KEGG   Monodelphis domestica (opossum): 100023604Help
Entry
100023604         CDS       T01031                                 

Gene name
PRF1
Definition
perforin 1 (pore forming protein)
Orthology
K07818  
perforin 1
Organism
mdo  Monodelphis domestica (opossum)
Pathway
Natural killer cell mediated cytotoxicity
Type I diabetes mellitus
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mdo00001]
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100023604 (PRF1)
 Human Diseases
  Immune diseases
   05320 Autoimmune thyroid disease
    100023604 (PRF1)
   05330 Allograft rejection
    100023604 (PRF1)
   05332 Graft-versus-host disease
    100023604 (PRF1)
  Cardiovascular diseases
   05416 Viral myocarditis
    100023604 (PRF1)
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    100023604 (PRF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
1
AA seq 559 aa AA seqDB search
MVWSSSSSLLFLLLILLQLLQPTPAPCHTATRAECHRQEIFVPGWGLAGEGIDITTLHRT
GYFPVDTHRFKRPDGTCTLCRNDLQEGQLQRLPLAITDWRSQSPKCQRNVVKTEASSVVE
VAAQASKRIKNDWKVGLDVQPNPKVNVHMSMSGSHSKEAQFAAEKKQQDEYSFKGELVQC
HNYRFHLVEKPPLTRAFIQAVRALPRQFNASTRVHYFRLIKNYGTHFLKSLELGGKVTDV
TALRTCKLSLDGLKADEVSSCLKVEAAVTVGTAVSTADVENCMEKKKNHHIQGSFHTTYN
ERHVDVEGGILSGGSIDLLFSDQNGAEKFTEWMNTLSSNPGLLAYTLDPLHFLLGSKNPQ
RVELRKAVSDYILSRARWQNCNKPCPPGQKKSPQNPCHCVCQASTLTNGDCCPRERGLAH
LEVTGLSARNLYGDIFSLTDGYIKAFFGNKELRTYVVWNNNNPKWDQNLDFGAVSLMAGG
PLRLQVWDADHGWDDDLLGSCDRVPVAGGRKEQCHLNHGFLTFHYQVTCAPYLKGHKCLE
YAPHRALGEPVGNRSGAVW
NT seq 1680 nt NT seq  +upstreamnt  +downstreamnt
atggtatggtcctcctcctcttccctcctcttcctcctgctcatccttctccagctgctc
cagcctacaccagccccctgccacacggccacccgtgctgagtgccaccgccaagagata
tttgtacccggctggggtttggcaggggaaggtatagatatcaccaccctgcaccgaact
ggctacttccccgtggatacccatagattcaagcgtcctgatggcacctgcaccctatgc
cgaaatgatctgcaggagggtcagctccagcgccttcccttggctatcacagactggcgc
agccagagtcctaagtgtcagcggaatgtagtcaagactgaggcttcctctgtcgtggaa
gtggctgcccaggcctccaagagaatcaagaatgactggaaggtgggcctggacgtccag
cccaatcccaaagtcaatgtacatatgtccatgtcgggctcccactccaaagaagcccaa
ttcgcagctgaaaaaaaacagcaggatgagtacagtttcaagggtgagttggttcagtgt
cataactacagatttcacctggtagagaagcccccgctgactcgagcgttcattcaggct
gtcagggcactgcctcgccaatttaatgcctccactcgagtccactattttaggctcatc
aagaattatggcacccactttctcaagtccttggagctgggggggaaggtcacggatgtc
acggcccttcgcacatgcaagctgtctctggatgggctcaaggccgacgaggtgagctcc
tgcctcaaagtagaggcagccgttactgtggggactgctgttagcacagcggatgttgag
aactgcatggagaagaagaagaaccaccacatccagggttccttccataccacctacaat
gagcgccatgtggacgtagagggaggtattttgagtgggggctcaatcgacctgctcttc
tcagatcagaatggggccgagaagttcacagaatggatgaacaccctctccagtaacccc
ggccttttggcctatactctggaccccctgcacttcctcctgggatctaagaatccccaa
cgggtggagttaagaaaggctgtgagtgactacatactcagcagagcccggtggcagaac
tgtaataagccatgccctccagggcaaaagaaaagcccacaaaacccctgccactgcgta
tgccaggcatccaccctcaccaatggcgactgctgcccccgggagagagggctggcccat
cttgaagtgactggcttgagtgccaggaacctatacggagacatcttctccttaactgat
ggctacataaaggccttcttcggtaacaaggaactgaggacctatgtggtgtggaacaac
aacaatcccaaatgggaccagaatctggacttcggggccgtgtcgctgatggctggggga
cccttgaggcttcaggtatgggatgcagaccacggttgggacgatgaccttctgggctct
tgtgaccgtgtgccggtggcaggaggacggaaggagcaatgtcatttaaatcatggcttc
ctaacattccactaccaagtgacatgcgccccatatctcaagggccacaaatgtctagag
tatgcccctcatagagctcttggggagccagtgggaaaccggagtggagccgtgtggtaa

DBGET integrated database retrieval system