KEGG   Mannheimia haemolytica 89010807N: WC39_09480
Entry
WC39_09480        CDS       T03749                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
mhaq  Mannheimia haemolytica 89010807N
Pathway
mhaq00290  Valine, leucine and isoleucine biosynthesis
mhaq00620  Pyruvate metabolism
mhaq01100  Metabolic pathways
mhaq01110  Biosynthesis of secondary metabolites
mhaq01210  2-Oxocarboxylic acid metabolism
mhaq01230  Biosynthesis of amino acids
Module
mhaq_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mhaq00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    WC39_09480
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    WC39_09480
Enzymes [BR:mhaq01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     WC39_09480
SSDB
Motif
Pfam: HMGL-like LeuA_dimer NAD_binding_10
Other DBs
NCBI-ProteinID: AKA11881
UniProt: A0A249A2I2
Position
complement(1855460..1857004)
AA seq 514 aa
MSNNNIIIFDTTLRDGEQSLKASLTVKEKLQIALALERLGVDVMEVGFPVSSAGDFESVQ
TIARHIKNSRVAALSRAVAKDIDAAYEALKVAEAFRIHTFIASSALHVEAKLKRSFDDVV
EMAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNE
YGNIIHQVMNRVPNIDKAIVSVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNT
ALEEVVMAIKTRQEFMGVDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGI
HQDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYTETDYDLDKLYEA
FLQLADKKGQVFDYDLEALAFIDMQQGDEDRLKLDVITTQLISGLPASAFVQVELDGVRQ
SATSQGGNGPVEATYNAIMNIVGMELKMSHYNLTAKGEGAEALGQVDIVVEYEGRKFHGV
GLATDIVESSARALIHAINAIYRSQKVADLKAKK
NT seq 1545 nt   +upstreamnt  +downstreamnt
atgagcaacaataacattattatttttgatacgactttacgtgatggtgagcaatcatta
aaagcaagtttaaccgtaaaagaaaaattgcaaattgcccttgctttagaacgtttaggg
gttgatgtgatggaagtcggttttccagtttcttcagcgggcgattttgaatcagtacaa
accatcgctcgtcatatcaaaaacagccgggtggcggcgctttcccgagcggttgcaaaa
gacattgatgcagcttatgaagccttaaaagtagcagaagcattccgtatccataccttt
attgccagctcggcattacacgttgaggctaaattaaaacgttcatttgatgatgtagtc
gaaatggcggttgcagcggtaaaacgcgccagaaattatactgatgatgttgagttttcc
tgtgaagatgctgggcgtactggaattgataacatctgccgcattgtagaagctgccatt
aatgccggtgcaaccacagtgaatattccggatacagtcggtttctgtttaccgaatgaa
tacggcaatattatccaccaagtgatgaaccgtgttccgaatatcgataaagcgattgtc
tctgttcactgccataacgatttaggtatggctaccgccaactcattgacagcggtgcaa
aacggagcgagacagattgagtgtactatcaacggtattggcgaacgtgccggtaacacc
gctcttgaagaagtggtaatggcaattaaaacccgccaagaatttatgggggttgatacc
cgcattaatacccaagaaattcaccgtgtcagccaaatggtcagccagctttgcaatatg
ccgattcagccgaacaaagcgattgtcggtagcaatgcctttgctcactcttcaggtatt
caccaagacggtatgctgaaaaataaaaatacttatgaaattatgtcgccggaaaccatc
ggcttgaaaaaagagaagctgaatttaactgcccgttcaggtagagcagcggtgaaaggg
catatggctgatatgggttatacggaaacggattacgatttagataaactttatgaggcc
ttcttgcaacttgctgataaaaaagggcaagtgtttgattatgacttagaagctcttgcc
ttcattgatatgcagcaaggcgatgaagaccgcttaaaattagatgtaattaccacccaa
ctaatcagcggtttaccggcttcggcttttgtacaggtggaattagacggcgttcgtcaa
agtgctacatctcaagggggaaatggtccagttgaggcaacttacaatgccattatgaac
attgtgggaatggagctaaaaatgtcgcactataatctgactgcgaaaggcgaaggagca
gaagcattagggcaagtggatattgtagtggaatatgaaggtcgaaaattccacggtgtg
ggtttggcaaccgatattgtggaatcttcagcccgagctttaattcacgccattaatgcg
atttaccgttcacaaaaagtggcagatttaaaagcgaagaaataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (24)   

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