KEGG   Monodelphis domestica (gray short-tailed opossum): 100013712
Entry
100013712         CDS       T01031                                 
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase 1
  KO
K13240  nitric-oxide synthase, brain [EC:1.14.13.39]
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo00220  Arginine biosynthesis
mdo00330  Arginine and proline metabolism
mdo01100  Metabolic pathways
mdo04020  Calcium signaling pathway
mdo04145  Phagosome
mdo04371  Apelin signaling pathway
mdo04713  Circadian entrainment
mdo04730  Long-term depression
mdo04926  Relaxin signaling pathway
mdo04970  Salivary secretion
mdo05010  Alzheimer disease
mdo05014  Amyotrophic lateral sclerosis
mdo05022  Pathways of neurodegeneration - multiple diseases
mdo05410  Hypertrophic cardiomyopathy
mdo05412  Arrhythmogenic right ventricular cardiomyopathy
mdo05414  Dilated cardiomyopathy
mdo05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    100013712 (NOS1)
   00330 Arginine and proline metabolism
    100013712 (NOS1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    100013712 (NOS1)
   04020 Calcium signaling pathway
    100013712 (NOS1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    100013712 (NOS1)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100013712 (NOS1)
  09154 Digestive system
   04970 Salivary secretion
    100013712 (NOS1)
  09156 Nervous system
   04730 Long-term depression
    100013712 (NOS1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100013712 (NOS1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100013712 (NOS1)
   05014 Amyotrophic lateral sclerosis
    100013712 (NOS1)
   05022 Pathways of neurodegeneration - multiple diseases
    100013712 (NOS1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100013712 (NOS1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100013712 (NOS1)
   05414 Dilated cardiomyopathy
    100013712 (NOS1)
   05416 Viral myocarditis
    100013712 (NOS1)
Enzymes [BR:mdo01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     100013712 (NOS1)
SSDB
Motif
Pfam: NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2
Other DBs
NCBI-GeneID: 100013712
NCBI-ProteinID: XP_001362705
Ensembl: ENSMODG00000015380
Position
3:complement(505372778..505643082)
AA seq 1430 aa
MEDHMFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGRPLVDLSYEGALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTQPLGPATKAVDLSHQAVPSKDQPPGPDSAVALQSVPQYSRENGQGDNSLAQTNGMLP
DRKGEDPTKKTTLTSLHGGGESNDLLREIQPVLNLLTSGKKEINGGGSLKVETKDAEVQA
DRDLEGKSHKPLPLGMENDRVFNDLWGKNNMPVVLNNPYSEKEQPPTSGRQSPTKNGSPT
KCPRFLKVKNWETDVVLNDTLHLKSTLNTACTGQICMGSIMFPSQHIRKPEDVRTKEQLF
PLAKEFIDQYYSSIKRFGSKAHTDRLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC
VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
NSQLIRYAGYKQPDGSILGDPANVEFTDICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
IPPELVLEVPIRHPKFTWFKELGLKWYGLPAVSSMLLEIGGLEFSACPFSGWYMGTEIGV
RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVH
EERKSYKVRFNSVSSYSDARKSSSDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAF
GHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANN
SLISNDRSWKRNKFRLTYVAEAPELTLGLYSIHKKRVSAARLLSRQNLQSPNSSRSTIFV
RLHTNGNQELQYQPGDHLGVFPGNHEDMVNALIDRLEDAPPANQLVKVELLEERSTALGV
ISNWTDERRIPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEY
EEWKWGKNPTIVEALEEFPSVQMPSTLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAVV
SYRTGDGDGPIHHGVCSSWLNRIQPEEVVPCFVRGAPSFHLPRDPQVPCILVGPGTGIAP
FRSFWQQRLFDIQHKGMTPCHMILVFGCRQSKIDHIYKEETLQAKNKGVFRELYTAYSRE
PDKPKKYVQDALQEQLADTVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMIQQGGLSPE
EAGVFISKLRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDE
NT seq 4293 nt   +upstreamnt  +downstreamnt
atggaagaccacatgtttagcgttcagcaaatccaacccaacgtcatttctgtaagactg
ttcaaacgcaaagtaggaggcttaggcttcctggtgaaagaacgggttagcaagccccct
gtgattatctctgatctgatccggggtggggcagctgaacagagtggtctcatccaagca
ggagatatcatccttgcggtcaatggccggcccttggtggatctgagctatgagggtgcc
ctggaggttctgaggggcattgcctcagagactcatgtggtcctcatcctgaggggccct
gagggcttcactactcacctggagactacattcactggtgatgggacacccaagaccatc
cgagtgacccaacccctaggcccagccaccaaagcagtggacctgtctcaccaggctgtg
cccagtaaagatcagcctccagggccagacagtgctgtggctctccagagtgtgccccag
tactccagggaaaatggtcaaggagacaattccctggcacaaaccaatggcatgttacct
gaccggaaaggtgaggaccccacaaagaaaactaccttgaccagcctgcatggtggtgga
gaaagcaatgaccttctccgagagatccagccagtgctgaacctgctgaccagtggcaag
aaggaaatcaatggaggagggtcactcaaggtagagacaaaggatgcagaagtccaggca
gacagagacttggaaggaaagtcccataagcctcttccacttgggatggagaacgatcgt
gtcttcaatgacctgtgggggaagaacaacatgcctgtcgtcttgaacaacccatattca
gaaaaggagcagcccccaacctcgggaagacagtcaccaaccaagaatggcagccctacc
aaatgtcctcgatttctcaaagtcaagaactgggaaacagatgtggtcctcaatgacaca
ctccacctcaagagcaccttgaacacagcttgcactgggcagatctgcatgggttccatc
atgttcccctcccaacacatacggaagcctgaggatgtccggactaaagagcagctcttt
cccttggccaaagagttcattgatcaatactactcatctataaagagattcggctccaaa
gcccacactgatagactggaagaagtgaataaggagatagaaaccaccagcacctatcag
ctgaaggataccgagctgatctatggagccaagcatgcctggagaaatgcttctcgctgt
gtgggcaggatccagtggtccaagctacaggtgtttgatgcacgagactgtaccacagcc
catgggatgttcaactacatctgtaatcatgtcaagtacgccacgaacaaagggaacctc
aggtctgccatcaccatctttccccagcggacagatggcaagcatgacttcagagtctgg
aactcacagctcatcagatacgcaggctataagcagcctgatggcagcatcctaggagac
cccgccaacgtggagttcacagatatctgcattcagcaaggttggaagcctccaagagga
cgtttcgacgtcctgccgctcctgctccaggccaacggcaatgacccagagctgttccag
attcctccagagctggttttggaagtacccatcagacatcccaagttcacctggttcaag
gaactggggctcaagtggtacggtctgccagctgtatccagcatgcttctggagattggt
ggcctcgagttcagcgcttgcccattcagcggctggtacatgggcactgagatcggtgtc
cgtgattactgtgacaactcccgctataacattctcgaggaagtggccaaaaagatgaat
ttggatatgagaaagacttcctccctgtggaaggaccaagcactggtggagatcaacatt
gctgtgctctacagtttccagagtgacaaagtgacaattgttgaccaccattcagccacc
gagtccttcatcaagcacatggagaacgagtaccgctgccgagggggatgcccggctgac
tgggtctggatcgttccccccatgtctggcagcatcacacccgtcttccaccaggaaatg
ctcaactatcgactcacgccatccttcgagtaccagccggatccatggaacactcatgtc
tggaagggtactaatgggacccccacaaaaaggagagccattggcttcaagaagttggct
gaagctgtcaagttctcagccaagctgatgggtcaggccatggccaaaagagtcaaagcc
accattctctatgccactgagacaggcaaatctcaagcctatgcaaagaccttatgtgaa
atcttcaaacatgccttcgatgctaaggtcatgtccatggaagaatatgacatcgtacac
ctggaacatgagacgctggtcttggtggtcaccagcacctttggcaatggagaccctcca
gagaatggggagaaatttggctgtgctttgatggaaatgaggcacccgaactccgtgcac
gaggagaggaagagctacaaggtccgtttcaacagcgtctcctcatattcagatgcccga
aaatcttccagcgatggaccagacctgagagacaactttgagagtgctgggcccctggcc
aatgtgagattctcggtgtttggtcttggctcaagggcctacccccacttctgtgccttt
ggccatgcagtggacaccctcttagaagaactcggaggggagcgcatcctgaagatgagg
gaaggagatgagctctgtggccaggaagaggcctttaggacctgggccaagaaagtcttc
aaggcagcctgtgatgtgttctgcgtgggggatgatgtcaacattgagaaagccaacaat
tccctcatcagtaatgaccgaagttggaagagaaacaagttccggctgacctacgtggct
gaagctccagagctcacactcggcctatacagcatccacaaaaaacgagtgtcggctgcc
cggcttctcagtcgccagaatctccagagccctaattccagccgatccaccatctttgtt
cgcctgcacaccaacgggaaccaggagttgcagtaccagcccggggaccatctgggcgtg
ttccctggcaaccatgaggacatggtgaatgccctgatcgatcgcctggaggacgcccct
cctgccaaccagctggtgaaggtggagcttctggaggagaggagcacagctctgggcgtc
atcagcaactggacggatgagcggcgcatcccgccctgcaccatcttccaggcctttaag
tactacctggacatcacgacgccccccacgcccctgcagctgcagcagttcgcctccctg
gccaccagcgagaaggagaagcagcggctgctggtcctcagcaagggcttacaggagtac
gaggaatggaagtggggcaagaatcccaccatcgtggaggccctggaggaattcccgtcc
gtgcagatgccgtccaccctcctgctgacccagctgtccctgctgcagccccgctactac
tccatcagctcgtccccagacatgtaccctgacgaggtgcacctgaccgtggccgtcgtg
tcctaccgcaccggagatggggatggcccgatccaccatggcgtctgctcttcctggctc
aaccggatccagccggaggaggtggtgccctgcttcgttcgaggcgctcccagcttccac
ctgccccgggacccccaggtgccctgtatcctggttggcccaggcacgggcatcgcccct
ttccggagcttctggcagcagcggctcttcgatatccagcacaaaggaatgactccatgt
cacatgatcctggtctttggatgtcggcagtccaagattgaccacatttacaaagaggaa
accttacaggccaagaacaagggggtcttcagagagctgtacacagcatattcccgagag
ccagacaaaccaaagaaatatgtacaggatgccttacaggaacagctggcagacactgtg
tacagagccctgaaggaacaagggggacacatctatgtgtgtggggatgtcacgatggcg
gccgatgtcctgaaagccatccagcgcatcatgatccagcagggcgggctctcaccagag
gaggctggggttttcattagcaaactgagggatgacaaccgctaccatgaggacatattt
ggggtcaccctgcgcacatatgaagtgaccaaccgccttagatctgagtccattgccttc
attgaagagagcaagaaggacactgatgagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (7)   
   Pfam (7)   
All databases (70)   

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