KEGG   Monodelphis domestica (opossum): 100014343Help
Entry
100014343         CDS       T01031                                 

Gene name
MAPK8
Definition
mitogen-activated protein kinase 8
Orthology
K04440  
c-Jun N-terminal kinase [EC:2.7.11.24]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
cAMP signaling pathway
FoxO signaling pathway
Protein processing in endoplasmic reticulum
Wnt signaling pathway
Osteoclast differentiation
Focal adhesion
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Adipocytokine signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Salmonella infection
Pertussis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Pathways in cancer
Colorectal cancer
Pancreatic cancer
Brite
KEGG Orthology (KO) [BR:mdo00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100014343 (MAPK8)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100014343 (MAPK8)
   04010 MAPK signaling pathway
    100014343 (MAPK8)
   04012 ErbB signaling pathway
    100014343 (MAPK8)
   04310 Wnt signaling pathway
    100014343 (MAPK8)
   04668 TNF signaling pathway
    100014343 (MAPK8)
   04068 FoxO signaling pathway
    100014343 (MAPK8)
   04024 cAMP signaling pathway
    100014343 (MAPK8)
 Cellular Processes
  Cellular commiunity
   04510 Focal adhesion
    100014343 (MAPK8)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    100014343 (MAPK8)
   04621 NOD-like receptor signaling pathway
    100014343 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    100014343 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    100014343 (MAPK8)
  Endocrine system
   04910 Insulin signaling pathway
    100014343 (MAPK8)
   04920 Adipocytokine signaling pathway
    100014343 (MAPK8)
   04912 GnRH signaling pathway
    100014343 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    100014343 (MAPK8)
   04917 Prolactin signaling pathway
    100014343 (MAPK8)
  Nervous system
   04728 Dopaminergic synapse
    100014343 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    100014343 (MAPK8)
   04722 Neurotrophin signaling pathway
    100014343 (MAPK8)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100014343 (MAPK8)
  Development
   04380 Osteoclast differentiation
    100014343 (MAPK8)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100014343 (MAPK8)
   05210 Colorectal cancer
    100014343 (MAPK8)
   05212 Pancreatic cancer
    100014343 (MAPK8)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100014343 (MAPK8)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100014343 (MAPK8)
  Infectious diseases
   05132 Salmonella infection
    100014343 (MAPK8)
   05133 Pertussis
    100014343 (MAPK8)
   05152 Tuberculosis
    100014343 (MAPK8)
   05164 Influenza A
    100014343 (MAPK8)
   05161 Hepatitis B
    100014343 (MAPK8)
   05160 Hepatitis C
    100014343 (MAPK8)
   05168 Herpes simplex infection
    100014343 (MAPK8)
   05169 Epstein-Barr virus infection
    100014343 (MAPK8)
   05145 Toxoplasmosis
    100014343 (MAPK8)
   05142 Chagas disease (American trypanosomiasis)
    100014343 (MAPK8)
Enzymes [BR:mdo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100014343 (MAPK8)
Protein kinases [BR:mdo01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   100014343 (MAPK8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
1
AA seq 427 aa AA seqDB search
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPAPLGAAVISGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLETSA
GPLGCCR
NT seq 1284 nt NT seq  +upstreamnt  +downstreamnt
atgagtagaagcaagcgtgacagtaatttctatagtgtagagattggagattctacattt
actgtactgaaacggtatcagaatttaaaaccaataggctcaggggcccagggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagccgacca
tttcagaatcaaacccatgccaagcgggcttatagagagcttgttctcatgaaatgtgtt
aatcacaaaaatataattggcctcttgaatgtgttcacaccacagaagtctctagaagaa
tttcaggatgtttacatagtcatggagcttatggatgcaaatctttgccaagtcattcaa
atggagctagaccatgaacgaatgtcctaccttctctatcaaatgctgtgtggaatcaag
caccttcactctgctggaattatccatcgagacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccagaactgcaggaactagtttt
atgatgacaccttatgtagtgactcgttactacagagcacccgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacaa
cttggaacaccatgccctgagttcatgaagaaattgcaaccaacagtaaggacatatgtg
gagaatagacctaaatatgctggatatagctttgagaagctcttcccagatgtacttttc
ccagctgactcagagcacaacaaacttaaagctagtcaggcaagggatttgttgtcaaaa
atgctggttatagatgcatctaaaagaatctctgtggatgaagctctccagcacccatat
atcaacgtctggtatgatccttcagaagcagaggcacctccaccaaagataccggacaag
cagttggatgaaagggagcacacaatagaagagtggaaagaattgatatacaaggaagtt
atggacttggaggaaagaactaagaatggagttatacggggtcagccggctcctttaggt
gcagcagtgattagtggctctcaacatccatcttcatcatcgtctgtcaatgatgtgtct
tcaatgtcaacagatccaacattggcctctgatacagatagcagtctagaaacatcagct
ggacctctgggctgctgtagatga

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