KEGG   Monodelphis domestica (opossum): 100033281Help
Entry
100033281         CDS       T01031                                 

Gene name
PLCB4
Definition
phospholipase C, beta 4
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mdo  Monodelphis domestica (opossum)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mdo00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100033281 (PLCB4)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100033281 (PLCB4)
   04310 Wnt signaling pathway
    100033281 (PLCB4)
   04020 Calcium signaling pathway
    100033281 (PLCB4)
   04070 Phosphatidylinositol signaling system
    100033281 (PLCB4)
   04022 cGMP - PKG signaling pathway
    100033281 (PLCB4)
 Cellular Processes
  Cell communication
   04540 Gap junction
    100033281 (PLCB4)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100033281 (PLCB4)
   04062 Chemokine signaling pathway
    100033281 (PLCB4)
  Endocrine system
   04911 Insulin secretion
    100033281 (PLCB4)
   04912 GnRH signaling pathway
    100033281 (PLCB4)
   04915 Estrogen signaling pathway
    100033281 (PLCB4)
   04921 Oxytocin signaling pathway
    100033281 (PLCB4)
   04918 Thyroid hormone synthesis
    100033281 (PLCB4)
   04919 Thyroid hormone signaling pathway
    100033281 (PLCB4)
   04916 Melanogenesis
    100033281 (PLCB4)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100033281 (PLCB4)
   04270 Vascular smooth muscle contraction
    100033281 (PLCB4)
  Digestive system
   04970 Salivary secretion
    100033281 (PLCB4)
   04971 Gastric acid secretion
    100033281 (PLCB4)
   04972 Pancreatic secretion
    100033281 (PLCB4)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100033281 (PLCB4)
  Nervous system
   04724 Glutamatergic synapse
    100033281 (PLCB4)
   04725 Cholinergic synapse
    100033281 (PLCB4)
   04728 Dopaminergic synapse
    100033281 (PLCB4)
   04726 Serotonergic synapse
    100033281 (PLCB4)
   04720 Long-term potentiation
    100033281 (PLCB4)
   04730 Long-term depression
    100033281 (PLCB4)
   04723 Retrograde endocannabinoid signaling
    100033281 (PLCB4)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100033281 (PLCB4)
  Environmental adaptation
   04713 Circadian entrainment
    100033281 (PLCB4)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100033281 (PLCB4)
   05016 Huntington's disease
    100033281 (PLCB4)
  Infectious diseases
   05146 Amoebiasis
    100033281 (PLCB4)
   05142 Chagas disease (American trypanosomiasis)
    100033281 (PLCB4)
   05143 African trypanosomiasis
    100033281 (PLCB4)
Enzymes [BR:mdo01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100033281 (PLCB4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
1
AA seq 1175 aa AA seqDB search
MAKPYEFNWQKPVSPFIQEGAIFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVL
ECSLINSIRFGSVPKDPKILAALEAFGKSESDLEGRIVCVCSGTDLVNISFTYMVAENPE
VAKQWVEGLRAIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFRKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDDELKTKGLISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQILLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQALESHPLEPGRSLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSM
MEAGESAAPVNILEDDNEEEIESADQEEEAHPEFKFGSELSADDFSQKEAVANSVKKGLV
TVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFNVAEERNIHYNMSSFNESVG
LGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQL
NQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGT
YVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNK
LIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGFGDIVDALSDPKK
FLSVMEKRADQMRAMGIETSDIADVPNDTSKNDKKGKANNAKASVTPQSSSELRPATTSA
LGAGIEGKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQ
VDKIVAQYDKEKLSHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQH
TKEWSEMINTHSAEEQEIRDLHLSQQCDLLKKLLISAHEQQTQQLKLSHDRECKEMRANQ
AKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQ
LEHLEVLEKQNEQAKEMQQMVKLEAEMDRRPATVV
NT seq 3528 nt NT seq  +upstreamnt  +downstreamnt
atggccaaaccatatgaatttaactggcagaaaccagtctctccatttatacaggaggga
gccatttttgacagatatgaagaggagtcctttgtatttgaacctaactgccttttcaaa
gtggatgaatttggcttctttttgacctggaaaagtgaaggaaaggaaggacaggtatta
gagtgttccctgattaacagcattcgttttggatctgtaccaaaggatcccaaaatacta
gcagctcttgaggcttttggaaaatcagagagtgatctggaggggaggatagtatgtgtc
tgcagtggcaccgacctggtgaatatcagcttcacttatatggtggcagaaaatccagaa
gttgctaagcaatgggtagaagggttaagagccatcatacataattttagagctaacaat
gttagtccaatgacatgcctcaagaaacactggatgaaattggcatttatgacaaacaca
aatggtaaaattccagttaggagtattactagaacttttgcatcaggtaaaacagaaaag
gtgatttttcaagcacttaaggagctaggtcttcccagcggaaagaatgatgaaatcgag
cctgcagcatttacttatgaaaaattttatgaactaacacaaaaaatttgtcctcggact
gacatagaggacctctttaggaaaatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagaccctcgactgaatgaaattttattc
ccattctatgatacaaaaagggcaatgcagataattgagacttatgagcctgatgatgag
ttgaagacaaaagggctcatatccagtgatgggttttgcagatatctgatgtcagatgaa
aatgctccagtcttcctagaccgcctggaactttaccaagaaatggatcatcctttggca
cactatttcatcagttcttcccataacacatatctcacaggacgtcagtttggtgggaaa
tcttctgtggaaatgtacagacaaatactcttagctggatgcagatgtgttgagctagat
tgctgggatggtaaaggagaagatcaagaaccaattataactcacggaaaagcaatgtgt
acagatattctctttaaggatgtgattcaagccatcaaggaaacagcctttgttacatca
gagtatcctgtcattctgtcctttgaaaaccactgcagcaaatatcaacagtacaagatg
tccaagtattgtgaagatctatttggggatctcctgttgaaacaagcacttgaatcacat
ccacttgaaccaggaagatcattaccatcccctaatgacctcaaaagaaaaatactcatc
aaaaacaagagactgaaacctgaggtggaaaaaaaacagcttgaagcattaaaaagtatg
atggaagcaggagagtcagcagccccagtaaatatcttggaagatgacaacgaggaagaa
atagaaagtgctgaccaagaggaggaagctcacccagaattcaaatttggaagtgaactc
tctgctgatgacttcagtcaaaaggaagctgttgcaaatagtgtaaagaagggattagtt
actgtggaagatgagcaggcatggatggcttcctataaatacgtgggcgctacaaccaat
attcacccatatttatccacaatgatcaactatgcccagcctgtaaagtttcagggcttc
aatgtagcagaagaacgcaatattcattacaatatgtcttcttttaatgaatcagttgga
ctaggttatttgaagacacatgcaattgaatttgtgaattataataaacgacaaatgagt
cggatttaccccaagggaggccgagtggattccagtaattacatgcctcagattttctgg
aacgctggctgccagatggtctcactgaactatcaaaccccagatttagcgatgcaattg
aatcagggaaaatttgaatataacggatcatgcgggtaccttctcaaaccagatttcatg
agacggccagatcgaacatttgatcctttctctgaaacacctgtagatggtgttatagca
gccacttgttcagtgcaggtcatatcagggcaattcttatctgataagaaaattggtacg
tatgtagaagtggatatgtatggtttgcccacagacactatccgtaaggagttccgaact
cgtatggttatgaacaatggtctcaatccggtttacaatgaggaatcgttcgtattccga
aaggttatcctccctgatctggctgtcttgagaatagctgtgtatgatgacaacaacaag
ctgattggtcaaagaatcctcccacttgatggcctccaggcaggctacagacacatttct
cttcgaaatgaagggaataaaccattatcactgccaactgttttctgcaacattgtgctt
aaaacatatgtgcccgatggttttggagatattgtggatgctttgtcagacccaaagaaa
tttctttctgtaatggaaaagagagcagatcagatgagagccatgggtattgaaactagt
gacatagctgatgtgccaaatgacacttccaagaatgacaagaaaggaaaagccaataat
gctaaggctagtgtgactcctcagagcagttctgaactcagaccagccaccacctccgcc
ttgggagcaggaattgaagggaagaaaggtattgaacttatccctcaagtgaggatagaa
gatttaaaacaaatgaaggcttacttgaaacacttaaagaaacaacagaaagaattaaat
tctttaaagaagaagcatgcaaaggaacacagcaccatgcagaagctacactgcacacaa
gttgacaaaatcgtggcacaatatgacaaggagaagttatctcatgagaaaattttagag
aaagcaatgaagaagaagggaggaagtaattgtcttgaaatgaagaaagaaactgaaatt
aaaattcagacattaacatcagatcataaatctaaggtaaaagagattgtagctcagcat
acaaaagagtggtcagaaatgattaatacccacagtgctgaggagcaagaaatccgggat
cttcacctcagccagcaatgcgatcttctgaaaaagctgctgatcagtgctcacgagcag
caaactcagcagctgaagctctcccacgacagagaatgcaaggaaatgcgtgccaatcag
gccaagatttcgatggaaaacagcaaagccatcagccaagacaaatctatcaaaaataaa
gcagaaagagagaggagagtcagagaactaaacagcagtaacactaaaaagtttctggaa
gaaagaaagagactcgcaatgaaacagtctaaagaaatggatcagttgaaaaaagttcaa
cttgaacatctagaagtcctggaaaaacagaatgagcaggcaaaggagatgcagcagatg
gtgaaattggaagccgagatggaccgaagaccagcaacagtggtgtaa

DBGET integrated database retrieval system