KEGG   Mus musculus (mouse): 108079Help
Entry
108079            CDS       T01002                                 

Gene name
Prkaa2, 2310008I11Rik, A830082D05, AMPKalpha2
Definition
protein kinase, AMP-activated, alpha 2 catalytic subunit (EC:2.7.11.1 2.7.11.27 2.7.11.31)
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
mmu  Mus musculus (mouse)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    108079 (Prkaa2)
   04151 PI3K-Akt signaling pathway
    108079 (Prkaa2)
   04152 AMPK signaling pathway
    108079 (Prkaa2)
   04150 mTOR signaling pathway
    108079 (Prkaa2)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    108079 (Prkaa2)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    108079 (Prkaa2)
   04920 Adipocytokine signaling pathway
    108079 (Prkaa2)
   04921 Oxytocin signaling pathway
    108079 (Prkaa2)
  Environmental adaptation
   04710 Circadian rhythm
    108079 (Prkaa2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    108079 (Prkaa2)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    108079 (Prkaa2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     108079 (Prkaa2)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   108079 (Prkaa2)
Mitochondrial biogenesis [BR:mmu03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    108079 (Prkaa2)
  Mitophagy factors
   Other mitophagy factors
    108079 (Prkaa2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
4 C6; 4
AA seq 552 aa AA seqDB search
MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLF
QQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPDYLNRS
VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKACDIMAEVY
RAMKQLGFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDSRSYLLDFKSIDDEVVEQR
SGSSTPQRSCSAAGLHRARSSFDSSTAENHSLSGSLTGSLTGSTLSSASPRLGSHTMDFF
EMCASLITALAR
NT seq 1659 nt NT seq  +upstreamnt  +downstreamnt
atggctgagaagcagaagcacgacgggcgggtgaagatcggacactacgtcctgggggac
accctgggcgtcggcaccttcggcaaagtgaagattggagaacaccaattgacaggccat
aaagtggcagttaagatcttaaatagacagaagattcgcagtttagatgttgttggaaaa
ataaaacgagaaattcaaaatcttaaactctttcgtcatcctcatattatcaaactctac
caggtgatcagcactccgacagacttttttatggtaatggaatatgtgtctggaggtgaa
ttgttcgactacatctgcaaacatgggcgggttgaagaggtggaagcgcgccggctcttc
cagcagatcctgtctgccgtggattactgtcacaggcatatggttgtccatagggacctg
aagccagagaatgtgctgctggatgcccagatgaacgctaagatagctgactttggacta
tctaatatgatgtcagatggtgaatttctacgaactagctgtggatcgccaaattatgca
gcacctgaggtcatctcaggaaggctgtatgcaggtcccgaggtcgatatctggagctgt
ggtgtcatcctgtatgcccttctctgtggcaccctccctttcgatgatgagcacgtgcct
acgctcttcaagaagatccgagggggtgtgttttacatcccagactatctcaaccgttct
gtcgccactctgctgatgcacatgctccaggtggaccccctgaagcgagcgactatcaaa
gacatacgagaacatgaatggtttaaacaggatttgcccagctacctatttcctgaagac
ccctcctacgatgcgaatgtcattgacgatgaggctgtgaaggaagtctgtgagaaattc
gagtgtacagagtcagaagtgatgaatagtctgtatagtggtgaccctcaagaccagctt
gcagtggcttatcatcttatcattgacaatcggagaataatgaaccaagccagtgagttc
tacctcgcctctagtcctccatcaggttcttttatggatgacagcgccatgcatattcct
ccaggcttgaaaccacatccagaaaggatgccgcctctcatcgcagacagccccaaagca
cgctgtccactggatgcactcaacacaacgaagcccaagtctctagctgtgaaaaaagcc
aagtggcatcttggaatccgaagccagagcaaagcgtgtgacattatggctgaagtgtac
cgagctatgaagcagctgggttttgaatggaaggtagtgaatgcataccatcttcgagta
agaagaaaaaacccagtgactggcaactatgtgaaaatgagcttacagctttacctggta
gacagtcggagctatcttctggacttcaaaagcatcgatgatgaggtggtggagcagagg
tctggttcttcaacaccccagcgctcctgttctgctgcgggcctccacagagcacggtca
agttttgattccagcacagctgagaaccactccctttctggctctctcactggctctttg
actggcagcactttgtcctcggcatccccgcgcctgggcagtcacaccatggattttttt
gaaatgtgcgccagtcttatcactgctttagctcgttga

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