KEGG   Monodelphis domestica (gray short-tailed opossum): 100026418
Entry
100026418         CDS       T01031                                 
Symbol
ERN1
Name
(RefSeq) endoplasmic reticulum to nucleus signaling 1
  KO
K08852  serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
Organism
mdo  Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo04140  Autophagy - animal
mdo04141  Protein processing in endoplasmic reticulum
mdo04210  Apoptosis
mdo04932  Non-alcoholic fatty liver disease
mdo05010  Alzheimer disease
mdo05012  Parkinson disease
mdo05014  Amyotrophic lateral sclerosis
mdo05016  Huntington disease
mdo05017  Spinocerebellar ataxia
mdo05022  Pathways of neurodegeneration - multiple diseases
mdo05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mdo00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100026418 (ERN1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100026418 (ERN1)
  09143 Cell growth and death
   04210 Apoptosis
    100026418 (ERN1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100026418 (ERN1)
   05012 Parkinson disease
    100026418 (ERN1)
   05014 Amyotrophic lateral sclerosis
    100026418 (ERN1)
   05016 Huntington disease
    100026418 (ERN1)
   05017 Spinocerebellar ataxia
    100026418 (ERN1)
   05022 Pathways of neurodegeneration - multiple diseases
    100026418 (ERN1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100026418 (ERN1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100026418 (ERN1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mdo01001]
    100026418 (ERN1)
Enzymes [BR:mdo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100026418 (ERN1)
Protein kinases [BR:mdo01001]
 Serine/threonine kinases: Other
  IRE family
   100026418 (ERN1)
SSDB
Motif
Pfam: Ribonuc_2-5A Pkinase PK_Tyr_Ser-Thr PQQ_2 PQQ Pkinase_fungal Kdo APH Portal_Gp20
Other DBs
NCBI-GeneID: 100026418
NCBI-ProteinID: XP_007483088
Ensembl: ENSMODG00000009349
Position
2:complement(211327740..211454217)
AA seq 1006 aa
MPVPPRRLLQLLALLLLPLPGPGSFASTSTVTLPETLLFVSTLDGSLHAVSKRTGSTKWT
LKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGI
LYMGKKQDIWYVVDLMTGEKQQTLSSAFAESLCPSTSLLYLGRTEYTITMFDTKSRELRW
NATYFDYAATVPEEDVEYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWHRE
GLQKVMHTNVGVETLRYLTFMSGEVGRITKWKYPFPKETETKSKLTPTLYVGRYSTSLYA
SPSMVHEGVAIVPRGSAFPQLEGPQTDGVTIKSNEECVITPSVEFGFGFKGKNKLNYWTN
YWLLIGHHEIPLSASTTVLEKFPNKLPRHPENVIPADSEKSFDEKVIKMVDRHTEEPTPT
TRQDIEFTRTPVKTEAAVDSMLKDMATIILCTFLLIGWVAFVITYPMSMHQQQQLQHQQF
QRQLEERIQLLQQQQLPFQPPSDLSQDSDFLDVSAGLHSESSAPSSPNMSPKGSNHSQHS
SNSAFKVSSIVAAEQDENGKAMCYFLRYIFCHRDQLGKINLSEAKFQLTPAFYPLHHLAA
HPYFQGANLIPFYPFSRGTFDNRAVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCT
ERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAYLHSLSIVHRDLKP
HNILLSMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENP
TYTVDIFSAGCVFYYVISDGNHPFGKSLQRQANILLGAYSLDCLHPEKHEDIVAHELIEK
MIAMDPQKRPSAKHVLKHPFFWGLEKQLQFFQDVSDRIEKEALDGPIVKQLERGGRAVVK
MDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPEAVQETLGSIPDDFVR
YFTSRFPHLLSHTYRAMELCSHERLFQPYYFQEATELGPLVTNDGL
NT seq 3021 nt   +upstreamnt  +downstreamnt
atgccggtcccgccgcgccggctcctgcagctgctggcgctgctgctcttgcccctgccg
ggtcccgggagttttgcaagcaccagcactgtgacccttcctgagaccctgttgtttgtt
tcaaccttggatggaagcctgcatgccgtgagcaagaggacgggatcaacaaaatggact
ttaaaagaagatccagtcctgcaggtccccacccatgttgaagagcctgctttcctacca
gaccccaatgatggaagcctgtacacacttggtgggaagaacaatgaaggtctgacgaaa
cttccctttaccattccagaattggtgcaggcatccccgtgtcgaagttcagatgggatt
ctctacatgggtaaaaagcaggatatttggtatgtcgtcgacctcatgactggggagaag
cagcagactttatcttcagcatttgcagaaagcctctgtccatccacctctcttctgtat
cttggacgtacagagtacaccatcaccatgtttgatacaaagagtcgagagcttcggtgg
aatgctacctattttgactacgcagccactgtaccagaggaggatgtggaatacaagatg
tcccactttgtgtccaatggggatgggctggtggtgactgtggacagtgagtctggcgat
gtcttgtggattcagaattatgcctcgccagtggtggccttctacatctggcatcgagaa
ggcctgcagaaggtgatgcacaccaatgtcggggtggagacactgcgctatctgaccttc
atgtctggagaggtgggacggatcaccaagtggaaataccccttcccaaaggagaccgag
accaagagcaaactgacgcccaccctctacgttgggaggtattccaccagcctgtatgcc
tccccatcaatggtacatgaaggagttgctattgtgcctcgaggtagtgcctttccccaa
ctggaaggcccccagacagacggtgtcacaatcaaaagtaatgaagagtgtgtgatcacc
cccagcgtagagtttggttttggattcaaaggaaagaacaaactcaactactggaccaat
tattggcttctcataggacatcatgagatccccctgtctgcttccaccacagtcctggag
aaattccccaacaaactgccccggcatcctgaaaatgtgatccctgctgattccgaaaag
agttttgatgagaaggttatcaaaatggttgaccggcacacagaagaaccaactcctact
actcgtcaagatattgaattcactcgaaccccagtaaaaacagaggctgctgtagactcc
atgttgaaggacatggctacaatcatcctgtgtaccttccttctcattggatgggtcgcc
ttcgtcatcacctacccaatgagcatgcaccagcagcagcagctccagcaccagcagttt
cagaggcagctggaagagaggatccagctgttgcaacaacagcagctccctttccagcct
ccgagtgacctgtctcaggactcggatttcctggatgtctctgctggtttgcactccgag
agctcagcccccagcagtcccaacatgtcccccaagggctccaaccactctcagcattcc
agcaactcagctttcaaggtcagcagcatcgtggctgctgagcaagatgagaatggtaaa
gccatgtgttattttctacgttacatcttttgtcatcgagaccagctaggaaaaataaat
ttgtctgaggccaaatttcaactcacacctgccttctatccattgcaccacctagctgcc
catccatatttccaaggggcaaaccttatacctttttaccctttttccagagggacgttt
gacaatagagctgtggcagtgaaaaggatactcccagagtgcttcagttttgcagaccgg
gaggtgcagctgcttcgggaatcagacgagcatcccaatgtgattcgctatttctgcaca
gagcgagatcgtcaattccaatacattgccattgaactgtgtgcggccactttgcaagag
tacgtggaacagaaggactttgcccaccttggcttagaacccatcaccttgctgcagcag
acaacctcgggtcttgcttaccttcactccctcagcattgttcacagagacctgaaaccc
cacaacatcctcctgtccatgcccaatgcacatggcaagatcaaggctatgatctctgac
tttggcctctgcaagaagctggctgtaggaaggcacagtttcagtcgccgctctggggta
ccaggtaccgagggatggattgccccagagatgctgagtgaagattgcaaagagaatccg
acttacactgtggacattttctctgcgggctgtgtcttttactatgtgatatctgatggc
aaccacccatttggcaagtccctgcagcggcaagccaacatccttcttggcgcctacagc
cttgactgtttgcacccagagaagcacgaagacatcgttgctcatgaactaatagaaaaa
atgattgctatggatcctcagaaaaggccctcagccaagcatgtactgaaacacccattc
ttctggggcttagaaaagcagctgcaattctttcaggatgtgagtgaccgaatagagaag
gaggccctagatggccccatagtgaagcagttagaaagaggagggagagcggtggtcaaa
atggactggagggaaaacataactgttccactccagacagatcttcgaaaattcaggacc
tataaagggggttctgtaagagatcttctccgtgctatgagaaataagaagcaccactac
cgggagcttccggaggctgtgcaggagaccctgggctctatccctgatgattttgtccgt
tatttcacatcacggttcccccatctcctctcccacacctaccgagccatggaactatgt
agccatgagagactcttccagccttactatttccaagaggccacagaactgggaccccta
gtcacaaacgacggtctctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (9)   
   Pfam (9)   
All databases (49)   

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