KEGG   Mus musculus (mouse): 11512Help
Entry
11512             CDS       T01002                                 

Gene name
Adcy6, mKIAA0422
Definition
adenylate cyclase 6 (EC:4.6.1.1)
Orthology
K08046  
adenylate cyclase 6 [EC:4.6.1.1]
Organism
mmu  Mus musculus (mouse)
Pathway
Purine metabolism
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Gap junction
Platelet activation
Circadian entrainment
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
HTLV-I infection
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    11512 (Adcy6)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    11512 (Adcy6)
   04022 cGMP - PKG signaling pathway
    11512 (Adcy6)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    11512 (Adcy6)
  Cell communication
   04540 Gap junction
    11512 (Adcy6)
 Organismal Systems
  Immune system
   04611 Platelet activation
    11512 (Adcy6)
   04062 Chemokine signaling pathway
    11512 (Adcy6)
  Endocrine system
   04911 Insulin secretion
    11512 (Adcy6)
   04912 GnRH signaling pathway
    11512 (Adcy6)
   04913 Ovarian Steroidogenesis
    11512 (Adcy6)
   04915 Estrogen signaling pathway
    11512 (Adcy6)
   04914 Progesterone-mediated oocyte maturation
    11512 (Adcy6)
   04921 Oxytocin signaling pathway
    11512 (Adcy6)
   04918 Thyroid hormone synthesis
    11512 (Adcy6)
   04916 Melanogenesis
    11512 (Adcy6)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    11512 (Adcy6)
   04270 Vascular smooth muscle contraction
    11512 (Adcy6)
  Digestive system
   04970 Salivary secretion
    11512 (Adcy6)
   04971 Gastric acid secretion
    11512 (Adcy6)
   04972 Pancreatic secretion
    11512 (Adcy6)
   04976 Bile secretion
    11512 (Adcy6)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    11512 (Adcy6)
   04961 Endocrine and other factor-regulated calcium reabsorption
    11512 (Adcy6)
  Nervous system
   04724 Glutamatergic synapse
    11512 (Adcy6)
   04727 GABAergic synapse
    11512 (Adcy6)
   04725 Cholinergic synapse
    11512 (Adcy6)
   04723 Retrograde endocannabinoid signaling
    11512 (Adcy6)
  Sensory system
   04742 Taste transduction
    11512 (Adcy6)
   04750 Inflammatory mediator regulation of TRP channels
    11512 (Adcy6)
  Environmental adaptation
   04713 Circadian entrainment
    11512 (Adcy6)
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    11512 (Adcy6)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    11512 (Adcy6)
  Infectious diseases
   05166 HTLV-I infection
    11512 (Adcy6)
Enzymes [BR:mmu01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     11512 (Adcy6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
15; 15 F
AA seq 1168 aa AA seqDB search
MSWFSGLLVPKVDERKTAWGERNGQKRPRHANRASGFCAPRYMSCLKNAEPPSPTPAAHT
RCPWQDEAFIRRAGPGRGVELGLRSVALGFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRL
VQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLTFHAAPAQPQPAYVA
LLTCASVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPHSPSAGLWCP
VFFVYITYTLLPIRMRAAVLSGLGLSTLHLILAWQLNSSDPFLWKQLGANVVLFLCTNAI
GVCTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK
EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAVRENHC
LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRV
HCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNA
YLKEQCIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFR
QMGIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKK
YSRKVDPRFGAYVACALLVFCFICFIQLLVFPYSTLILGIYAAIFLLLLVTVLICAVCSC
GSFFPKALQRLSRNIVRSRVHSTAVGIFSVLLVFISAIANMFTCNHTPIRTCAARMLNLT
PADVTACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNVLLSLLASSVFLHISSIGKLA
MTFILGFTYLVLLLLGPPAAIFDNYDLLLGVHGLASSNETFDGLDCPAVGRVALKYMTPV
ILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHF
LARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIIS
EERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNN
FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKG
YQLECRGVVKVKGKGEMTTYFLNGGPSS
NT seq 3507 nt NT seq  +upstreamnt  +downstreamnt
atgtcatggtttagtggcctcctggttcccaaagtggatgaacggaaaacagcttggggg
gaacgcaatgggcagaagcgcccacgccacgcgaatcgagccagtggcttctgcgcacct
cgctacatgagctgcctcaagaatgcggagccacccagccccactcctgcagctcacact
cggtgcccctggcaggatgaagccttcatcaggagggcgggcccgggcaggggtgtggag
ctggggctgcggtcagtggccttggggtttgacgacactgaggtgaccacaccgatgggc
acagctgaagtggcaccggatacatcgcctcggagcggtccgtcctgctggcaccggctt
gtgcaggtgttccagtctaagcagttccgctctgccaagctggagcggctgtaccagcgg
tacttcttccagatgaaccagagcagcctcacgctgctcatggcggtgctggtgctgctc
atggctgtactgttgactttccacgctgcgcctgcccagcctcagcctgcttacgtggcc
ctgctgacctgtgcctctgtcctttttgtggtactcatggtggtgtgtaaccgacacagc
ttccgccaggactccatgtgggtggtgagctatgtggtcctgggcatcctagcagccgtg
caagtcgggggtgccctggcagccaatccacacagcccctcggcgggcctttggtgcccc
gtgttcttcgtctacatcacctacactcttcttcccattcgcatgcgagccgcagtactc
agcggcctgggcctctctactctgcatttgattttggcctggcagctcaacagcagcgac
cccttcctttggaagcagctcggtgctaacgtggtgctcttcctctgcaccaatgccatc
ggtgtctgcacacactaccctgctgaagtgtctcagcgccaagcctttcaggagacccga
ggttacatccaggcgcggctgcacctgcagcatgagaaccgtcagcaggaacggctgctg
ctatcggtgttgccccagcacgttgccatggagatgaaagaagacatcaacacaaaaaaa
gaggacatgatgttccataagatctacatccagaagcatgataatgtcagcatcctgttt
gcggacattgagggcttcaccagcctggcctcccagtgcactgcacaggaactggtcatg
accttgaatgagctctttgcccggtttgacaagctggctgcggtgagggagaatcactgt
ctgaggatcaagatcttaggagactgttactactgcgtgtcagggctgcccgaggcccgg
gcagatcacgcccactgctgtgtggagatgggggtagacatgatcgaagccatctcgctg
gtgcgtgaggtaacaggtgtgaacgtgaacatgcgtgtgggcatccacagcggacgtgtg
cattgcggcgtccttggcctacggaaatggcagtttgatgtctggtcaaacgatgtgacc
ctggctaaccacatggaggccgggggccgggccggccgcatccacatcactcgggctaca
ctgcagtacttgaacggggactatgaggtggagccaggccgtggtggtgaacgcaatgcg
tacctcaaggagcagtgcattgagaccttcctcatacttggcgccagccaaaaacggaaa
gaggagaaagccatgctggccaagcttcagcggacacgggccaactccatggaaggactg
atgccccgctgggttcctgaccgtgccttctcccggaccaaggactctaaggcattccgc
cagatgggcattgatgattctagcaaagacaaccggggtgcccaagatgctctgaaccct
gaagatgaggtggatgagttcctgggccgagccatcgatgcccgaagcatcgaccaactg
cgtaaggaccatgtgcgccggttcctgctcaccttccagagagaggatcttgagaagaag
tattcacggaaagtagatcctcgcttcggagcctacgtcgcctgtgccctcctggttttt
tgcttcatctgttttatccagctccttgtgttcccatactccaccctgatactcgggatt
tatgccgctatcttcctgctgttgctggtcactgtgctgatctgtgccgtgtgctcctgc
ggttctttcttccccaaggccctgcaacgcctgtcccgcaatattgtccgctcacgggtg
cacagcaccgcggttggaatcttctcggttctgcttgtgttcatctctgccatcgccaac
atgtttacctgtaatcacaccccaataaggacctgcgcggcccggatgctgaacttaaca
ccagcggatgtcaccgcctgccacctacaacagctcaattactctctgggactggatgct
cccctgtgtgagggcaccgcacccacctgcagcttccctgagtacttcgtcgggaacgtg
ctgctgagtcttctagccagctctgtcttcctacacatcagcagcatcggcaagctggcc
atgaccttcatcttggggttcacctacttggtgctgcttttgctgggtcccccggccgcc
atctttgacaactatgatctactgcttggcgtccatggcttggcttcctccaatgagacc
tttgatgggctggactgcccagctgtggggagggtagcgctcaaatatatgacccccgtg
attctgctggtgtttgccctggcactgtatctgcatgcacaacaggtggaatcgactgcc
cgcctggacttcctgtggaagttacaggcaacaggggagaaggaggagatggaggagcta
caggcatacaaccggaggttgctgcataacattcttcccaaggacgtggccgcccacttc
ctggcccgggaacgccgcaacgatgagctgtactaccagtcgtgtgaatgtgtggctgtc
atgtttgcctccatcgccaatttctcggagttctacgtggagctcgaggcaaacaacgag
ggcgtggagtgcctgcggctgctcaatgagatcatcgcagactttgacgagatcatcagt
gaggagagattccggcagttggagaagatcaagaccatcggtagcacctacatggccgcc
tctgggctaaatgccagcacctatgaccaggtcggccgctcacacatcacggcgctggct
gactatgccatgcggctcatggagcagatgaaacacatcaatgaacactctttcaacaat
ttccagatgaagatcgggttgaacatgggtccggttgtagcaggcgtcattggggcccga
aagccacagtatgacatctggggaaataccgtgaatgtttccagtcgtatggacagcact
ggagttcctgaccgaatacaggtgactacggacctataccaggttctagctgccaagggc
taccagctggagtgtcgaggggtggtcaaggtgaagggaaagggggagatgaccacctac
ttcctcaacgggggccccagcagttag

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