +upstreamnt  +downstreamnt
atggatttggaggaccatgagcccgtggttctgagagaagaccacaggggaaggaggcgg
agaatgaagccacaaagtgctggcatcagctcatcttcaatggagcgcattcccatagaa
tttatcctgcccaccagccaccagaacaccaaagccaccgaaacagtgatcctagaagca
gctggaaattgtaatgtggaacaggtgaaagcacaggtgtggatgcaggccatggagact
agcacaaccatgcagttctatcaccagtcctccccagagcaatttctcctgctgtaccag
aaaaagggacagtggtatgagatctatgacaagtaccaattgatacagacattggactgt
gtgaagtactggaaagctctccagaagaacatgggccagatccatgtagtccagaggcag
ccacccacagaggaaactcgggagttccaacagcagctaaatgacctgattggctatgac
gttactaacatgagcaacgtccatgacgatgagctagaattcacccggcgccggcttgtc
actccacggatgatggaggtcgcaagacgagaccccaaactctatgccatgcatccttgg
gtgacttccaaaccactccccacatacctactgaaaaagattgtcaacaattgcattttc
atcgtcatccaccgaagtaccacaagccagaccatcaaggtctctgcagatgatacccca
ggcacgatcttacagagcttcttcaccaagatggctaagaagaagtcactaatggacatc
cctgagagtcagagtgagctggactttgtgcttcgggtctgtggccgggatgagtatatc
gtgggtgagacaccgatcaagaatttccagtggattaggcactgtctcaagaatggcgaa
gagattcaccttgtgctagatgctcctcctgacccaggacaggatgaggtgaggaaggag
gagtggccactcgtagatgactgcacaggagtcacaggctaccatgagcagctgacaata
aatgggaagaatcatgagagagtgttcactctttccctgtgggactgtgaccaaaggttc
agggtgaagatcaggggcattgacatccctgtgctcccacggaacactgagctcacagtc
tttgtggaagcaaacatccagcatggacagcaggtcctttgtcaaagacgaaccacctct
aaacctttcacagaggaggtgctctggaatgtgtggcttgagtttggtatcaaaatcaag
gacttgcccaaaggggctatactgaaccttcagatttactgtgggaaagcaacagctcag
tcttccaaagctgagatttctagcttcgagaccaaaggcaaaactcagctcctctattat
gtgaacctactgctgattgaccaccgatttctcctgaggcacggagaatatgtcctgcac
atgtggaagatatcagggaaaggagaggaccaagggagcatcaatgcagacaagcttaca
tcagcaaccaacccagatacggagaattccatgtcaatctccatccttctggacaattat
tgtcacccaatagccttgcccaagcacaggcccacgcctgaccctgaaggggacagggtt
aggggagaaatgcccaatcagctacgtaaacagctggaagagatcatagccactgaccca
cttaacccactcacagcaaaggacaaggaattactatggcattttaggtatgaaagcctg
aagcaccccaaagcatatcctaaactgtttagctcagtgaaatggggacagcaagaaatt
gtggccaaaacataccagttgttagccagaagagaagcttgggaccaaagcgatttggat
gttgggttaacaatgcaactcttagactgcaacttttcagatgaaaatgtaagagctatt
gcagtgcaaaagctagaaagcttggaggatgatgatgtcttgcattacctgctgcaacta
gttcaggctgtgaaatttgaaccttaccatgacagtgctcttgccagatttctgctgaaa
cgtggtttgagaaacaagagaattggtcacttcttgttctggtttctgagaagtgagatt
gctcagtccagacactaccaacaacggtttgcagtgatccttgaagcctatctgaggggc
tgtggcatggctatgttagaggatttcacaaaacaggttcaagtcatcaggatgctacaa
aaagtcactattgatattaagtcactttctgcagaaaagtatgatgtcacctcccaagtt
atcgcacaacttaagcaaaagcttgaaaaccttcagaattctaatcttccaaaaaatttt
agagttccctatgatcccggcctgagagcaggaacactcgtgattgaaaaatgtaaagta
atggcatccaaaaagaagcccttatggcttgaatttaaatgtgctgatcccacagccctg
tccaatgaaaccataggaattatcttcaaacacggggatgatttgcgtcaagacatgctc
attttgcaaattcttcgaattatgggatctatttgggaagcagagtcattggacttgtgc
ctgcagccatatggttgcatttcaactggagacaaaataggaatgattgaaattgtgaag
gatgctacaacgattgccaaaattcagcagagcacagtgggtaatactggagcatttaag
gatgaagtgctaaatcattggctcaaagaaaaatgcccaattgaagaaaagttccaggca
gcagtggagaaatttgtatattcatgtgctggctactgtgtggcaacctttgttcttggt
attggagacagacacaatgacaacattatgatcacagaaacaggaaatctgtttcatatt
gactttggccacattcttgggaattataaaagtttcctgggcatcaacaaagagagagtt
ccatttgtgctaactcctgacttcctcttcgtgatgggaacttctggaaagaaaagcagc
ctacacttccagaaatttcaggacatttgtgtcaaggcttacttagctcttcggcaacac
actaacctgctgattatcctgttttccatgatgctgatgactggaatgccccagttaact
agcaaggaagatattgaatatatccgggataccctgacagtggggaaaaatgaagaggac
gccaaaaagtatttccttgatcagatagaagtttgtagagacaaaggctggactgtgcag
tttaattggttcttacatcttgttcttggaatcaaacaaggagaaaaacattctgcctaa

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