KEGG   Mus musculus (house mouse): 13106
Entry
13106             CDS       T01002                                 
Symbol
Cyp2e1, CYPIIE1, Cyp2e
Name
(RefSeq) cytochrome P450, family 2, subfamily e, polypeptide 1
  KO
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00140  Steroid hormone biosynthesis
mmu00590  Arachidonic acid metabolism
mmu00591  Linoleic acid metabolism
mmu00980  Metabolism of xenobiotics by cytochrome P450
mmu00982  Drug metabolism - cytochrome P450
mmu00983  Drug metabolism - other enzymes
mmu01100  Metabolic pathways
mmu04932  Non-alcoholic fatty liver disease
mmu04936  Alcoholic liver disease
mmu05204  Chemical carcinogenesis - DNA adducts
mmu05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    13106 (Cyp2e1)
   00590 Arachidonic acid metabolism
    13106 (Cyp2e1)
   00591 Linoleic acid metabolism
    13106 (Cyp2e1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    13106 (Cyp2e1)
   00982 Drug metabolism - cytochrome P450
    13106 (Cyp2e1)
   00983 Drug metabolism - other enzymes
    13106 (Cyp2e1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    13106 (Cyp2e1)
   05208 Chemical carcinogenesis - reactive oxygen species
    13106 (Cyp2e1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    13106 (Cyp2e1)
   04932 Non-alcoholic fatty liver disease
    13106 (Cyp2e1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:mmu00199]
    13106 (Cyp2e1)
Cytochrome P450 [BR:mmu00199]
 Cytochrome P450, animal type
  CYP2 family
   13106 (Cyp2e1)
SSDB
Motif
Pfam: p450 DUF6361
Other DBs
NCBI-GeneID: 13106
NCBI-ProteinID: NP_067257
MGI: 88607
Ensembl: ENSMUSG00000025479
UniProt: Q05421
Position
7:140343732..140354903
AA seq 493 aa
MAVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKL
AKRFGPVFTLHLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGP
TWKDVRRFSLSILRDWGMGKQGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVI
ADILFNKRFDYDDKKCLELMSLFNENFYLLSTPWIQAYNYFSDYLQYLPGSHRKVMKNVS
EIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQEPMYTMENISVTLADLFFAG
TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYMDAVVHEIQRF
INLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGK
FKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTIGFGS
IPREFKLCVIPRS
NT seq 1482 nt   +upstreamnt  +downstreamnt
atggcggttcttggcatcaccgttgccttgcttgtctggatcgccaccctcctcctcgta
tccatctggaaacagatctatagaagttggaacctgcccccaggacctttcccaattcct
ttctttggaaacatttttcagctggatttgaaggatattcccaagtctttaaccaagttg
gcaaagcgcttcgggccagtgttcacactgcacctgggtcagaggcgcatcgtggtcctg
catggctacaaggctgtcaaggaggtgctactgaaccacaagaatgagttctctggccga
ggggacattcctgtgttccaggagtacaagaacaaggggattattttcaataatggaccc
acatggaaggacgtgcggaggttttccctaagtatcctccgtgactggggaatggggaaa
cagggtaatgaggcccgcatccaaagagaggcacacttcctggtggaggagctcaaaaag
accaaaggccagccttttgaccctacctttctgattggctgtgcaccctgcaatgtcatt
gcggatattctcttcaacaaacgcttcgattacgatgacaagaagtgtctggagctcatg
agtttgttcaatgaaaacttctacctgctgagtactccctggatccaggcttacaattac
ttttcggattatctacaatatctacctggaagccacagaaaagtcatgaaaaatgtgtct
gaaataagacagtacacacttggaaaagccaaggaacaccttaagtcactggacatcaac
tgcccccgggatgtgactgactgtctcctcatagagatggagaaggaaaaacacagccaa
gaacccatgtacacaatggaaaatatttctgtgactttggccgacctgttctttgcagga
acagagaccaccagcacaactctgagatatgggctcctgattctcatgaaatacccagaa
attgaagagaaacttcatgaagaaattgacagggttattgggccaagccgtgcccctgca
gtccgagacaggatgaatatgccctacatggacgctgtagtgcatgagattcagagattc
atcaacctcgtcccttccaacctgccccacgaagcaacccgagacaccgtgttccgagga
tatgtcatccccaagggtacagttgtaattccaactctggactcccttttatttgacaac
tatgagtttccagatccagagacatttaaacctgagcattttctgaatgaaaatgggaag
ttcaagtacagtgactatttcaaggcgttttctgcaggaaagcgcgtgtgtgttggagaa
ggcctggcccgcatggaactgtttctgcttttgtctgctattctgcagcattttaatctg
aagtctctggttgaccctaaggatatcgacctcagccctgttacaattggctttggcagt
atcccacgcgaatttaaactctgtgtcattcctcgttcatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (11)   
   KEGG PATHWAY (11)   
Chemical substance (44)   
   KEGG COMPOUND (44)   
Chemical reaction (22)   
   KEGG REACTION (22)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
Protein domain (2)   
   Pfam (2)   
All databases (117)   

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