KEGG   Monodelphis domestica (opossum): 100031263Help
Entry
100031263         CDS       T01031                                 

Gene name
PLCB3
Definition
phospholipase C, beta 3 (phosphatidylinositol-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mdo00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100031263 (PLCB3)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100031263 (PLCB3)
   04310 Wnt signaling pathway
    100031263 (PLCB3)
   04020 Calcium signaling pathway
    100031263 (PLCB3)
   04070 Phosphatidylinositol signaling system
    100031263 (PLCB3)
   04022 cGMP - PKG signaling pathway
    100031263 (PLCB3)
 Cellular Processes
  Cellular commiunity
   04540 Gap junction
    100031263 (PLCB3)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100031263 (PLCB3)
   04062 Chemokine signaling pathway
    100031263 (PLCB3)
  Endocrine system
   04911 Insulin secretion
    100031263 (PLCB3)
   04912 GnRH signaling pathway
    100031263 (PLCB3)
   04915 Estrogen signaling pathway
    100031263 (PLCB3)
   04921 Oxytocin signaling pathway
    100031263 (PLCB3)
   04918 Thyroid hormone synthesis
    100031263 (PLCB3)
   04919 Thyroid hormone signaling pathway
    100031263 (PLCB3)
   04916 Melanogenesis
    100031263 (PLCB3)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100031263 (PLCB3)
   04270 Vascular smooth muscle contraction
    100031263 (PLCB3)
  Digestive system
   04970 Salivary secretion
    100031263 (PLCB3)
   04971 Gastric acid secretion
    100031263 (PLCB3)
   04972 Pancreatic secretion
    100031263 (PLCB3)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100031263 (PLCB3)
  Nervous system
   04724 Glutamatergic synapse
    100031263 (PLCB3)
   04725 Cholinergic synapse
    100031263 (PLCB3)
   04728 Dopaminergic synapse
    100031263 (PLCB3)
   04726 Serotonergic synapse
    100031263 (PLCB3)
   04720 Long-term potentiation
    100031263 (PLCB3)
   04730 Long-term depression
    100031263 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    100031263 (PLCB3)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100031263 (PLCB3)
  Environmental adaptation
   04713 Circadian entrainment
    100031263 (PLCB3)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100031263 (PLCB3)
   05016 Huntington's disease
    100031263 (PLCB3)
  Infectious diseases
   05146 Amoebiasis
    100031263 (PLCB3)
   05142 Chagas disease (American trypanosomiasis)
    100031263 (PLCB3)
   05143 African trypanosomiasis
    100031263 (PLCB3)
Enzymes [BR:mdo01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100031263 (PLCB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1064 aa AA seqDB search
ILKMFSADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIG
AKGKPYLTLEQLLDFVNQKQRDPRLNEVLYPPLRPAQARLLIEKYEPNQQFLERDQMSME
GFSRYLGGEENSVLPPEALDLSNDMTQPLSSYFINSSHNTYLTAGQLAGASSVEMYRQTL
LWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPFPVILSFEN
HVDSAKQQAKMAEYCRTIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPP
LSPSDGSVRKRPLEQSNSALSESSVATEPPSPQLGSPSSEGCSTLSNGEDHVGCNPEPRK
SIDREAESEEEEEEEPADPKKNSTDEGTASSEVNATEEMSTLVNYIEPVKFKSFEVARKR
NKCFEMSSFVETKALEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNAGCQL
VALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEGIVDGIVANALRVK
VISGQFLSDRKVSIYVEVDVFGLPADTRRKYRTRPSQGNSFNPVWDEEPFDFPKVVLPTL
ASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLRNEANQPLCLPALLIYTEASDYIPDD
HQDYAEALFNPIKHVSLMDQRSKQLAALIGESEAAPETPEERPSRQLGPQLSTGSVQSPQ
EPGASRTHGPSTSPTSPSISRPGQCDELIASLLGEVSVTPLAELRVHKALLKLRNRQERD
LRELQKKQQRKAAAFLRRLHSHLAQYRADMEKRRKQQSQAGVLEEEEGEEMRSYRELQKK
QLQSLLDLREAQADAEAERRQEHLRQAQHRLREIVLETHTTQLKKLKETSEKEKKELQKI
LDRKRHNSISEAKIREKHKKEAELTEINRRHITESVNAIRRLEEAQKQRQERLVAGQLQV
QQQLEEEEPKVASRLAQECQAQRARLPQEIRQSLWGELPVEQAAEEEEEEDLAAGDGPSL
GTVSGHTLGRASNGHALGGRASNGHAQGSGSGVDCERQEENTQL
NT seq 3196 nt NT seq  +upstreamnt  +downstreamnt
catccttaaaatgttctctgcggacaagaagcgggtggagacggcgctggagtcctgcgg
cctcaattttaacaggagcgagtcgatccggccagacgagttttccctggagatctttga
gagattcctcaataaactgtgtctgcggcctgacatagacaagatcctgctggagattgg
ggccaaggggaagccctacctgaccctggagcagctcctggactttgtcaaccagaagca
gcgcgacccccggctgaacgaggtcctgtacccgccgctgcgcccggcccaggcccgcct
gctcatcgagaagtacgagcccaaccagcagttcttggagcgagaccagatgtccatgga
aggcttcagccgctacctgggcggggaggagaacagcgtcctgccgcccgaagccctgga
cctgagcaacgacatgacgcagcccctgagctcctatttcatcaactcctcccacaacac
ctacctcacagcggggcagctggcaggggcctcgtcggtggagatgtaccggcagaccct
gctctggggttgccgctgcgtggagttggatgtgtggaaaggccggccgcccgaggagga
gcccttcatcacccacggcttcaccatgaccacggaagtgcctctgcgggacgtgctgga
ggcgatcgcggaaacggccttcaagacgtcccccttccccgtcatcctctccttcgagaa
ccacgtggactcggcgaaacagcaggccaagatggcggagtactgccgcaccatctttgg
ggacgcgctgctcatcgacccgctggataagtacccgctggccccaggagtccccctgcc
cagccctcaggacctgatgggccgaatcctcgtgaagaataagaagcggcaccggccgcc
cctgagcccgtcagacggctcggtgcgcaagcggcccttggagcagagtaactcggcctt
gagcgagagttccgtggccacggagcccccctccccgcagctcggctcccccagctccga
gggctgttccactctgagcaacggagaagatcacgtgggctgcaaccccgaaccccgcaa
gtccatcgaccgagaggcagagagtgaagaagaggaggaggaagaaccggccgaccccaa
gaagaacagcacagacgagggcacggccagcagcgaggtgaacgccacggaggagatgtc
cactctggtcaattacatcgagccggtcaagttcaagtcctttgaggtggcccggaagcg
gaacaagtgctttgagatgtcatcctttgtggagaccaaggccctggagcagctcaccaa
gagccccatggaatttgtggaatacaacaagcagcagctcagccgcatctaccccaaggg
cacccgggtcgactcctccaactacatgcctcagctcttctggaacgcaggctgccagct
cgttgccctcaacttccagacactggacctcccaatgcagctgaatgccggcgtgtttga
gtacaacgggcgcagtggctacctgctcaagccagagttcatgcggcgcccggacaagtc
ttttgaccctttcacggaaggcatcgtggacggcatcgtggccaatgccctccgggtcaa
ggtgatctcgggccagtttctatcagacaggaaggtcagcatctatgtagaggtggatgt
cttcggccttcctgcggacacacgtcgcaaataccgcactcggccctcacagggcaactc
ctttaacccggtgtgggacgaggagccctttgacttccccaaggtggtgctgcccacctt
ggcctccctccgcattgcggcctttgaggaagggggcaagtttgtgggacaccgaatcct
gccagtgtccgccattcgctcagggtaccattacatctgcctgaggaatgaggccaatca
gcccctgtgtctgcctgccctgctcatctacacagaagcttctgactacatccctgatga
tcaccaggactatgccgaggctttgttcaaccccatcaaacatgtcagcctcatggacca
gagatcaaagcaattggcagctctgattggtgagagtgaggctgctcccgagaccccaga
ggagaggccttctcgccagctagggccccagctgtccacgggctccgtccagagccccca
ggaacctggagcctcccgcacccatggcccttccacctcccccaccagcccttccataag
cagaccaggtcagtgcgatgagctcatcgccagcctcctgggagaggtatctgtgacccc
cttggcggagctccgggttcacaaggccctgctgaagctccggaaccggcaggagcgaga
cctgcgggagctgcagaagaagcagcagcgcaaggcggcggccttcctacggcgcctcca
cagccacctggcccagtaccgggccgacatggagaagaggcgcaagcagcagtcccaggc
cggggtgctggaggaggaagagggggaagagatgcggagctatcgggagctgcagaagaa
acagcttcagagtctgctggacctgagggaggcccaggccgacgcggaagccgaacgtcg
ccaggaacacctgagacaggcccagcatcgccttcgcgagattgtccttgaaacgcacac
gactcagctgaaaaaactgaaggagacgagtgaaaaggagaagaaggagctgcagaagat
tctggaccggaagagacataatagcatttctgaagccaagatccgggagaagcacaagaa
ggaggcggagctgactgagattaaccggcgtcacatcacggagtcggtcaacgccatccg
gaggctggaggaggcccagaagcagcgccaggagcggctggtggccggccagctgcaagt
ccagcagcagctagaagaggaagagcccaaggtggcctcccggctggcccaggagtgcca
ggcccagcgggcacggctgccacaagagatccgacagagcctgtggggtgagctgccggt
ggagcaggcggcggaggaggaggaggaggaggaccttgctgcaggcgatggtcccagcct
gggcactgtcagcgggcacacgctgggcagagccagcaatgggcacgccctggggggcag
agccagtaatgggcatgcccaggggagtggcagtggtgtagactgtgagaggcaagaaga
gaacacccagctgtga

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