KEGG   Mycobacterium tuberculosis variant microti: RN08_2489
Entry
RN08_2489         CDS       T04291                                 
Name
(GenBank) pyruvate dehydrogenase E1 component
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
mmic  Mycobacterium tuberculosis variant microti
Pathway
mmic00010  Glycolysis / Gluconeogenesis
mmic00020  Citrate cycle (TCA cycle)
mmic00620  Pyruvate metabolism
mmic00785  Lipoic acid metabolism
mmic01100  Metabolic pathways
mmic01110  Biosynthesis of secondary metabolites
mmic01120  Microbial metabolism in diverse environments
mmic01200  Carbon metabolism
mmic01210  2-Oxocarboxylic acid metabolism
Module
mmic_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:mmic00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    RN08_2489
   00020 Citrate cycle (TCA cycle)
    RN08_2489
   00620 Pyruvate metabolism
    RN08_2489
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    RN08_2489
Enzymes [BR:mmic01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     RN08_2489
SSDB
Motif
Pfam: PDH_E1_M Transketolase_C
Other DBs
NCBI-ProteinID: AMC59916
Position
2509888..2511402
AA seq 504 aa
MATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLA
YKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAA
DQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLA
RMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGV
AMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALE
NARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAV
LEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGPNAGEPTAFGRIFQKSGVAF
RSERQSVGSSCPPEVAARTAGHCARFAAAAVEAVLGPAGHRGSFGHARTVAVLRRPRSVP
ARQRGAGGADGRGQLRRMDARPAQ
NT seq 1515 nt   +upstreamnt  +downstreamnt
atggcgacggtgcgcacgttcaaagaagtgttgcgcgacaagcagatcgggccgcggata
gtcccgatcattcccgacgaggcccgcaccttcgggatggactcctggttcccgtcgcta
aagatctataaccgcaatggccagctgtataccgcggttgacgccgacctgatgctggcc
tacaaggagagcgaagtcgggcagatcctgcacgagggcatcaacgaagccgggtcggtg
ggctcgttcatcgcggccggcacctcgtatgcgacgcacaacgaaccgatgatccccatt
tacatcttctactcgatgttcggcttccagcgcaccggcgatagcttctgggccgcggcc
gaccagatggctcgagggttcgtgctcggggccaccgccgggcgcaccaccctgaccggt
gagggcctgcaacacgccgacggtcactcgttgctgctggccgccaccaacccggcggtg
gttgcctacgacccggccttcgcctacgaaatcgcctacatcgtggaaagcggactggcc
aggatgtgcggggagaacccggagaacatcttcttctacatcaccgtctacaacgagccg
tacgtgcagccgccggagccggagaacttcgatcccgagggcgtgctgcggggtatctac
cgctatcacgcggccaccgagcaacgcaccaacaaggcgcagatcctggcctccggggta
gcgatgcccgcggcgctgcgggcagcacagatgctggccgccgagtgggatgtcgccgcc
gacgtgtggtcggtgaccagttggggcgagctaaaccgcgacggggtggccatcgagacc
gagaagctccgccaccccgatcggccggcgggcgtgccctacgtgacgagagcgctggag
aatgctcggggcccggtgatcgcggtgtcggactggatgcgcgcggtccccgagcagatc
cgaccgtgggtgccgggcacatacctcacgttgggcaccgacgggttcggcttttccgac
actcggcccgccgctcgccgctacttcaacaccgacgccgaatcccaggtggtcgcggtt
ttggaggcgttggcgggcgacggcgagatcgacccatcggtgccggtcgcggccgcccgc
cagtaccggatcgacgacgtggcggctgcgcccgagcagaccacggatcccggtcccggg
cctaacgccggcgagccgaccgcctttggccgaatcttccagaaatctggcgtagctttt
aggagtgaacgacaatcagttggctccagttgcccgcccgaggtcgccgctcgaactgct
ggacactgtgcccgattcgctgctgcggcggttgaagcagtactcgggccggctggccac
cgaggcagtttcggccatgcaagaacggttgccgttcttcgccgacctagaagcgtccca
gcgcgccagcgtggcgctggtggtgcagacggccgtggtcaacttcgtcgaatggatgca
cgacccgcacagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (34)   

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