KEGG   Mus musculus (mouse): 11421Help
Entry
11421             CDS       T01002                                 

Gene name
Ace, AW208573, CD143
Definition
(RefSeq) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 (EC:3.4.15.1)
  KO
K01283  
peptidyl-dipeptidase A [EC:3.4.15.1]
Organism
mmu  Mus musculus (mouse)
Pathway
Renin-angiotensin system
Renin secretion
Chagas disease (American trypanosomiasis)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Organismal Systems
  Endocrine system
   04924 Renin secretion
    11421 (Ace)
   04614 Renin-angiotensin system
    11421 (Ace)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    11421 (Ace)
  Infectious diseases
   05142 Chagas disease (American trypanosomiasis)
    11421 (Ace)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.15  Peptidyl-dipeptidases
    3.4.15.1  peptidyl-dipeptidase A
     11421 (Ace)
Peptidases [BR:mmu01002]
 Metallo Peptidases
  Family M2
   11421 (Ace)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   11421 (Ace)
Cellular antigens [BR:mmu04090]
 Proteins
  11421 (Ace)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
11 E1; 11 68.84 cM
AA seq 1312 aa AA seqDB search
MGAASGQRGRWPLSPPLLMLSLLVLLLQPSPAPALDPGLQPGNFSPDEAGAQLFAESYNS
SAEVVMFQSTVASWAHDTNITEENARRQEEAALVSQEFAEVWGKKAKELYESIWQNFTDS
KLRRIIGSIRTLGPANLPLAQRQQYNSLLSNMSRIYSTGKVCFPNKTATCWSLDPELTNI
LASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAFWRSWYESPS
FEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYD
MVVPFPDKPNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGR
EVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPG
FHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWR
WGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFV
LQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALD
AKALLEYFQPVSQWLEEQNQRNGEVLGWPENQWRPPLPDNYPEGIDLETDEAKADRFVEE
YDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNS
SIKRIIKKLQNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPLEPDLTNMMA
TSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTDAGDSWRSLYESDNLE
QDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLV
APFPSAPNIDATEAMIKQGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREV
VCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFH
EAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWR
VFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQ
FQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSAS
AMMNYFKPLTEWLVTENRRHGETLGWPEYNWAPNTARAEGSTAESNRVNFLGLYLEPQQA
RVGQWVLLFLGVALLVATVGLAHRLYNIRNHHSLRRPHRGPQFGSEVELRHS
NT seq 3939 nt NT seq  +upstreamnt  +downstreamnt
atgggggccgcgtccggccagcgggggcggtggccgttgtcgcctccgctcttgatgctg
tcgctgctggtgctgttgctgcagccgtcgcccgccccggcactcgaccctggattgcag
ccgggcaacttttccccggacgaggcaggggcgcagcttttcgctgaaagctataactcg
agtgccgaggtggtgatgttccagagcaccgtggccagttgggcgcacgacaccaacatc
acggaggagaacgcgcgacgccaggaggaagcggccctggtcagccaggagtttgcagag
gtctggggcaagaaggccaaggagttgtatgagtccatttggcagaactttactgactca
aagctgcgaaggatcatcggatctattcggaccctaggacctgccaatctgcccctggcc
cagcggcagcagtacaactctctgctaagcaacatgagcagaatctactccactggcaag
gtctgcttccccaacaagactgccacctgctggtccctggacccagagctcaccaacatc
ctggcttcctcacgaagctatgccaagttgttgtttgcctgggagggctggcatgatgct
gtgggtatcccactgaaacccctctatcaagactttactgccatcagtaacgaagcctac
agacaagacgacttctcagacacaggagccttctggcgctcctggtatgagtccccctcc
tttgaggagagtctggaacatatctaccaccaactagagcccctctacctgaacctccat
gcctacgtccgccgcgcactgcaccgccgctatggggacaaatacgtcaatctcaggggg
cctattcctgcccatttgctgggagacatgtgggcccagagctgggagaacatctacgac
atggtagtgcctttcccagacaaacccaacctcgatgtcaccagtacaatggtacagaag
ggctggaacgccacacacatgttccgggtatcagaggaattcttcacctcgctggggctc
tcacccatgcctcctgagttctgggcggagtcaatgctggagaaaccaacggatggacgg
gaggtggtgtgccacgcctctgcctgggacttctacaaccggaaggacttccggattaag
caatgcacacgggtcacgatggaacagctggccacagtacaccacgagatgggccacgtg
cagtactacctccagtacaaggacctgcacgtctctctgcgtagaggtgccaaccctggc
ttccatgaggccattggggatgtgcttgcactctccgtctctacccctgcacatctgcac
aaaatcggcctactggaccatgttaccaatgacatagagagtgacatcaattacctgcta
aagatggccctagagaaaatcgccttcttgccctttggctacctggtggaccagtggcgt
tggggggtcttcagtggacggaccccaccctctcgctacaacttcgactggtggtatctt
cgaaccaagtatcaggggatctgcccaccagttgcccggaatgaaacccattttgatgct
ggagccaagtttcacatcccaaacgtgacaccgtacatcaggtacttcgtgagctttgtg
ctgcagttccagttccatcaagcactgtgcaaggaggcaggccaccagggcccactacac
cagtgtgacatctaccagtccgcccaggcgggggccaagctcaagcaggtgttgcaggct
ggctgctccaggccctggcaggaggtactgaaggacctggtaggctcagatgccctggat
gccaaggcactgctggagtacttccaaccggtcagccagtggctggaagagcagaatcag
cggaatggcgaagtcctaggctggccagagaatcagtggcgtccaccgttacccgacaac
tatccagagggcattgacctagagactgatgaagccaaggctgacaggttcgtggaagag
tatgaccggacagcccaagtgttgttgaacgagtacgcagaggccaactggcaatataac
accaacattaccatagagggcagcaagatcctgcttgagaaaagcacggaggtatccaat
cacaccctgaaatatggcacccgggccaagacatttgatgtgagcaactttcaaaactct
tccatcaagcggatcataaagaagcttcagaacctggaccgggcagtgctgcctcccaag
gaattagaagagtacaaccagatcctgctagacatggagacaacttacagcttatccaac
atttgctacacaaatggcacttgtatgcccctggaacctgatctaacaaacatgatggcc
acatcccggaaatatgaagaattgctatgggcatggaagagctggagagacaaggtgggg
agagccatccttccttttttcccaaagtatgtggagttctccaacaagattgccaagctc
aatggctacacggatgcaggggattcatggagatccttatacgagtctgacaacctggag
caagacctggaaaaactgtaccaggagctgcagccactctacctgaacctgcatgcctat
gtgcgtcgttccctgcaccgccactatgggtccgagtacatcaacctggatggccccatt
cctgcccatctgctagggaacatgtgggcgcagacctggtccaacatctatgatttggtg
gcgcccttcccttccgcccccaatatagatgccacggaagccatgataaagcagggatgg
acacccagaaggatatttaaggaagctgacaatttctttacctccctggggctgttacct
gtgccccctgagttctggaacaagtcgatgttagagaagcccaccgatggaagggaggtg
gtgtgccatccctcagcctgggacttctacaacggcaaggacttcaggatcaagcagtgt
acctctgtgaacatggaggacttggtgatagcgcaccacgaaatgggccacatccagtat
ttcatgcagtacaaagacttacccgtgactttccgggagggtgccaaccctggttttcat
gaagctattggagatataatggctctctcagtgtctacccccaagcatctatacagtctc
aacctgcttagcactgagggcagtggctacgagtatgacatcaactttctaatgaagatg
gccctcgacaagatcgcctttatccccttcagctacctcatcgaccagtggcgctggagg
gtctttgatggaagcatcaccaaggagaactataaccaggagtggtggagcctcaggctg
aagtatcagggtctgtgccccccagtgccaagatcccaaggtgactttgacccagggtcc
aagttccacgttcctgcgaacgtgccatacgtcaggtactttgtcagcttcatcatccag
ttccagttccacgaggcgctgtgtcgcgcagccgggcacacgggtcccctgcacaagtgt
gacatctaccaatccaaggaagcagggaagctcctggcggatgccatgaagctgggctac
agtaagccgtggccagaggccatgaagctgatcacaggccagcctaacatgtcagcctcc
gccatgatgaattacttcaagccactgacagaatggctcgtcaccgagaacaggagacat
ggagagacactgggctggccggagtacaactgggcgccaaacaccgctcgcgcagaaggc
tccaccgcagagtccaaccgcgtcaatttcctgggcctgtacctggagccacagcaggcc
cgcgtgggccagtgggtgctgctcttcctgggcgtcgccctgctcgtggccaccgtgggt
ctcgcccatcggctctacaacatccgtaaccatcacagcctccgccggccccaccgtggg
ccccagtttgggtctgaggtggagctcagacactcctga

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