KEGG   Mus musculus (mouse): 11792Help
Entry
11792             CDS       T01002                                 

Gene name
Apex1, APE, Apex, HAP1, Ref-1
Definition
(RefSeq) apurinic/apyrimidinic endonuclease 1 (EC:4.2.99.18)
  KO
K10771  
AP endonuclease 1 [EC:4.2.99.18]
Organism
mmu  Mus musculus (mouse)
Pathway
Base excision repair
Module
BER complex
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Genetic Information Processing
  Replication and repair
   03410 Base excision repair
    11792 (Apex1)
Enzymes [BR:mmu01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.18  DNA-(apurinic or apyrimidinic site) lyase
     11792 (Apex1)
DNA repair and recombination proteins [BR:mmu03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    AP endonucleases
     11792 (Apex1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
14 26.3 cM; 14 C3
AA seq 317 aa AA seqDB search
MPKRGKKAAADDGEEPKSEPETKKSKGAAKKTEKEAAGEGPVLYEDPPDQKTSPSGKSAT
LKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLTHQYWSA
PSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFESFVLVTAYVPNAGRGLVR
LEYRQRWDEAFRKFLKDLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFG
ELLQAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIR
SKALGSDHCPITLYLAL
NT seq 954 nt NT seq  +upstreamnt  +downstreamnt
atgccaaagcggggaaagaaagcggcggccgacgacggggaagaacccaagtcggagcca
gagaccaagaagagtaagggggcagcaaagaaaaccgagaaggaggccgcgggagagggc
cctgtcctgtacgaggaccctccagatcagaaaacctcacccagtggcaaatctgccaca
ctcaagatatgctcctggaatgtggatgggcttcgagcctggattaaaaagaaaggtttg
gattgggtaaaggaagaagcaccagatatcttgtgcctccaagagaccaagtgctcggag
aacaaactcccggctgaactgcaagagctgcctggactcacccatcagtactggtcagct
ccgtcagacaaagaaggatacagtggtgtgggcctactttcccgccagtgcccgctaaaa
gtctcttatggcattggcgaggaagaacatgatcaagaaggccgggtgattgtggctgaa
tttgagtcctttgtcctggtaacagcctatgttcccaatgcaggcaggggtctggtaaga
ctggaataccgacagcgttgggatgaagccttccgaaagtttctaaaggacttggcttcc
agaaagcctcttgtgctatgtggggatctcaatgtggctcatgaagaaattgacctccgt
aaccccaaaggaaacaaaaagaatgctggctttactccccaggagcgccaaggttttggg
gaactgctacaagctgtaccattggctgacagcttccggcatctctaccccaacactgct
tacgcttacactttctggacttacatgatgaatgcccgctctaagaatgttggttggcgc
cttgattactttttgctttcccactctcttttacctgcattgtgtgacagcaagatccgg
tccaaggctcttggcagtgaccactgtcccatcaccctttacctagcactgtga

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