KEGG   Monodelphis domestica (opossum): 100031869Help
Entry
100031869         CDS       T01031                                 

Gene name
PLCB2
Definition
phospholipase C, beta 2
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Pathways in cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mdo00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100031869 (PLCB2)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100031869 (PLCB2)
   04310 Wnt signaling pathway
    100031869 (PLCB2)
   04020 Calcium signaling pathway
    100031869 (PLCB2)
   04070 Phosphatidylinositol signaling system
    100031869 (PLCB2)
   04022 cGMP - PKG signaling pathway
    100031869 (PLCB2)
 Cellular Processes
  Cellular commiunity
   04540 Gap junction
    100031869 (PLCB2)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100031869 (PLCB2)
   04062 Chemokine signaling pathway
    100031869 (PLCB2)
  Endocrine system
   04911 Insulin secretion
    100031869 (PLCB2)
   04912 GnRH signaling pathway
    100031869 (PLCB2)
   04915 Estrogen signaling pathway
    100031869 (PLCB2)
   04921 Oxytocin signaling pathway
    100031869 (PLCB2)
   04918 Thyroid hormone synthesis
    100031869 (PLCB2)
   04919 Thyroid hormone signaling pathway
    100031869 (PLCB2)
   04916 Melanogenesis
    100031869 (PLCB2)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100031869 (PLCB2)
   04270 Vascular smooth muscle contraction
    100031869 (PLCB2)
  Digestive system
   04970 Salivary secretion
    100031869 (PLCB2)
   04971 Gastric acid secretion
    100031869 (PLCB2)
   04972 Pancreatic secretion
    100031869 (PLCB2)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100031869 (PLCB2)
  Nervous system
   04724 Glutamatergic synapse
    100031869 (PLCB2)
   04725 Cholinergic synapse
    100031869 (PLCB2)
   04728 Dopaminergic synapse
    100031869 (PLCB2)
   04726 Serotonergic synapse
    100031869 (PLCB2)
   04720 Long-term potentiation
    100031869 (PLCB2)
   04730 Long-term depression
    100031869 (PLCB2)
   04723 Retrograde endocannabinoid signaling
    100031869 (PLCB2)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100031869 (PLCB2)
  Environmental adaptation
   04713 Circadian entrainment
    100031869 (PLCB2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100031869 (PLCB2)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100031869 (PLCB2)
   05016 Huntington's disease
    100031869 (PLCB2)
  Infectious diseases
   05146 Amoebiasis
    100031869 (PLCB2)
   05142 Chagas disease (American trypanosomiasis)
    100031869 (PLCB2)
   05143 African trypanosomiasis
    100031869 (PLCB2)
Enzymes [BR:mdo01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100031869 (PLCB2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
1
AA seq 1188 aa AA seqDB search
MSLLNPVLLPPELKSYLTRGERFIKWDDETSVASPVILRVDPKGYYLYWTYQSKEMEFLD
ITSIRDTRFGKFAKMPKTQKLREVFNLDFPDNTFLLKTLTVVSGPDMVDLTFHNFVSYKE
NVGKDWAEDVLALAKNPWAANAPRSTFLEKILVKLKMQLSPEGKIPVKNFFQMFPADRKR
VEAALSACHLPKGKNDSINPEDFPEPVYRSFLMSLCPRPEIDEIFTSHHAKAKPYMTKEH
LTKFINQKQRDARLNSLLFPPARPDQVQCLIEKYEPSGINIQRGQLSPEGMVWFLCGPEN
SIVAQDKLMLHQDMSQPLNHYFINSSHNTYLTAGQFSGPSSSEMYRQVLLSGCRCVELDC
WKGKPPEEEPIITHGFTMTTDILFKDAVEAIAESAFKTSLYPVILSFENHVDSPRQQAKM
AEYCRTIFGDMLLTEPLDKFPLKSGVPLPSPQDLLGKILIKNKKNQSSAPVPPKKELCTE
TEGSQANAAMGEDTVWVGEEEAELEEEEEEEEEEEESGSLDEEEIKKMQSDEGTAGLEVT
AYEEMSSLVNYIQPTKFISFEFSSQKNRSYVISSFTELKAYDLLTKSPVQFVDYNKRQMS
RIYPKGTRMDSSNYSPQMFWNAGCQMVALNFQTMDMPMQQNMALFEFNGQSGYLLKHEFM
RRPDKHFDPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVEVFGLPGDPKRRYRTK
LTPSANSINPVWKEDPFVFEKIMMPELASLRVAVLEEGGKFIGHRIIPVHALHSGYHHLC
LRSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKFFNAQDKKSVKLKETENSAP
EKPLTPRNSAVGQLNGALASAGSSTAPPSNGPAVAVTWLKEEALKEAAEPQTASLEELQQ
LKGFLKLQKRQEKELRELERQGARRWEEVLQKYANLQTELTPQGGCRKLSITKGSRKKRS
LPCEETGGAGMGPIEGPESSDGRIRELKEKLEMELYQQGEEQYESIMKRKEAHGSELMDK
VLKLAQEKQAAELKALKESADGNTKEMKKKLEVKRLERIQAMSKITSDKMAQERLKREIN
NSHIQEVVHIIKQMTETLERHQERLEEKQAACLEQIREKGKQFQQEALSEYEERMKGLEA
KVKEAVKCCLSFPQDVHNKKPETPGAVEEPLEETLSPAEASSQLDSRL
NT seq 3567 nt NT seq  +upstreamnt  +downstreamnt
atgtctctgctgaaccccgtcctgctgccccctgagctgaagagctacctgacccgagga
gagcgcttcatcaagtgggatgatgagacttcagtggcctccccggtcatccttcgagtg
gatcctaagggatattatttgtactggacctatcaaagcaaggagatggagttcctggac
atcaccagcatccgggacactcggtttggcaagtttgctaagatgcccaagacccagaaa
cttcgagaagttttcaacttggacttccctgacaacaccttcttgctgaagaccctgact
gtggtgtctggcccagacatggtggacctgaccttccataactttgtctcctacaaagag
aatgtcggcaaggactgggctgaagacgttctggctttggctaagaacccatgggcagcc
aatgctccccggagcacattcctggagaagatcctggtaaagcttaagatgcagctcagt
cctgaagggaagatccccgtgaagaatttttttcagatgtttcctgctgaccggaaacga
gtagaggctgcactcagtgcctgtcaccttcccaagggcaaaaatgactccatcaacccg
gaggatttccctgagcctgtctacaggagcttcctcatgagtctgtgtccccgacctgag
atcgatgagattttcacctctcatcatgccaaagcaaagccttacatgaccaaggagcat
ctgaccaagttcattaaccaaaagcagcgggatgcccgactcaactccctactcttccca
ccggcccgacctgaccaagtacagtgcctcattgaaaagtatgaacccagtggcatcaac
atccagaggggtcagctgtccccagaggggatggtttggttcctatgtggtccagagaac
agtatagtggcccaagacaaactgatgctgcatcaggacatgagccagcctctgaatcac
tacttcatcaactcctcccacaacacctacctgacagctggccagttctcggggccctcg
tcctcagagatgtacagacaggtcttgctctctggatgtcgctgtgtggagcttgactgc
tggaaggggaagcctcctgaagaagagcccatcatcactcatggtttcaccatgaccaca
gacattttattcaaggatgcggtagaggccattgctgagagtgccttcaagacctccctc
tacccggtcatcttgtcctttgagaaccatgtagactcgcctcgacagcaagctaagatg
gcagagtactgtagaaccatatttggggacatgctgctcactgagcccctggacaagttc
cctttgaagtcaggggtccccctccccagtccccaggaccttctgggcaagatccttatc
aagaataagaagaatcagtcctccgctcctgttccacccaagaaagaactgtgtacggaa
acagagggtagccaggccaatgcagccatgggtgaggacacagtgtgggttggtgaagaa
gaggctgagctggaggaagaggaggaagaagaagaagaagaggaagaatcaggtagtttg
gatgaagaggaaatcaagaagatgcagtcggatgagggcacagctggcctggaggtgaca
gcatacgaggagatgtctagcctggtcaactacatccagcccaccaagttcatctccttc
gagttctcctcccagaagaatcggagttatgtcatctcttcctttacggagctgaaggcc
tatgatctgctcaccaagtcccctgtgcagtttgtggactataacaagaggcaaatgagt
cggatctaccccaagggcacacgaatggactcatctaactactctccccagatgttctgg
aatgcaggctgccaaatggtggccctcaatttccagacaatggatatgcccatgcagcag
aacatggcactgtttgagttcaacgggcagagtggctaccttctcaagcacgagttcatg
cgccggccggacaagcattttgacccgttctccgtggaccgcatcgatgtggtggtggcc
accactctctccatcacggtgatttctggccagtttctgtcggaacgaagtgtccgaact
tacgtggaggtggaggtgtttggcttgcctggagaccccaagaggcgctaccgcaccaaa
ctgacacccagcgccaactccataaatcccgtctggaaagaggacccctttgtctttgag
aagatcatgatgccagaactagcctctctgagagtggcagtcctggaagaaggaggcaag
tttatcgggcaccgaattatcccagtccatgccctgcactcagggtaccatcacttgtgc
ctcaggagtgagagcaacatgcccctcaccatgcctgccctcttcgttttcctggagatg
aaagattatgtgcctgacacatgggcagatctcactgtggctcttgccaaccccatcaaa
ttcttcaatgctcaagacaagaagtcagtcaagctgaaggaaacagagaacagcgcccct
gagaagcctttgacgcccaggaactcggctgtgggccagctcaacggggccctggcgtcc
gccggctcctccacggcgccgccgtccaacggtcctgcagtggctgtgacctggctgaag
gaggaagcattgaaagaggcagcagaacctcagacagccagtctggaggagctgcagcag
ttgaaagggttcctgaagcttcagaagagacaggaaaaggaacttcgggaactggagagg
caaggtgcccgtcgctgggaagaagttctgcaaaagtatgccaacttacagactgaattg
acaccccagggtgggtgcaggaagctgtccatcactaagggatccaggaagaagagaagc
ttgccttgtgaggagactggcggggccgggatgggaccaatcgaaggaccagaaagctca
gatgggcgcattcgagagctgaaggagaagctggagatggaactgtaccaacaaggggag
gagcagtatgaaagcatcatgaaacgcaaggaagctcatggtagtgagctaatggacaag
gtgctaaagctggcccaggaaaaacaagcagccgaactaaaggctctcaaggagtctgca
gacggcaataccaaagagatgaaaaagaagcttgaagtcaagaggctagagcggatccag
gccatgagcaagatcactagtgacaagatggcccaggagaggctgaagagagaaattaac
aactcacatatacaggaagtggtccatatcatcaaacagatgacagagactctggagagg
caccaggagaggctggaagaaaagcaggcggcttgtctggagcagatccgggagaaaggg
aagcagttccagcaagaggcattgtctgaatatgaggaacgcatgaagggcctggaagcc
aaagtgaaggaggcggtgaagtgctgtctcagtttcccccaagatgtccacaacaagaag
ccagagacacctggtgctgtggaagaacctttggaggagacattgagcccagctgaggct
tcttcccagctagacagccgtctctaa

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