KEGG T01002: 11789

Mus musculus (mouse): 11789

Entry

11789 CDS T01002

Gene name

Apc, AI047805, AU020952, AW124434, CC1, Min, mAPC

Definition

adenomatosis polyposis coli

Orthology

K02085

adenomatosis polyposis coli protein

Organism

mmu Mus musculus (mouse)

Pathway

mmu04310	Wnt signaling pathway
mmu04390	Hippo signaling pathway
mmu04810	Regulation of actin cytoskeleton
mmu05166	HTLV-I infection
mmu05200	Pathways in cancer
mmu05210	Colorectal cancer
mmu05213	Endometrial cancer
mmu05217	Basal cell carcinoma

Class

Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:mmu04310]
Environmental Information Processing; Signal transduction; Hippo signaling pathway [PATH:mmu04390]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:mmu04810]
Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200]
Human Diseases; Cancers; Colorectal cancer [PATH:mmu05210]
Human Diseases; Cancers; Basal cell carcinoma [PATH:mmu05217]
Human Diseases; Cancers; Endometrial cancer [PATH:mmu05213]
Human Diseases; Infectious diseases; HTLV-I infection [PATH:mmu05166]

SSDB

Motif

Pfam:

APC_basic EB1_binding APC_crr Arm SAMP Suppressor_APC APC_15aa

Other DBs

NCBI-GI:

NCBI-GeneID:

MGI:

Ensembl:

UniProt:

Position

18 B1; 18 18.53 cM

AA seq 2842 aa
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDETM
TSGQIDLLERLKEFNLDSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRRT
FVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQT
DMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRVRQLLQSQAAEA
ERSSQSRHDAASHEAGRQHEGHGVAESNTAASSSGQSPATRVDHETASVLSSSGTHSAPR
RLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLHG
NDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWE
WQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVD
CEMYGLTNDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQ
VIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTEN
KADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCL
QTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGS
AAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPK
ASHRSKQRHKQNLYGDYAFDANRHDDSRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLD
SSRSEKDRSLERERGIGLSAYHPTTENAGTSSKRGLQITTTAAQIAKVMEEVSAIHTSQD
DRSSASTTEFHCVADDRSAARRSSASHTHSNTYNFTKSENSNRTCSMPYAKVEYKRSSND
SLNSVTSSDGYGKRGQMKPSVESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELD
TPINYSLKYSDEQLNSGRQSPSQNERWARPKHVIEDEIKQNEQRQARSQNTSYPVYSENT
DDKHLKFQPHFGQQECVSPYRSRGTSGSETNRMGSSHAINQNVNQSLCQEDDYEDDKPTN
YSERYSEEEQHEEEEERPTNYSIKYNEEKHHVDQPIDYSLKYATDISSSQKPSFSFSKNS
SAQSTKPEHLSPSSENTAVPPSNAKRQNQLRPSSAQRNGQTQKGTTCKVPSINQETIQTY
CVEDTPICFSRCSSLSSLSSADDEIGCDQTTQEADSANTLQTAEVKENDVTRSAEDPATE
VPAVSQNARAKPSRLQASGLSSESTRHNKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETP
LVFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPP
PPQTVQAKREVPKSKVPAAEKRESGPKQTAVNAAVQRVQVLPDVDTLLHFATESTPDGFS
CSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPEESNENQDKEVEKPDSEKD
LLDDSDDDDIEILEECIISAMPTKSSRKAKKLAQTASKLPPPVARKPSQLPVYKLLPAQN
RLQAQKHVSFTPGDDVPRVYCVEGTPINFSTATSLSDLTIESPPNELATGDGVRAGIQSG
EFEKRDTIPTEGRSTDDAQRGKISSIVTPDLDDNKAEEGDILAECINSAMPKGKSHKPFR
VKKIMDQVQQASSTSSGANKNQVDTKKKKPTSPVKPMPQNTEYRTRVRKNTDSKVNVNTE
ETFSDNKDSKKPSLQTNAKAFNEKLPNNEDRVRGSFALDSPHHYTPIEGTPYCFSRNDSL
SSLDFDDDDVDLSREKAELRKGKESKDSEAKVTCRPEPNSSQQAASKSQASIKHPANRAQ
SKPVLQKQPTFPQSSKDGPDRGAATDEKLQNFAIENTPVCFSRNSSLSSLSDIDQENNNN
KESEPIKEAEPANSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQE
CISSAMPKKKRPSRLKSESEKQSPRKVGGILAEDLTLDLKDLQRPDSEHAFSPDSENFDW
KAIQEGANSIVSSLHQAAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT
SNKGPRILKPGEKSTLEAKKIESENKGIKGGKKVYKSLITGKIRSNSEISSQMKQPLPTN
MPSISRGRTMIHIPGLRNSSSSTSPVSKKGPPLKTPASKSPSEGPGATTSPRGTKPAGKS
ELSPITRQTSQISGSNKGSSRSGSRDSTPSRPTQQPLSRPMQSPGRNSISPGRNGISPPN
KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQLSQQNLTKQASLSKNASSIPRSESASKG
LNQMSNGNGSNKKVELSRMSSTKSSGSESDRSERPALVRQSTFIKEAPSPTLRRKLEESA
SFESLSPSSRPDSPTRSQAQTPVLSPSLPDMSLSTHPSVQAGGWRKLPPNLSPTIEYNDG
RPTKRHDIARSHSESPSRLPINRAGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES
SEKAKSEDERHVSSMPAPRQMKENQVPTKGTWRKIKESDISPTGMASQSASSGAASGAES
KPLIYQMAPPVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGSSSIKDSKDT
HGKQSVGSGSPVQTVGLETRLNSFVQVEAPEQKGTEAKPGQSNPVSIAETAETCIAERTP
FSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVSTNTKKRDSKTD
STESSGAQSPKRHSGSYLVTSV

NT seq 8529 nt +upstreamnt +downstreamnt
atggctgcagcttcatatgatcagttgttaaagcaagttgaggcactgaagatggagaac
tcaaatcttcgacaagagctagaagataattccaatcatcttacaaaactggaaactgag
gcatctaatatgaaggaagtacttaagcagctacagggaagtattgaagatgagactatg
acttctggacagattgacttactagagcgtcttaaagaatttaacttagatagtaatttc
cccggagtgaaactacgctcaaaaatgtcccttcgctcctacggaagtcgggaaggatct
gtatccagccgttcaggagaatgcagtcctgtccccatggggtcattcccaagaagaaca
tttgtaaatggaagcagagagagtactgggtatctagaagagcttgaaaaagaaagatca
ttactccttgctgatcttgacaaagaagagaaggaaaaggactggtattatgctcaactt
cagaacctcacaaaaagaatagatagcctgcctttaactgaaaatttttccttacagaca
gacatgacaagacggcagctggagtatgaagcaaggcagatcagggctgcaatggaggag
cagcttggcacctgccaggacatggagaagcgtgcacagcgaagaatagccaggatccag
caaatagaaaaggacatactgcgcgtgcgccagcttttacagtcccaggcggcggaagcg
gagaggtcatctcagagcaggcatgatgctgcctcccatgaagctggccggcagcacgaa
ggccacggagtggcagaaagcaacaccgcagcctccagtagtggtcagagtccagctaca
cgtgtggatcacgaaacagccagtgttttgagttctagcggcacgcactctgctcctcga
aggttgacaagtcatctggggacaaaggtggaaatggtgtattccttgttgtcaatgctt
ggtactcatgataaggacgatatgtcacgaactttgctagctatgtccagctcccaagac
agctgtatatccatgcggcagtctggatgtcttcctctcctcatccagcttttacatggc
aatgacaaagactctgtattgttgggaaattcccggggcagtaaagaggctcgggccagg
gccagtgcagcactccacaacatcattcactcacagcctgatgacaagagaggcaggcgt
gaaatccgagtccttcatcttttggaacagatacgagcttactgtgaaacctgttgggag
tggcaggaagcccacgaacaaggcatggaccaggacaaaaacccaatgccagctcctgtt
gagcatcagatctgtcctgctgtgtgtgttctaatgaagctttcatttgatgaagagcat
aggcatgcaatgaatgaacttgggggactgcaggccattgcagagttattgcaggtggac
tgtgagatgtatgggcttactaatgaccactacagtgttactttaagacggtatgctgga
atggctttgacaaacttgacctttggagatgttgccaacaaggctacgctgtgttctatg
aaaggctgcatgagagcacttgtggcccagttaaaatctgagagtgaagacttacagcag
gttattgcaagtgttttgaggaatttgtcttggcgagcagatgtaaatagcaaaaagacg
ttgagagaagttggaagtgtgaaagcattgatggaatgtgctttggaagttaaaaaggaa
tcaaccctcaaaagcgttttgagtgccttatggaacctgtctgcacactgcactgagaat
aaggctgacatctgtgctgtggatggagcactggcatttctggttggcaccctcacttac
cggagccagacaaatactttagccattattgaaagtggaggtgggatattacggaatgtg
tccagcttgatagctacaaacgaagaccacaggcaaatcctaagagagaacaattgccta
caaactttattacagcacttgaaatctcacagcttgacaatagtcagtaatgcatgtgga
actttgtggaatctctcagcaagaaatcctaaagaccaggaagccttgtgggacatgggg
gcagtgagcatgctcaagaacctcattcattccaagcacaaaatgattgccatgggaagt
gcagcagctttaaggaatctcatggcaaacagacctgcaaagtataaggatgccaatatc
atgtctcccggctcaagtctgccatcccttcacgttaggaaacagaaagctctagaagct
gagctagatgctcagcatttatcagaaaccttcgacaacattgacaacctaagtcccaag
gcctctcaccggagtaagcagagacacaagcagaatctttatggtgactatgcttttgac
gccaatcgacatgatgatagtaggtcagacaatttcaatactggaaacatgactgttctt
tcaccatatttaaatactacggtattgcccagctcttcttcctcaaggggaagtttagac
agttctcgttctgagaaagacagaagtttggagagagagcgaggtattggcctcagtgct
taccatccaacaacagaaaatgcaggaacctcatcaaaacgaggtctgcagatcactacc
actgcagcccagatagccaaagttatggaagaagtatcagccattcatacctcccaggac
gacagaagttctgcttctaccaccgagttccattgtgtggcagacgacaggagtgcggca
cgaagaagctctgcctcccacacacactcaaacacatacaacttcactaagtcggaaaat
tcaaataggacatgctctatgccttatgccaaagtggaatataaacgatcttcaaatgac
agtttaaatagtgtcactagtagtgatggatatggtaaaagaggccaaatgaaaccctca
gttgaatcctattctgaagatgatgaaagtaaattttgcagttatggtcagtatccagct
gacctagcccataagatacacagtgcaaatcatatggatgataatgatggagaactggat
acaccaataaattacagtcttaaatattcagatgagcagttgaactcaggaaggcagagt
ccctcacagaatgaaaggtgggcaagaccaaagcatgtgatagaagatgaaataaagcaa
aacgagcaaagacaagcaagaagccagaacaccagttatcctgtctattctgagaatacc
gatgacaaacacctcaaattccaaccacattttggacaacaagaatgtgtttccccatat
aggtcaaggggaaccagtggttcagaaacaaatcgaatgggttctagtcatgcaattaat
caaaatgtaaaccagtctctgtgtcaggaagatgattatgaagatgataaacctaccaac
tacagtgaacgttattctgaggaagaacaacatgaagaagaagaagagagaccgacaaat
tatagcataaaatataatgaagagaaacatcatgtggatcagcctattgattatagttta
aaatatgccactgacatttcttcctcacaaaaaccatcattttcattctcaaagaattca
tcagcacaaagcactaaacctgaacatctctctccaagcagcgagaatacagctgtacct
ccatctaatgccaaaaggcagaatcagctgcgtccaagttcagcacaaagaaatggccag
actcaaaaaggcactacttgcaaagtcccctccatcaaccaagaaacaatacagacttac
tgcgtagaagacaccccaatatgtttttcaaggtgcagttcattatcatcactgtcatca
gctgacgatgaaataggatgtgatcagacaacacaggaagcagattctgctaatactctg
cagacagcagaagtaaaagagaatgatgtaactcggtcagctgaagatcctgcaactgaa
gttccagcagtgtcccagaatgctagagccaaacccagccgactccaggcttctggctta
tcttcagaatcaaccaggcataataaagctgttgagttttcttcaggagccaagtctccc
tccaaaagtggtgctcagacacccaaaagtcccccagaacactatgtccaggagactccg
ctcgtattcagcaggtgtacttctgtcagctcccttgacagttttgagagtcgctccatt
gccagctctgttcagagtgagccatgtagtggaatggtgagtggcatcataagccccagt
gaccttccagatagtcctgggcagaccatgccaccaagcagaagcaaaacccctccacct
cctccacagacagtgcaggccaagagagaggtgccaaaaagtaaagtccctgctgctgag
aagagagagagtgggcctaagcagactgctgtaaatgctgccgtgcagagggtgcaggtc
cttccagacgtggatactttgttacacttcgccacagaaagtactccagacgggttttct
tgttcctccagcctaagtgctctgagcctggatgagccatttatacagaaagatgtagaa
ttaagaatcatgcctccagttcaggaaaacgacaatgggaatgaaactgaatcagaacag
cctgaggaatcaaatgaaaaccaggataaagaggtagaaaagcctgactctgaaaaagac
ttattagatgattctgatgacgatgatattgaaatattagaagaatgtattatttcagcc
atgccaacaaagtcatcacgcaaagccaaaaaactagcccagactgcttcaaaattacct
ccacctgtggcaaggaaaccaagtcagctacctgtgtataaacttctgccagcacagaat
aggctgcaggcacaaaaacatgttagctttacaccaggggatgatgtgccccgggtgtac
tgtgtagaagggacacctataaacttttccacagcaacgtctctaagtgatctgacaata
gagtcccctccaaatgaattggctactggagatggggtcagagcgggtatacagtcaggt
gaatttgaaaaacgagataccattcctacagaaggcagaagtacagatgatgctcagcga
ggaaaaatctcatctatagttacaccagacctggatgacaacaaagcagaggaaggagat
attcttgcagaatgtatcaattctgctatgcccaaaggaaaaagccacaagcctttccga
gtgaaaaagataatggaccaagtccaacaagcatcctcgacttcatctggagctaacaaa
aatcaagtagacactaagaaaaagaagcctacttcaccagtaaagcccatgccacaaaat
actgaatatagaacgcgtgtgagaaagaatacagactcaaaagttaatgtaaatactgaa
gaaactttctcagacaacaaagactcaaagaaaccaagcttacaaaccaatgccaaggcc
ttcaatgaaaagctacctaacaatgaagacagagtgcgggggagcttcgccttggactca
ccgcatcactacacccctattgaggggacgccgtactgcttttcccgaaatgactccttg
agttctctggattttgatgatgacgatgttgacctttccagggaaaaggccgagttaaga
aagggcaaagaaagcaaggattccgaagccaaagttacctgccgcccagaaccaaactca
agccagcaggcagctagtaagtcacaagccagtataaaacatccagcaaacagagcacag
tccaaaccagtgctgcagaaacagcccactttcccccagtcctccaaagacggaccagat
agaggggcagcaactgacgaaaaactgcagaattttgctattgaaaatactccagtttgc
ttttctcgaaattcctctctgagttcccttagtgacattgaccaggaaaacaacaataac
aaagaaagtgaaccaatcaaagaagctgaacctgccaactcacaaggagagcccagtaag
cctcaggcatccgggtatgctcccaagtccttccacgtcgaagacacccctgtctgtttc
tcaagaaacagctctctcagttctcttagcattgactctgaggacgacctgttacaggag
tgtataagttctgccatgccaaaaaagaaaaggccttcaagactcaagagtgagagcgaa
aagcagagccctagaaaagtgggtggcatattagctgaagacctgacgcttgatttgaaa
gatctacagaggccagattcagaacacgctttctcccccgactcagaaaattttgactgg
aaagctattcaggaaggcgcaaactccatagtaagtagtttgcaccaagctgctgcagcc
gccgcgtgcttatctagacaagcgtcatccgactcagattccattctgtcactaaagtcc
ggcatttctctgggatcgccttttcatcttacacctgatcaagaggaaaagccattcaca
agcaataaaggcccaagaattctcaaacctggagagaaaagcacattagaagcaaaaaaa
atagaatctgaaaacaaaggaatcaaaggcgggaaaaaggtttataaaagcttgattacg
ggaaagattcgctccaattcagaaatttccagccaaatgaaacaacccctcccgacaaac
atgccttcaatctcaagaggcaggacgatgattcacatcccagggcttcggaatagctcc
tctagtacaagccctgtctctaagaaaggcccacccctcaagactccagcctctaaaagc
cccagtgaagggccgggagctaccacttctcctcgaggaactaagccagcaggaaagtca
gagcttagccctatcaccaggcaaacttcccaaatcagtgggtcaaataaggggtcttct
agatcaggatctagagactccactccctcaagacctacacagcaaccattaagtaggcca
atgcagtctccagggcgaaactcaatttcccctggtagaaatggaataagccctcctaac
aaactgtctcagctgcccagaacatcatctcccagtactgcttcaactaagtcctccggt
tctgggaaaatgtcatatacatccccaggtagacagctgagccaacaaaatcttaccaaa
caagcaagtttatccaagaatgccagcagtatccccagaagtgagtcggcatctaaagga
ctgaatcagatgagtaacggcaatgggtcaaataaaaaggtagaactttctagaatgtct
tcaactaaatcaagtggaagtgaatcagacagatcagaaaggcctgcattagtacgccag
tctactttcatcaaagaagccccaagcccaaccctgaggaggaaactggaggaatctgcc
tcatttgaatccctttctccatcttctagaccagattctcccaccaggtcgcaggcacag
accccagttttaagcccttcccttcctgatatgtctctgtccacacatccatctgttcag
gcaggtgggtggcgaaagctcccgcctaatctcagccccactatcgagtataatgacgga
aggcccacaaaacggcatgatattgcacgctcccattctgaaagtccttccagactacca
atcaaccgggcgggaacctggaagcgtgaacacagcaaacattcctcgtcccttcctcga
gtgagtacttggagaagaactggaagctcatcttctattctttctgcttcatcagagtcc
agtgaaaaagcaaaaagtgaggatgaaaggcatgtgagctccatgccagcacccagacag
atgaaggaaaaccaggtgcccaccaaaggaacatggaggaaaatcaaggaaagtgacatt
tctcccacaggcatggcttctcagagcgcttcctcaggtgctgccagtggtgctgaatcc
aagcctctgatctatcagatggcacctcctgtctctaaaacagaggatgtttgggtgaga
attgaggactgccccattaacaaccctagatctggacggtcccccacaggcaacaccccc
ccagtgattgacagtgtttcagagaagggaagttcaagcattaaagattcaaaagacacc
catgggaaacagagtgtgggcagtggcagtcctgtgcaaaccgtgggtctggaaacccgc
ctcaactcctttgttcaggtagaggccccagaacagaaaggaactgaggcaaaaccagga
cagagtaacccagtctctatagcagagactgctgagacgtgtatagcagagcgtacccct
ttcagttccagtagctccagcaagcacagctcacctagcgggactgttgctgccagagtg
acaccttttaattacaaccctagccctaggaagagcagcgcagacagcacttcagcccgg
ccgtctcagatccctacgccagtgagcaccaacacgaagaagagagattcgaagactgac
agcacagaatccagtggagcccaaagtcctaaacgccattccgggtcttacctcgtgacg
tctgtttaa

All links

Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (9)   
   UniGene (1)   
   ENSEMBL-MMU (1)   
   MGI-MMU (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (33)   
   RefSeq(nuc) (1)   
   GenBank (16)   
   EMBL (16)   
Protein domain (7)   
   Pfam (7)   
All databases (67)   

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