KEGG   Monodelphis domestica (opossum): 100032696Help
Entry
100032696         CDS       T01031                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mdo00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100032696 (PLCG1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100032696 (PLCG1)
   04015 Rap1 signaling pathway
    100032696 (PLCG1)
   04012 ErbB signaling pathway
    100032696 (PLCG1)
   04370 VEGF signaling pathway
    100032696 (PLCG1)
   04064 NF-kappa B signaling pathway
    100032696 (PLCG1)
   04066 HIF-1 signaling pathway
    100032696 (PLCG1)
   04020 Calcium signaling pathway
    100032696 (PLCG1)
   04070 Phosphatidylinositol signaling system
    100032696 (PLCG1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100032696 (PLCG1)
   04660 T cell receptor signaling pathway
    100032696 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    100032696 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    100032696 (PLCG1)
   04670 Leukocyte transendothelial migration
    100032696 (PLCG1)
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100032696 (PLCG1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100032696 (PLCG1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100032696 (PLCG1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100032696 (PLCG1)
   05206 MicroRNAs in cancer
    100032696 (PLCG1)
   05205 Proteoglycans in cancer
    100032696 (PLCG1)
   05214 Glioma
    100032696 (PLCG1)
   05223 Non-small cell lung cancer
    100032696 (PLCG1)
  Infectious diseases
   05169 Epstein-Barr virus infection
    100032696 (PLCG1)
Enzymes [BR:mdo01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100032696 (PLCG1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
1
AA seq 1292 aa AA seqDB search
MMAGAGAPFANGCGSCAPSEAEVLNLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQ
ITWSRGADKIEGAVDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKT
LSLQATSEDEVNMWIKGLNWLVTDTTQSATPLQIERWLRKQFYSVDRNREDRISAKDLKN
MLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMFSAQKTMDLPFLEAGTLR
GGDRPELCRVSLAEFQQFLLEYQGELWATDRLQVQEFMLNFLRDPLREIEEPYFFLDEFV
TFLFSKENNIWNSQLDLVCVDTMNNPLSQYWISSSHNTYLTGDQFSSESSLEAYARCLRM
GCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVTSEYPVILSIEDHCSI
AQQRNMAQYFKKVFGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSV
MYSENDISNSIKNGILYLEDPINHEWYPHYFVLTSSKIYYSEETNSDQGNDDEEEPKEVN
SSAELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSF
WRNGKVQHCRIHSRQDAGSPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLTEPVPQ
TNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRSEPNSYAISFRAEGKIKHCRVQQ
EGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRN
PGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQL
WFPSNYVEEMASPAALEPEREQLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSI
SMASIAHWSLDVAADSQEDLQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVIY
CRPVPFDEDKIGTERACYRDMSSFPETKAEKYVNKTKGKKFLQYNRLQLSRIYPKGQRLD
SSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMSSGRCGYVMQPSNMRDEAFDPFDK
CSLRGIEPCAVCIEVLGARHLPKNGRGIVCPFVEIEVAGADYDNMKHKTEFVVDNGLNPV
WPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFLVKGLKTGYRAVPLKNNYSED
LELASLLIKIDIFPAKQENGEVSPFGSSSFRERGSEAPGQLLHGRTREGSFEARYQQPFE
DFRISQEHLADHFDGRERRALRRTRVNGDNRL
NT seq 3879 nt NT seq  +upstreamnt  +downstreamnt
atgatggcaggggcgggagcccctttcgccaatggctgcgggtcctgcgccccatccgag
gccgaggttctgaatctctgccggagtttggaagtgggcaccgtcatgaccttgttctac
tccaagaaatcccagcgaccggagaggaaaaccttccaggtcaagttggagaccaggcag
atcacgtggagccgtggggcagataaaatcgaaggagccgttgatattcgtgaaatcaag
gagattcgcccaggaaagacctctcgtgactttgaccgttatcaggaagacccggctttc
cggcctgaccagtcccattgctttgtcatcctgtatggcatggaattccgcctgaaaacc
cttagtctgcaagccacctcggaggacgaagtgaacatgtggatcaaaggcttgaattgg
cttgtgactgacaccacccagtctgccactcctctgcagattgagaggtggcttcggaag
cagttctactcagtagatcggaatcgggaagacaggatttctgccaaggatcttaagaac
atgctgtcccaggtcaactaccgagttcccaacatgcggttcctgagggaacggttgacg
gatctggagcagcggagtggggacatcacctatggacagtttgcacagctctaccggagc
ctcatgttcagcgcccagaaaacgatggaccttcctttcctggaagctggcaccctgagg
ggtggagatcgacctgagctctgcagagtgtccctggctgagtttcagcagtttcttttg
gaataccagggggagctgtgggccactgaccggctccaggtgcaggagttcatgctcaac
ttcctccgagatccactccgagagatagaggagccttacttcttcctggatgagtttgtt
accttcctgttctccaaagagaacaacatctggaactcccagctggatttggtgtgtgtc
gacaccatgaataatcccttgtctcagtattggatctcttcatcccataacacgtacctg
actggggaccagttctccagcgagtcctccttggaggcctacgcacggtgtcttcgcatg
ggctgtcgatgcattgagttggactgttgggatgggccagatgggatgcctgtcatttac
cacggacataccctcaccaccaagatcaagttctctgacgttctccataccatcaaggag
catgcgttcgtgacctcagagtacccagtgatcttgtccattgaagatcattgtagcatt
gctcagcagagaaacatggcccagtacttcaagaaagtatttggtgacacccttcttacc
aagcctgtggacatcgccgctgatggtctgccttcccccaaccagctcaagagaaaaatc
cttattaagcacaagaagctggccgagggcagtgcctacgaggaggtgcccacatcagtg
atgtactcggagaatgacatcagcaattccatcaagaatggcatcctctacttggaagat
cccattaaccatgagtggtacccgcactactttgtactgaccagcagcaaaatctactac
tcagaggagacaaatagtgaccagggcaacgatgatgaggaggaaccaaaggaggtgaat
agcagtgcagagctacactccagtgagaaatggttccatggcaagctaggcgctggtcgt
gatgggcggcacattgctgagcgactgctcactgaatactgcattgagacgggagcccct
gatggctcctttctggttcgagagagcgagacctttgtcggggactacacactctccttc
tggcggaatgggaaggtccagcattgccggatccactcacgccaggatgccgggagcccc
aaattctttttgacagacaacctggtatttgactcgctctacgacctcatcacccactac
cagcaggtgccattgagatgcaatgagttcgagatgcgccttacggagcctgtgcctcag
accaatgcccacgagagcaaagagtggtaccatgcaagtctgacccgcgcccaggcggag
cacatgttaatgcgtgtaccccgggatggagccttccttgtgcgaaaacggagtgagccc
aactcctatgccatctccttccgggctgaaggcaagatcaaacactgccgcgtccagcag
gaggggcagactgtgatgctggggaactctgagtttgacagcctcgtggacctcatcagt
tactatgagaagcatccgctgtaccgaaagatgaagctccggtaccccatcaatgaggag
gcactagagaagattggcacagcggagccagactatggagctctctatgaaggacggaac
ccaggtttctatgtggaagcaaatcctatgccaacttttaagtgtgcagtcaaagccctc
tttgactacaaggcacagagagaagatgagctgacctttacgaagagtgccatcattcag
aatgtagaaaagcaggagggaggctggtggaggggagactacggagggaagaagcagcta
tggtttccatcaaattatgtggaagagatggccagccccgctgctctagagcctgagagg
gagcagctggatgagaatagccccctgggagatctgctccgtggagtcctggatgtgcca
gcctgtcagattgctatccgcccagaggggaagaacaaccgcctgttcgtattctccatt
agcatggcctccattgcacattggtccctggatgtggctgctgattcccaggaggaccta
caggactgggtgaaaaagatccgggaggtggcccagaccgcagatgcccggctcacagag
gggaagatgatggaacgaaggaagaaaatcgccttggagctgtctgaactcgtcatctac
tgtcggcccgtccccttcgatgaggacaagatcggcaccgagcgggcctgttaccgagac
atgtcgtccttcccggagaccaaggcggagaagtacgtgaataagaccaagggcaagaag
ttcttacagtataatcggcttcagctgtcccgcatctaccccaagggccagcggctggac
tcctctaactatgaccccctgcccatgtggatctgtggcagtcagctcgtggccctcaac
ttccagacgccagacaaacccatgcagatgaaccaggccttgttcatgtccagtgggcgc
tgtggctatgtgatgcagccaagcaacatgagagatgaagcctttgacccctttgacaag
tgcagcttgcgggggatagagccatgtgcagtctgcattgaggtcctgggggcccggcat
ctccccaagaacggtcgtggcatcgtgtgccctttcgtggagattgaggtagcgggggcc
gactacgacaacatgaagcacaagaccgaatttgtggtggacaatggcctgaaccccgtg
tggccggcaaagcccttccacttccagattagcaaccctgagtttgctttcctgcgcttt
gtggtgtatgaagaagacatgttcagcgaccagaatttcttggctcaggctaccttcctt
gtgaaaggcctaaagacaggatacagagcggtgcctttgaagaacaactacagcgaggat
ctggagctggcctcgctgcttatcaaaatagatatatttcctgccaagcaggagaacggt
gaagtcagtccctttggcagctcctcattccgagaacggggctccgaagctccgggccag
ctactccacggacggacccgagagggctcctttgaagcccgctatcagcagccatttgag
gatttccgcatctcccaggagcacctagcagaccactttgacggccgggaacgaagggcc
cttcggagaactcgtgtcaacggagacaaccgcctctag

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