KEGG   Mycobacterium marinum E11: MMARE11_16450
Entry
MMARE11_16450     CDS       T04774                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase (large subunit) LeuC
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
mmae  Mycobacterium marinum E11
Pathway
mmae00290  Valine, leucine and isoleucine biosynthesis
mmae00660  C5-Branched dibasic acid metabolism
mmae01100  Metabolic pathways
mmae01110  Biosynthesis of secondary metabolites
mmae01210  2-Oxocarboxylic acid metabolism
mmae01230  Biosynthesis of amino acids
Module
mmae_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mmae00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    MMARE11_16450 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    MMARE11_16450 (leuC)
Enzymes [BR:mmae01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     MMARE11_16450 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     MMARE11_16450 (leuC)
SSDB
Motif
Pfam: Aconitase AcnX
Other DBs
NCBI-ProteinID: CDM75793
Position
1957547..1958968
AA seq 473 aa
MALQTREARTLAEKVWDDHVVVSGRNEAPDLIYIDLHLVHEVTSPQAFDGLRLADRPVRR
PDLTIATEDHNVPTVDIDKPIADPVSRTQVETLRRNCAEFGIRLHPMGDVEQGIVHVVGP
QLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGQ
LPAGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMV
APDETTYEYLRDRPHAPTGAQWDAALGYWQQLRTDPGAVFDTEVHLDAAELSPFVTWGTN
PGQGVPLCATVPDPELIGDDGERQAAEKALAYMDLEPGKAMRDIAVDAVFVGSCTNGRIE
DLRVVAEVLRGRKVAPGVRMLIVPGSMRVRAQAEKEGLGEVFTVAGAEWRQAGCSMCLGM
NPDQLAPGERCAATSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSAPADLN
NT seq 1422 nt   +upstreamnt  +downstreamnt
atggcactgcagacgcgcgaggcgcgcacgctggctgagaaggtctgggacgaccacgtc
gtggtgtccggtcggaacgaggctcccgacctgatctacatcgatctgcatctggtgcat
gaggtcaccagcccgcaggcattcgatggtctgcgcctggccgaccgcccggtgcgacgg
cccgatctgaccatcgccaccgaggaccacaatgtgccgaccgtcgatatcgataagccg
atcgccgatccggtgtctcggacccaggtggagacattgcggcgtaattgcgcggaattc
ggcatccggctgcacccaatgggtgatgtcgagcagggcatcgtgcacgtcgtgggacct
cagttgggcctcactcagccgggaatgaccatcgtctgtggtgacagccacacttcgaca
catggcgcgttcggtgccttggcgatgggcatcggcacttccgaagtcgagcatgtgctc
gcaacacagacgctgccgttgcggccgtttaagacgatggcggtcaatgtggatgggcaa
ctacccgcaggagtgtcggccaaggacatcatccttgcgctgatcgccaagatcggcacc
ggcggtgggcaggggcacgtcatcgaataccggggcagcgccattgaatcgctgtccatg
gaaggccggatgacgatctgcaacatgagcattgaggccggcgcccgagccgggatggtg
gcgccggacgagaccacttacgagtacttgcgagaccggccacacgccccaaccggtgcc
cagtgggatgccgcgcttgggtactggcaacaactgcggaccgatcctggcgccgtcttc
gacaccgaggtccatctcgacgccgccgagctgagcccctttgttacgtggggaaccaat
cccggccagggcgtgccgctttgcgccacggtgcccgatcccgagctcatcggcgatgac
ggcgagcgccaggccgccgagaaagcattggcgtacatggaccttgagccaggaaaagcc
atgcgcgatatcgcggtcgatgccgtgttcgtcgggtcgtgcaccaacggccggatcgag
gatctgcgggtcgtggccgaagtgctgcgtggccgcaaggtcgccccaggggtgcgaatg
ctcatcgttcccggctccatgcgggtgcgtgcccaggccgagaaggagggtctgggtgag
gtcttcacggtcgcgggcgccgaatggcggcaggcgggatgctctatgtgcctagggatg
aaccccgatcagctcgcaccgggggagcgctgtgcggcgacgtccaaccgcaacttcgag
gggcgccagggcaagggcgggcggacacatttggtctcgccggcggtggccgctgcaacc
gcggttcgcggcaccctatccgcgcctgccgatttgaattga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (48)   

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