PMID:
     1570292
Authors:
     Anderson JA, Huprikar SS, Kochian LV, Lucas WJ, Gaber RF.
Title:
     Functional expression of a probable Arabidopsis thaliana potassium channel in
     Saccharomyces cerevisiae.
Journal:
     Proc Natl Acad Sci U S A. 1992 May 1;89(9):3736-40.
Abstract:
     We report the isolation of a cDNA (KAT1) from Arabidopsis thaliana that encodes a
     probable K+ channel. KAT1 was cloned by its ability to suppress a K+
     transport-defective phenotype in mutant Saccharomyces cerevisiae cells. This
     suppression is sensitive to known K+ channel blockers, including
     tetraethylammonium and Ba2+ ions. The KAT1 cDNA contains an open reading frame
     capable of encoding a 78-kDa protein that shares structural features found in the
     Shaker superfamily of K+ channels. These include a cluster of six putative
     membrane-spanning helices (S1-S6) at the amino terminus of the protein, a
     presumed voltage-sensing region containing Arg/Lys-Xaa-Xaa-Arg/Lys repeats within
     S4, and the highly conserved pore-forming region (known as H5 or SS1-SS2). Our
     results suggest that the structural motif for K+ channels has been conserved
     between plants and animals.

This page is constructed based on the NCBI service.