KEGG T00082: MM

Methanosarcina mazei Go1: MM_0338

Entry

MM_0338           CDS       T00082

Name

(GenBank) putative phosphomethylpyrimidine kinase

K21219

hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]

Organism

mma Methanosarcina mazei Go1

Pathway

mma00730

Thiamine metabolism

mma01100

Metabolic pathways

mma01240

Biosynthesis of cofactors

Module

mma_M00896

Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP

mma_M00899

Thiamine salvage pathway, HMP/HET => TMP

Brite

KEGG Orthology (KO) [BR:mma00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    MM_0338
Enzymes [BR:mma01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     MM_0338
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.49  hydroxymethylpyrimidine kinase
     MM_0338
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7  phosphooxymethylpyrimidine kinase
     MM_0338

SSDB

Motif

Pfam:

Phos_pyr_kin ThiP_synth PfkB HK

Other DBs

NCBI-ProteinID:

AAM30034

UniProt:

Q8Q000

Position

complement(445717..447075)

AA seq 452 aa
MRNKMTEKTPMFKTPVVMTIAGSDSGGGAGIAADIKTFAAFGVHGTCAITSVTAQNTTGV
LETFDLAPEAVASQIEAVCTDMDVKWAKTGMLASSEIIKEVAKQVKKHNLSLVLDPVMAA
EAGGDLLKKEALSVLIKELLPLCKVTTPNASEAGALAGVTVKTHEDAKLAARKIADLGVE
SVIVTGGHIDATDLLYEPVSGTFTRIPGTFVKGGTHGSGCTYSASMAACLARGDSTETAA
RKAKTFVEQAILRSVPVGKGVGPVNPLANTLEEKERYLALQDVKEAVSILTYSPDFAKLI
PEVGCNIGMAIPCARTYNEIAAVEGRIIRFREKAIPVGYVNFGASQHVARVILAALRENP
EMRAAMNVKYSEEILEACREINPGISSFDRAEDPGDASTMEWGTSEAIRKYGGMPEVIYD
KGAIGKEPMVRLLGKSASEVAKLAVELARRVK

NT seq 1359 nt +upstreamnt +downstreamnt
atgaggaataaaatgacagaaaaaacccctatgtttaaaactcctgttgtgatgactatc
gctggttctgattcaggagggggagcaggaattgctgctgacatcaagacctttgcagca
ttcggagtccacgggacctgcgccattacttccgtaaccgcccagaatactacaggggtt
cttgaaacatttgatcttgctcctgaagccgttgcgagccagatagaggctgtctgtacc
gacatggatgttaagtgggcaaaaaccggaatgcttgcctcttcagagatcataaaagag
gttgcaaagcaggtaaaaaaacataatctctccctcgtgctcgaccctgtaatggctgct
gaagccggaggagacctgctgaaaaaagaagccctttcagtccttattaaagaactgtta
cctctctgcaaggttacaactccaaacgcctcagaggcgggcgcacttgcaggtgtcact
gtcaagacccatgaagatgcaaaacttgcggcaagaaaaattgcagaccttggggttgaa
tccgttattgttacgggagggcatatcgacgcgactgacctcctttatgaacctgtgtcc
ggcacctttacacgcattccgggcacttttgtaaaaggagggacacatgggtctggatgc
acttattccgcgtcaatggctgcctgccttgcccggggtgacagcacggaaaccgctgcc
agaaaagcaaagacgtttgtggaacaggcgattttgaggagcgtgcctgtaggaaaggga
gtgggacctgtaaatcctctggcaaatacacttgaagaaaaagagcggtacctggctctt
caggacgtaaaagaagcggtttcaatcctcacatacagccctgattttgcaaaactaatc
cctgaggttggctgtaatatagggatggcaatcccatgtgccaggacttataatgaaata
gctgctgtcgaaggcaggataatcaggttcagggaaaaggcaattcccgtcggatacgtt
aatttcggagccagccagcatgttgccagggttattttagcagctctccgcgagaatcct
gaaatgagggctgccatgaatgtgaaatactcggaagaaattcttgaagcatgcagagaa
ataaatcctggaatctcttcttttgacagggctgaagatcctggggatgccagcaccatg
gaatggggaacatcggaggcaattagaaaatacggaggaatgcctgaagtaatctatgat
aaaggagcaataggaaaagaacccatggtcaggctgcttggtaaaagcgcttcagaggtc
gcaaagcttgccgtggaacttgccaggagagtaaaataa

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