KEGG   Monodelphis domestica (opossum): 100031263Help
Entry
100031263         CDS       T01031                                 

Gene name
PLCB3
Definition
phospholipase C, beta 3 (phosphatidylinositol-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:mdo00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:mdo04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:mdo04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:mdo04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:mdo04070]
Cellular Processes; Cell communication; Gap junction [PATH:mdo04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:mdo04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:mdo04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:mdo04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:mdo04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:mdo04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:mdo04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:mdo04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:mdo04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:mdo04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:mdo04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:mdo04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:mdo04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:mdo04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:mdo04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:mdo04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:mdo04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:mdo04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:mdo04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:mdo04720]
Organismal Systems; Nervous system; Long-term depression [PATH:mdo04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:mdo04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:mdo04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:mdo04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:mdo05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:mdo05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:mdo05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:mdo05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:mdo05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1089 aa AA seqDB search
VNREGRFPVKNILKMFSADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLR
PDIDKILLEIGAKGKPYLTLEQLLDFVNQKQRDPRLNEVLYPPLRPAQARLLIEKYEPNQ
QFLERDQMSMEGFSRYLGGEENSVLPPEALDLSNDMTQPLSSYFINSSHNTYLTAGQLAG
ASSVEMYRQTLLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKT
SPFPVILSFENHVDSAKQQAKMAEYCRTIFGDALLIDPLDKYPLAPGVPLPSPQDLMGRI
LVKNKKRHRPPLSPSDGSVRKRPLEQSNSALSESSVATEPPSPQLGSPSSEGCSTLSNGE
DHVGCNPEPRKSIGERTGGTPVLVLPPDREAESEEEEEEEPADPKKNSTDEGTASSEVNA
TEEMSTLVNYIEPVKFKSFEVARKRNKCFEMSSFVETKALEQLTKSPMEFVEYNKQQLSR
IYPKGTRVDSSNYMPQLFWNAGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMR
RPDKSFDPFTEGIVDGIVANALRVKVISGQFLSDRKVSIYVEVDVFGLPADTRRKYRTRP
SQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYICLR
NEANQPLCLPALLIYTEASDYIPDDHQDYAEALFNPIKHVSLMDQRSKQLAALIGESEAA
PETPEERPSRQLGPQLSTGSVQSPQEPGASRTHGPSTSPTSPSISRPGQCDELIASLLGE
VSVTPLAELRVHKALLKLRNRQERDLRELQKKQQRKAAAFLRRLHSHLAQYRADMEKRRK
QQSQAGVLEEEEGEEMRSYRELQKKQLQSLLDLREAQADAEAERRQEHLRQAQHRLREIV
LETHTTQLKKLKETSEKEKKELQKILDRKRHNSISEAKIREKHKKEAELTEINRRHITES
VNAIRRLEEAQKQRQERLVAGQLQVQQQLEEEEPKVASRLAQECQAQRARLPQEIRQSLW
GELPVEQAAEEEEEEDLAAGDGPSLGTVSGHTLGRASNGHALGGRASNGHAQGSGSGVDC
ERQEENTQL
NT seq 3270 nt NT seq  +upstreamnt  +downstreamnt
gtgaatcgggaggggcgattcccagtgaaaaacatccttaaaatgttctctgcggacaag
aagcgggtggagacggcgctggagtcctgcggcctcaattttaacaggagcgagtcgatc
cggccagacgagttttccctggagatctttgagagattcctcaataaactgtgtctgcgg
cctgacatagacaagatcctgctggagattggggccaaggggaagccctacctgaccctg
gagcagctcctggactttgtcaaccagaagcagcgcgacccccggctgaacgaggtcctg
tacccgccgctgcgcccggcccaggcccgcctgctcatcgagaagtacgagcccaaccag
cagttcttggagcgagaccagatgtccatggaaggcttcagccgctacctgggcggggag
gagaacagcgtcctgccgcccgaagccctggacctgagcaacgacatgacgcagcccctg
agctcctatttcatcaactcctcccacaacacctacctcacagcggggcagctggcaggg
gcctcgtcggtggagatgtaccggcagaccctgctctggggttgccgctgcgtggagttg
gatgtgtggaaaggccggccgcccgaggaggagcccttcatcacccacggcttcaccatg
accacggaagtgcctctgcgggacgtgctggaggcgatcgcggaaacggccttcaagacg
tcccccttccccgtcatcctctccttcgagaaccacgtggactcggcgaaacagcaggcc
aagatggcggagtactgccgcaccatctttggggacgcgctgctcatcgacccgctggat
aagtacccgctggccccaggagtccccctgcccagccctcaggacctgatgggccgaatc
ctcgtgaagaataagaagcggcaccggccgcccctgagcccgtcagacggctcggtgcgc
aagcggcccttggagcagagtaactcggccttgagcgagagttccgtggccacggagccc
ccctccccgcagctcggctcccccagctccgagggctgttccactctgagcaacggagaa
gatcacgtgggctgcaaccccgaaccccgcaagtccatcggtgagaggacgggagggacc
ccagttcttgtcctccccccagaccgagaggcagagagtgaagaagaggaggaggaagaa
ccggccgaccccaagaagaacagcacagacgagggcacggccagcagcgaggtgaacgcc
acggaggagatgtccactctggtcaattacatcgagccggtcaagttcaagtcctttgag
gtggcccggaagcggaacaagtgctttgagatgtcatcctttgtggagaccaaggccctg
gagcagctcaccaagagccccatggaatttgtggaatacaacaagcagcagctcagccgc
atctaccccaagggcacccgggtcgactcctccaactacatgcctcagctcttctggaac
gcaggctgccagctcgttgccctcaacttccagacactggacctcccaatgcagctgaat
gccggcgtgtttgagtacaacgggcgcagtggctacctgctcaagccagagttcatgcgg
cgcccggacaagtcttttgaccctttcacggaaggcatcgtggacggcatcgtggccaat
gccctccgggtcaaggtgatctcgggccagtttctatcagacaggaaggtcagcatctat
gtagaggtggatgtcttcggccttcctgcggacacacgtcgcaaataccgcactcggccc
tcacagggcaactcctttaacccggtgtgggacgaggagccctttgacttccccaaggtg
gtgctgcccaccttggcctccctccgcattgcggcctttgaggaagggggcaagtttgtg
ggacaccgaatcctgccagtgtccgccattcgctcagggtaccattacatctgcctgagg
aatgaggccaatcagcccctgtgtctgcctgccctgctcatctacacagaagcttctgac
tacatccctgatgatcaccaggactatgccgaggctttgttcaaccccatcaaacatgtc
agcctcatggaccagagatcaaagcaattggcagctctgattggtgagagtgaggctgct
cccgagaccccagaggagaggccttctcgccagctagggccccagctgtccacgggctcc
gtccagagcccccaggaacctggagcctcccgcacccatggcccttccacctcccccacc
agcccttccataagcagaccaggtcagtgcgatgagctcatcgccagcctcctgggagag
gtatctgtgacccccttggcggagctccgggttcacaaggccctgctgaagctccggaac
cggcaggagcgagacctgcgggagctgcagaagaagcagcagcgcaaggcggcggccttc
ctacggcgcctccacagccacctggcccagtaccgggccgacatggagaagaggcgcaag
cagcagtcccaggccggggtgctggaggaggaagagggggaagagatgcggagctatcgg
gagctgcagaagaaacagcttcagagtctgctggacctgagggaggcccaggccgacgcg
gaagccgaacgtcgccaggaacacctgagacaggcccagcatcgccttcgcgagattgtc
cttgaaacgcacacgactcagctgaaaaaactgaaggagacgagtgaaaaggagaagaag
gagctgcagaagattctggaccggaagagacataatagcatttctgaagccaagatccgg
gagaagcacaagaaggaggcggagctgactgagattaaccggcgtcacatcacggagtcg
gtcaacgccatccggaggctggaggaggcccagaagcagcgccaggagcggctggtggcc
ggccagctgcaagtccagcagcagctagaagaggaagagcccaaggtggcctcccggctg
gcccaggagtgccaggcccagcgggcacggctgccacaagagatccgacagagcctgtgg
ggtgagctgccggtggagcaggcggcggaggaggaggaggaggaggaccttgctgcaggc
gatggtcccagcctgggcactgtcagcgggcacacgctgggcagagccagcaatgggcac
gccctggggggcagagccagtaatgggcatgcccaggggagtggcagtggtgtagactgt
gagaggcaagaagagaacacccagctgtga

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