KEGG   Mycobacterium sp. KMS: Mkms_0691Help
Entry
Mkms_0691         CDS       T00442                                 

Definition
uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase (EC:2.1.1.107 4.2.1.75)
Orthology
K13542  
uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
Organism
mkm  Mycobacterium sp. KMS
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Module
Heme biosynthesis, glutamate => protoheme/siroheme
Brite
KEGG Orthology (KO) [BR:mkm00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    Mkms_0691
Enzymes [BR:mkm01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     Mkms_0691
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.75  uroporphyrinogen-III synthase
     Mkms_0691
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
JGI: 
UniProt: 
Position
743321..744985
Genome map
AA seq 554 aa AA seqDB search
MTRQESGRGRKMKPGRITFVGSGPGDPGLLTARAHSVLVNAALVFTDPDVPEAVLSLVGA
HLPPPSGPEPAEPADAADEQAGSTIPGGPDIRPALGDPAEVAKVLAGEAKHGVDVVRLVA
GDPLSVDAVIAEVNALAKSHANFEIVPGLPNTTAVPTYAGLPLGSTHTVADVRDPNVDWA
ALAAAPGPLILHATASHLPDAARTLIEYGLAETTPAVVTANGTTCQQRSVESTLSGLLDK
AALTAPDATGAPAAPLAGPLVVTLGRTVTNRARLNWWESRALYGWTVLVPRTKDQAGEMS
DKLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFNEF
GLDARAFSGVKIACVGQATAERVRAFGINPELVPTGEQSSLGLLDEFPPYDDIFDPVNRV
LLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPASTREMIKTGGFDAVCFTSSST
VRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAAVGPLVEALAEHAARLRA
EGALPPPRKKSRRR
NT seq 1665 nt NT seq  +upstreamnt  +downstreamnt
atgactcggcaggagagcgggcgtgggcgcaagatgaagcccggccgcatcaccttcgtg
ggctcgggcccgggcgaccccggcctgttgaccgcacgggcccacagtgtgctcgtcaat
gccgcgctggtcttcaccgaccccgacgtccccgaggcggtgctgtccctggtgggcgcg
cacctgcccccaccgtcgggccctgaaccggccgagccggcggacgccgccgacgagcag
gcgggctcgaccatccccggcggcccggacatccggcccgcgctgggcgatccggccgag
gtggccaaggtcctggccggtgaggccaagcacggtgtggacgtggttcggctggtggcc
ggcgacccgctgtcggtcgacgccgtcatcgccgaggtgaacgcgctggccaagagccac
gccaacttcgagatcgtgcccggcctgccgaacaccaccgcggtcccgacgtacgccggc
ctgccgctgggttccacccacaccgtcgccgatgtgcgcgacccgaacgtggactgggcg
gccctggccgccgcgcccggcccgctgatcctgcacgcgaccgcctcgcatctgcccgac
gccgcgcgcacgctgatcgagtacggcctggccgagaccaccccggcggtggtcaccgcc
aacggcaccacctgccagcagcgctcggtcgagtcgacgctgtccgggctgctcgacaag
gccgcgctgaccgcaccggacgcgaccggtgcacccgccgcaccgctggccggcccgctg
gtcgtgacgctcggccgcaccgtcaccaaccgggcccgcctgaactggtgggagagccgc
gcactgtacggctggacggtgctggtgccgcggaccaaggatcaggccggggagatgagc
gacaagctcgtcggccacggcgccctgccgatcgaggtgcccaccatcgccgtcgaaccg
ccgcgcagccccgcgcagatggagcgtgcggtcaagggtctggtcgacggccggttccag
tgggtcgtgttcacctccaccaacgcggtgcgcgcggtgtgggagaagttcaacgagttc
gggctcgacgcccgcgcgttctccggtgtgaagatcgcctgcgtcggtcaggcgacggca
gagcgggtgcgcgcgttcgggatcaaccccgagctggttccgacgggggagcagtcctcg
ctgggtctgctcgacgagttcccgccgtacgacgacattttcgatccggtgaaccgggtg
ctgctgccgcgcgccgacatcgccaccgagacgctggccgaggggctgcgcgaacgcggt
tgggagatcgaggacgtcaccgcctaccggacggtgcgtgccgcaccgccgccggcctcg
acgcgcgagatgatcaagacgggcggcttcgacgcggtgtgcttcacgtcgagctcgacg
gtgcgcaacctggtcggcatcgccggtaagccgcacgcccgcacgatcgtcgcctgcatc
gggcccaagaccgcggagacggcagcggagttcggcctgcgcgtcgacgtgcagcccgag
gtggccgcggtcggtccgctggtggaggcgctcgccgagcacgccgcccgactgcgcgcc
gagggtgcgctgccgccgccgcgcaagaagagtcgccgccgctga

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