KEGG   Mus musculus (mouse): 12294Help
Entry
12294             CDS       T01002                                 

Gene name
Cacna2d3, Cacnad3
Definition
calcium channel, voltage-dependent, alpha2/delta subunit 3
Orthology
K04860  
voltage-dependent calcium channel alpha-2/delta-3
Organism
mmu  Mus musculus (mouse)
Pathway
MAPK signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Oxytocin signaling pathway
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    12294 (Cacna2d3)
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    12294 (Cacna2d3)
  Circulatory system
   04260 Cardiac muscle contraction
    12294 (Cacna2d3)
   04261 Adrenergic signaling in cardiomyocytes
    12294 (Cacna2d3)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    12294 (Cacna2d3)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    12294 (Cacna2d3)
   05414 Dilated cardiomyopathy (DCM)
    12294 (Cacna2d3)
Ion channels [BR:mmu04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-2 delta
   12294 (Cacna2d3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
14; 14 B
AA seq 1091 aa AA seqDB search
MAGPGSLCCASRGASALLATALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKY
SGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKIMEEMFHKKSEAVRRLVEAAEEAHLKH
EFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYN
KDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFD
CRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIITYNEE
LHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSI
CSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQ
ISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLADDQGLVLMTTVA
MPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELR
PLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVM
TNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDL
HPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSD
KGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIAGS
FVYSIPFSTGTVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCAS
LDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEVEGAVMNKLLTMGSFKRITL
YDYQAMCRANKESSDSAHGLLDPYKAFLSAAKWIMTELVLFLVEFNLCSWWHSDMTAKAQ
KLKQTLEPCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCE
SVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGASSLQAQAALL
LLPLVSSLFSR
NT seq 3276 nt NT seq  +upstreamnt  +downstreamnt
atggccgggccgggctcgctgtgctgcgcgtcccggggggcctcggcgctcctagccacc
gcgcttctctacgccgctctgggggacgtggtgcgctccgagcagcagatcccgctctcc
gtagtgaagctgtgggcctccgcttttggtggggagataaaatccatcgctgccaagtac
tcgggctcccagcttctgcaaaagaaatacaaagagtatgagaaggacgttgccattgaa
gaaatcgacggtctccaactggtgaagaagttggctaaaatcatggaggagatgttccac
aagaagtccgaggcagtgaggcgtcttgtggaggctgcagaggaggcacacctgaaacat
gaatttgatgctgacttgcagtatgaatacttcaatgctgtgctgatcaacgagagggac
aaagacgggaactttttggaattgggaaaggaattcatcttagcccccaatgaccatttt
aataatttgcctgtgaacatcagtctgagtgatgtgcaagtgccaacgaacatgtacaac
aaagatcctgccattgtcaatggagtgtattggtctgaatctctaaacaaagtttttgtg
gataactttgatcgggatccgtctctcatatggcagtactttggaagtgcaaagggcttt
ttcagacagtacccagggattaaatgggaaccagatgagaatggagtcattgcctttgac
tgcaggaacagaaaatggtacatccaggcagcgacttctccaaaggatgttgtcattttg
gtggacgtcagtgggagcatgaaaggactccgcttgaccatcgccaagcaaacagtgtcc
tcaatactggatactctgggtgatgatgacttcttcaacatcatcacgtataacgaagag
cttcactatgtggaaccttgtctgaacggaacactggttcaagctgacaggaccaacaag
gagcacttcagggagcatttggacaaactttttgccaaagggattggaatgctggatatc
gcactgaacgaggccttcaacatactgagcgatttcaaccacactggacaaggaagcatt
tgcagccaggccatcatgctcataactgatggggcagtggacacctatgataccatcttt
gcaaaatataattggccagaccgaaaggttcgaatctttacttacctcattggacgggag
gctgcttttgccgacaatctcaagtggatggcttgtgctaacaaaggatttttcacccag
atctccaccttggctgatgtgcaggaaaatgtcatggaatacctccatgtgcttagccga
cctaaagtcattgaccaggagcatgatgtggtgtggaccgaagcgtacattgacagcacc
ctccctcaggctcaaaagcttgctgatgatcagggcctcgtcttgatgaccacggtggcc
atgcctgtgtttagtaagcagaacgaaactaggtcaaagggcattcttctgggtgtggtt
ggcacagatgtcccagttaaagagcttctgaagaccatccccaaatacaagttaggaatt
catggttacgccttcgccatcacgaataatggatatatcctgacgcacccggagctcagg
ccactgtatgaagaaggaaaaaaacggaggaaacccaactacagtagtgtggatctctct
gaagtcgagtgggaagaccgggatgatgtgttacgaaatgccatggtaaatcggaagact
gggaaattctccatggaagtgaagaagaccgtggacaaagggaaacgggttttggtgatg
accaatgactactactatacagacatcaagggtactcctttcagtttaggtgtggcgctc
tccaggggccatgggaaatacttcttccgagggaatgtaaccattgaagaaggcctccat
gacttagaacatcctgacgtgtccttggcagatgaatggtcctactgcaacactgacctg
cacccagagcaccgccatctatctcaactggaagccattaagctctacctcaaaggcaag
gagcctctgcttcaatgtgacaaagaattgattcaagaagtcctttttgatgctgtggtg
agcgcccctattgaagcctattggacgagcctggccctcaacaaatctgagaattctgac
aagggtgtagaggtcgccttcctcggcactcgcacaggcctctcaagaatcaacctgttt
gtgggggccgaacaactcaccaatcaggactttctgaaggctggagacaaagagaacatt
tttaatgccgatcatttccctctctggtacagaagagctgccgagcagatcgcaggaagc
tttgtctattccatccccttcagcacaggaacagtcaacaaaagcaatgtggtgacagca
agtacctccatccagctcctggatgagcggaaatctcccgtggtggcagctgtaggcatt
cagatgaaacttgaattcttccaaaggaagttctggactgccagcagacagtgtgcctcc
ctggatggcaaatgctccataagctgcgatgacgagactgtgaactgttaccttatagac
aataacggattcattctggtgtctgaagactacacacagactggagatttttttggtgag
gtggaaggagctgtcatgaacaagttgttaacaatgggttcctttaaaagaataaccttg
tacgactaccaagccatgtgtagagccaacaaggagagcagtgacagtgcccatggactt
ctggacccctataaggcctttctctctgcagccaagtggataatgacggaacttgtcttg
ttcctggtggagtttaacctgtgcagttggtggcactccgacatgacagctaaagcccag
aaactgaaacagaccctggaaccttgtgatactgaatacccagcctttgtttctgaacgc
accatcaaggagaccacagggaacattgcttgcgaagactgctccaagtccttcgtcatc
cagcaaatcccgagtagcaatctgttcatggtggtggtggacagtagctgtctctgtgag
tccgtggctcctataaccatggcacccattgaaatcaggtataatgaatcccttaagtgt
gaacggttaaaggctcagaagatcagacgacgtccagaatcctgccacggcttccatcct
gaggagaatgcaagagagtgtgggggtgcatcgagtcttcaggcccaggcggccttgctg
ctgctgcccctggtttcgagtctcttctcaaggtga

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