KEGG   Mus musculus (mouse): 105787Help
Entry
105787            CDS       T01002                                 

Gene name
Prkaa1, AI194361, AI450832, AL024255, AMPKalpha1, C130083N04Rik
Definition
protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
mmu  Mus musculus (mouse)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    105787 (Prkaa1)
   04151 PI3K-Akt signaling pathway
    105787 (Prkaa1)
   04152 AMPK signaling pathway
    105787 (Prkaa1)
   04150 mTOR signaling pathway
    105787 (Prkaa1)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    105787 (Prkaa1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    105787 (Prkaa1)
   04920 Adipocytokine signaling pathway
    105787 (Prkaa1)
   04921 Oxytocin signaling pathway
    105787 (Prkaa1)
  Environmental adaptation
   04710 Circadian rhythm
    105787 (Prkaa1)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    105787 (Prkaa1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    105787 (Prkaa1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     105787 (Prkaa1)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   105787 (Prkaa1)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    105787 (Prkaa1)
  Mitophagy factors
   Other mitophagy factors
    105787 (Prkaa1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
15 A1; 15
AA seq 559 aa AA seqDB search
MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
IFYTPQYLNPSVISLLKHMLQVDPMKRAAIKDIREHEWFKQDLPKYLFPEDPSYSSTMID
DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDS
FLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDI
MAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDE
ITEAKSGTATPQRSGSISNYRSCQRSDSDAEAQGKPSDVSLTSSVTSLDSSPVDVAPRPG
SHTIEFFEMCANLIKILAQ
NT seq 1680 nt NT seq  +upstreamnt  +downstreamnt
atgcgcagactcagttcctggagaaagatggcgacggccgagaagcagaagcacgacggg
cgggtgaagatcggccactacatcctgggggacacgcttggtgtcggcaccttcgggaaa
gtgaaggtgggcaagcacgagttgaccggacataaagtggctgtgaagatactcaaccgg
cagaagattcggagccttgacgtggtgggaaaaatccgccgggagattcagaacctgaag
ctgttcaggcaccctcacatcatcaaactgtaccaggtcatcagtacaccatctgatatt
ttcatggtgatggaatatgtctctggaggagagctatttgattatatctgtaaaaatgga
aggttggacgaaaaggaaagccgccgtctgttccagcagatcctttccggtgtggattat
tgtcacaggcatatggtggtccacagagatttgaaacctgagaacgtcctgcttgatgca
cacatgaatgcaaagatagccgactttggtctttcaaacatgatgtcagatggtgaattt
ttaagaacaagctgtggctcacccaattatgccgcaccagaagtcatttcaggaagattg
tacgcaggccccgaggtggacatctggagcagcggggtcattctctatgctttgctgtgt
ggaaccctcccttttgatgatgaccatgtgccaactctttttaagaagatatgtgatggg
atcttttatacccctcagtacttaaacccttcagtaatcagccttttgaaacatatgctg
caggtggatcccatgaagagggccgcaataaaagatatcagggaacacgagtggtttaaa
caggaccttccgaagtatctctttcctgaggacccatcttatagttcaaccatgatcgat
gacgaagccttgaaagaagtgtgtgagaagttcgagtgttcggaggaggaggtcctcagc
tgcctgtacaacagaaaccaccaggacccactagccgtcgcctaccacctcatcatagac
aacaggagaataatgaatgaagccaaagatttctacctagcaaccagcccacctgactct
ttcctggacgaccaccatttaactcggcctcaccctgaaagagtaccgttcttggttgcc
gaaacaccacgggcccggcacaccctggatgaattaaacccacagaaatccaaacaccaa
ggtgtacggaaggcaaaatggcatttgggaattcgaagtcaaagccgacccaatgatatc
atggcagaagtttgtagagcaatcaagcagttggattatgaatggaaggttgtaaacccc
tattatttgcgtgtacgaaggaagaatcctgtgacaagcacattttccaaaatgagtcta
cagctataccaagtggatagtaggacttacttgttggatttccgtagtattgatgatgag
attacagaagccaaatcagggactgctactccacagagatcgggatccatcagcaactat
cgatcttgccaaaggagtgactctgatgccgaagctcaaggaaagccctcagacgtctcc
cttacctcatctgtcacctccctcgactcctcccctgtcgacgtagctccaagaccagga
agtcatacaatagaattttttgaaatgtgtgcaaatctaattaaaattcttgcacagtaa

  All links  
No link information was found.   
DBGET integrated database retrieval system