KEGG   Monodelphis domestica (opossum): 100031660Help
Entry
100031660         CDS       T01031                                 

Gene name
PLCB1
Definition
phospholipase C, beta 1 (phosphoinositide-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:mdo00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:mdo04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:mdo04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:mdo04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:mdo04070]
Cellular Processes; Cell communication; Gap junction [PATH:mdo04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:mdo04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:mdo04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:mdo04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:mdo04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:mdo04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:mdo04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:mdo04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:mdo04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:mdo04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:mdo04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:mdo04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:mdo04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:mdo04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:mdo04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:mdo04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:mdo04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:mdo04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:mdo04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:mdo04720]
Organismal Systems; Nervous system; Long-term depression [PATH:mdo04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:mdo04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:mdo04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:mdo04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:mdo05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:mdo05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:mdo05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:mdo05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:mdo05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
1
AA seq 1218 aa AA seqDB search
MAGAQPGVHALQLKPVSVSDNLKKGIKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
TELLDLSLVKDARCGKHARAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISYLNLV
AFQEEVAKEWTDEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRMFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSRPYL
TVDQMMEFINLKQRDPRLNEILYPPLKQEQVQLLIEKYEPNNSLAKKGQISVDGFMRYLS
GEENGVVPPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPYPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSAKK
KLSEQASNTYSDSSSVFEPSSPGAGEADMESDDDDDDDDDCKKSSMDEGTAGSEAMATEE
MSNLVNYIQPVKFESFETSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYP
KGTRVDSSNYMPQVFWNAGCQMVALNFQTVDLAMQLNLGMYEYNGKSGYRLKPEFMRRPD
KHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEIDMFGLPVDTRRKALKTKTSQ
GNAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEGGKFIGHRILPVQAIRPGYHYICLRNE
RNQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVK
KEADLGETPTESKSEPRPAPAENGVNHTASLAPKPPSQVVHSQPAPGSVKAPAKTEDLIQ
SVLTDVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDY
LRRRAVLEKNAKRDSKKKSEPSSPDHVSSTMEQDLAALDAEMTQKLVELKDKQQQQLLNL
RQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEK
ITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEDAQSKRQEKLLEKHKEIRQQILDEK
PKMQVELDQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSSVSSSITSYSSKANHKSPP
NEEELEEDNAERVFDTPL
NT seq 3657 nt NT seq  +upstreamnt  +downstreamnt
atggccggggcacagccaggagttcacgctttgcaactcaaacctgtcagcgtctccgac
aacctgaagaaaggcatcaaatttgtcaaatgggatgatgactctactattgttactccc
attattctgaggacagatccacaaggatttttcttttattggacagatcagaataaggag
actgaactcttagatctcagccttgtcaaggatgccagatgtgggaaacatgccagagcc
ccaaaggacccaaaattacgtgagcttttggatgtgggaaacataggacgcctggaacaa
cgaatgataactgtggtatatggtccagatttggtcaacatttcctatttgaacttagta
gcatttcaagaagaagtagccaaggaatggacagatgaggttttcagtttggcaacaaac
ctgctggcacaaaacatgtctagggacgcatttctggaaaaagcctataccaaactcaag
cttcaagttactcctgaaggaagaattcctctcaaaaacatctatcgcatgttttcagca
gatcgaaaacgtgttgaaactgctttagaagcttgtagtcttccatcttcaaggaatgat
tcaataccacaagaggacttcactccagaagtatacagagttttcttaaacaatctttgt
cctcgacctgaaatcgataacatcttttctgaattcggtgccaagagtagaccatatctt
actgttgatcaaatgatggagtttatcaatttaaagcaacgcgatccccgactcaatgaa
atcctttatccacccttaaaacaggaacaagtccaactactgattgagaagtatgaacct
aacaattccttagcaaaaaaaggacagatctcagtggatggattcatgcgctatctgagt
ggagaagaaaatggagtcgttccgcccgagaaactggatttgaatgaagatatgtctcag
ccactctctcactatttcatcaattcttcacacaacacctacctcacagctggccagtta
gctggcaactcctcagtagagatgtatcgccaagtactcttgtctggctgtcgctgtgtg
gagctggactgctggaagggaaggacagcagaagaagagcctgtcattactcatggtttc
accatgacaacagagatctcttttaaggaggtgatagaagctattgctgaatgtgcattt
aagacatcaccatacccgatcctcctttcttttgaaaaccatgtggattctccaaaacag
caagccaagatggcagaatattgcagactaatatttggagatgcacttcttatggagcca
ttagaaaaatacccacttgaatctggagttcctcttccaagccctatggacttaatgtat
aaaattttggtaaaaaataaaaagaaatcacacaagtcttcagaaggaagtgccaaaaag
aagctttcagaacaggcatccaatacttacagtgactcatccagtgtgtttgaaccttca
tctcctggagcaggagaagcagatatggagagtgatgatgatgatgatgatgacgatgac
tgtaaaaagtcttccatggatgagggaactgctggtagtgaagccatggccacagaagaa
atgtctaacctggtaaactatatacagccagtgaaatttgagtcttttgagacatcaaaa
aaaagaaacaaaagttttgaaatgtcctcttttgtggaaaccaaaggacttgaacaacta
acaaagtctccagtagaatttgtagaatataacaaaatgcagcttagcaggatttatcca
aagggaacacgtgtggattcttcaaattatatgccccaagtcttctggaatgctggctgt
caaatggtagctcttaactttcaaacagtagacttggctatgcaattgaacttgggaatg
tatgaatacaatgggaaaagtggttacagattaaagccagaatttatgagacgaccagac
aaacattttgatccatttactgaaggtatcgtggatggtatagtagccaatactttatct
gttaagatcatttcaggtcaatttctttctgataaaaaagttggcacttatgtggaaata
gatatgtttggcttaccagtggataccaggagaaaagccttgaaaaccaagacttctcag
gggaatgccgtgaatccagtctgggaagaagaacctatagtgtttaagaaggttgtcctg
ccttctctggcatgtctaaggatagcagcatatgaagaaggaggtaaatttattggtcat
cggatattgcctgtacaagcaatacgaccaggttatcactacatttgtctgaggaatgaa
aggaatcagcctctgatgctcccagcagtctttgtatacatagaggttaaagactatgta
ccagatacatatgcggatgtaattgaagcattatcaaatcccatcagatatgtgaatctg
atggaacaaagggctaaacagctggcagcactgaccctagaagatgaagaagaagtaaag
aaagaggccgatcttggggaaacaccaacagagtcgaagagtgaacccagaccggcacca
gcagagaacggggtcaatcacactgcatcactggcaccaaaaccaccatctcaggttgtc
cacagtcaaccagccccaggttcagtaaaagcacctgcaaaaactgaagatcttattcag
agtgtcttaacagatgtggaagcacagacaattgaggaattaaaacaacagaagtctttt
gtgaaacttcagaagaagcattacaaagaaatgaaggaccttgtgaagagacaccacaag
aaaaccactgatctgatcaaagagcacaccacaaagtacaatgaaatccaaaatgattac
ttgcgaaggagggctgtgctagaaaaaaatgcaaaaagagacagtaagaaaaaatctgaa
cccagcagtcctgatcatgtttcttcaacaatggagcaggatcttgctgccctggatgca
gaaatgacacaaaaactggtagaattaaaggacaagcaacagcagcagctactgaatctg
cgacaagaacagtattatagtgaaaaatatcagaagcgagagcatatcaaattgcttatt
cagaagttgacagatgttgcagaagaatgtcagaacaatcaattaaagaaactgaaagaa
atttgtgagaaagaaaagaaagagttgaagaagaaaatggataaaaaaagacaggagaag
ataacagaagcaaagtcaaaagacaagagtcaaatggaagaagagaagactgaaatgatc
cggtcatacatccaagaagtggtgcagtacataaagagactagaagatgcacaaagcaaa
agacaggagaaacttttagagaaacacaaggaaattcgtcaacagatactggatgaaaaa
ccaaagatgcaggtagaacttgatcaggaatatcaagacaaattcaaaaggctccccctg
gaaattctggaatttgtacaagaagccatgaaaggaaaaatcagtgaagatagcaatcac
agttcagtctcttcctccatcacctcatatagcagcaaagcaaaccacaaatctcccccg
aatgaggaagaactagaagaagacaatgcagaaagagtatttgatacacccctttga

DBGET integrated database retrieval system