KEGG   Monodelphis domestica (opossum): 100010412Help
Entry
100010412         CDS       T01031                                 

Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:mdo00562]
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:mdo04014]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:mdo04015]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:mdo04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:mdo04370]
Environmental Information Processing; Signal transduction; Jak-STAT signaling pathway [PATH:mdo04630]
Environmental Information Processing; Signal transduction; TNF signaling pathway [PATH:mdo04668]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:mdo04066]
Environmental Information Processing; Signal transduction; FoxO signaling pathway [PATH:mdo04068]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:mdo04070]
Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:mdo04151]
Environmental Information Processing; Signal transduction; mTOR signaling pathway [PATH:mdo04150]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:mdo04810]
Cellular Processes; Cell growth and death; Apoptosis [PATH:mdo04210]
Cellular Processes; Cell communication; Focal adhesion [PATH:mdo04510]
Organismal Systems; Immune system; Toll-like receptor signaling pathway [PATH:mdo04620]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:mdo04650]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:mdo04660]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:mdo04662]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:mdo04664]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:mdo04666]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:mdo04670]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:mdo04062]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:mdo04910]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:mdo04915]
Organismal Systems; Endocrine system; Progesterone-mediated oocyte maturation [PATH:mdo04914]
Organismal Systems; Endocrine system; Prolactin signaling pathway [PATH:mdo04917]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:mdo04921]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:mdo04919]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:mdo04261]
Organismal Systems; Digestive system; Carbohydrate digestion and absorption [PATH:mdo04973]
Organismal Systems; Excretory system; Aldosterone-regulated sodium reabsorption [PATH:mdo04960]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:mdo04725]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:mdo04722]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:mdo04750]
Organismal Systems; Development; Osteoclast differentiation [PATH:mdo04380]
Human Diseases; Cancers; Pathways in cancer [PATH:mdo05200]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:mdo05205]
Human Diseases; Cancers; Viral carcinogenesis [PATH:mdo05203]
Human Diseases; Cancers; Colorectal cancer [PATH:mdo05210]
Human Diseases; Cancers; Pancreatic cancer [PATH:mdo05212]
Human Diseases; Cancers; Glioma [PATH:mdo05214]
Human Diseases; Cancers; Acute myeloid leukemia [PATH:mdo05221]
Human Diseases; Cancers; Chronic myeloid leukemia [PATH:mdo05220]
Human Diseases; Cancers; Melanoma [PATH:mdo05218]
Human Diseases; Cancers; Renal cell carcinoma [PATH:mdo05211]
Human Diseases; Cancers; Prostate cancer [PATH:mdo05215]
Human Diseases; Cancers; Endometrial cancer [PATH:mdo05213]
Human Diseases; Cancers; Small cell lung cancer [PATH:mdo05222]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:mdo05223]
Human Diseases; Endocrine and metabolic diseases; Type II diabetes mellitus [PATH:mdo04930]
Human Diseases; Endocrine and metabolic diseases; Non-alcoholic fatty liver disease (NAFLD) [PATH:mdo04932]
Human Diseases; Infectious diseases; Bacterial invasion of epithelial cells [PATH:mdo05100]
Human Diseases; Infectious diseases; HTLV-I infection [PATH:mdo05166]
Human Diseases; Infectious diseases; Measles [PATH:mdo05162]
Human Diseases; Infectious diseases; Influenza A [PATH:mdo05164]
Human Diseases; Infectious diseases; Hepatitis B [PATH:mdo05161]
Human Diseases; Infectious diseases; Hepatitis C [PATH:mdo05160]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:mdo05169]
Human Diseases; Infectious diseases; Amoebiasis [PATH:mdo05146]
Human Diseases; Infectious diseases; Toxoplasmosis [PATH:mdo05145]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:mdo05142]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
7
AA seq 1068 aa AA seqDB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ
LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDVHAPHSRALYVYPPNVESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEHVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEASTKSLWVVNSALRIRILCATYVNVNIRDIDKIYVRTGI
CHGGEPLCDNVNTQRVPCSNPRWNEWLMYDIYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMAVIEEHANWTVSRELGFNYSHAGLSNRIARDNELRENDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVSIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt NT seq  +upstreamnt  +downstreamnt
atgcctccaagaccatcatccggtgaactgtggggcatccatttgatgcccccaagaatc
ttagtagaatgtctactacctaatggaatgatagtgactttagaatgcctccgtgaggct
acattagtaactattaaacacgagctatttaaagaagcaaggaaataccctcttcaccag
ctccttcaggatgaaacttcttacattttcgtaagcgttactcaagaagcagaaagggaa
gaattttttgatgaaactcgacgactttgtgacctacggctttttcagccttttctaaaa
gtcatcgaaccagtaggcaaccgagaagaaaagattctcaatcgagaaattggttttgct
attggtatgcctgtttgtgaatttgatatggttaaagatccagaagtacaagatttccga
agaaatattcttaatgtttgtaaagaggctgtggacctgagggatgtccatgcaccccat
agtagagcattatatgtctatcctccaaatgtagaatcttcaccagaattgccaaagcat
atatacaataaattagataaagggcaaataatagtggtgatttgggtgatagtttcccca
aacaatgacaagcagaagtacactttaaaaatcaatcatgactgtgtaccagaacatgtg
atcgctgaagcaatccggaaaaaaacgcggagtatgttgctgtcatcggagcagctgaag
ctctgcgttttagagtatcagggcaaatacattttaaaagtgtgtggatgtgatgagtat
ctgctagaaaaatatcctcttagccaatataagtacataagaagctgtataatgcttggt
cggatgcccaatctgatgctgatggctaaagaaagtctttacacccagctaccactggat
acttttacaatgccatcttattccagacgaatctccacagccacaccatacatgaatgga
gaagcttcaaccaaatccctttgggtcgtaaatagtgcactccggataagaattctttgt
gcaacttatgtaaatgtaaatattcgagacattgacaagatctatgttcgaacaggtatc
tgccatgggggagagccattatgtgacaatgtgaatactcaaagagtaccttgttccaat
cccaggtggaatgaatggctgatgtatgatatatacattcctgatcttccacgagctgct
cgactttgcctttccatttgttctgttaaaggcaggaaaggtgcaaaagaggaacactgt
ccattggcttggggaaatataaacctctttgattatacggacactctggtatcggggaaa
atggctttgaatctgtggccagtacctcatggattagaagatttgctcaatcctattgga
gttactgggtcaaatcccaataaggaaactccatgtttagagctggaatttgactggttt
agcaatcctgtaaagttcccagatatggcagtgattgaagaacatgcgaattggactgta
tctcgagaactaggatttaactattcccatgctgggctgagtaataggatagctcgagat
aatgaattaagagaaaacgacaaagaacaacttcgagcaatttgtactcgagaccctctg
tctgagatcactgagcaagaaaaggactttctttggagtcacaggcattattgtgtcagt
atcccagaaattctacctaaacttcttttatccgttaaatggaattctagagatgaagta
gcccagatgtattgcttagtaaaagattggcccccaatcaaaccagaacaggccatggaa
cttttggactgtaattatccagaccctatggttcgagcttttgctgttcgctgcctggaa
aaatatttaactgatgacaaactttctcagtacttaattcaactagttcaggttctgaag
tatgaacagtatttggataacctgcttgtgagatttttactcaagaaagcactaacaaat
caaaggataggacactttttcttttggcatttaaagtctgagatgcataataaaactgtc
agtcaaagatttggcttacttttggagtcctattgccgagcgtgtgggatgtatctaaag
catttgaatcggcaggtggaggccatggagaaactgattaacctcactgacattctcaaa
caggagaagaaggatgagactcaaaaggtacaaatgaagttcttggttgaacaaatgagg
cggcctgattacatggatgctttacaaggctttatctctccccttaatcctgctcatcaa
ctaggaaatctcaggcttgaggagtgtcggattatgtcttctgcaaaaagaccactctgg
ttgaattgggagaacccagacatcatgtcagagttactatttcagaacaatgagatcatc
tttaaaaatggggatgacttacgacaagatatgctaactcttcagatcattcgaattatg
gaaaatatctggcaaaatcagggtcttgatcttcggatgctgccttatggttgcctatca
attggggactgtgttggcctcattgaggtggtcagaaattctcatactatcatgcagatt
caatgtaaagggggcctaaagggggccttgcagttcaacagccatacattacatcagtgg
ctcaaagacaagaataaaggagaaatatacgatgcagccattgatttgtttacacgttca
tgtgctggatactgcgtggctaccttcattttgggaatcggtgaccggcacaatagtaat
atcatggtgaaggatgatggacaattatttcatatagactttggacactttttggatcac
aaaaagaagaaatttggttataaacgagagcgtgtgcccttcgtcttgacacaagatttc
ttgattgtaataagcaaaggagcccaagaatgcacaaagacgagagaatttgagagattt
caggaaatgtgctataaggcgtacttagctattcggcaacatgccaatctcttcatcaat
cttttctccatgatgcttggctctggaatgcccgaactacaatcatttgatgatattgca
tacattcgaaagaccctggccttggataaaactgagcaggaggctttggagtatttcatg
aagcagatgaatgatgctcatcatgggggctggacaaccaaaatggattggattttccat
acaataaagcagcacgctttgaactga

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