KEGG   Mus musculus (mouse): 13106Help
Entry
13106             CDS       T01002                                 

Gene name
Cyp2e1, Cyp2e
Definition
cytochrome P450, family 2, subfamily e, polypeptide 1 (EC:1.14.13.n7)
Orthology
K07415  
cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
Organism
mmu  Mus musculus (mouse)
Pathway
Steroid hormone biosynthesis
Arachidonic acid metabolism
Linoleic acid metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Metabolic pathways
Non-alcoholic fatty liver disease (NAFLD)
Chemical carcinogenesis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    13106 (Cyp2e1)
   00590 Arachidonic acid metabolism
    13106 (Cyp2e1)
   00591 Linoleic acid metabolism
    13106 (Cyp2e1)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    13106 (Cyp2e1)
   00982 Drug metabolism - cytochrome P450
    13106 (Cyp2e1)
 Human Diseases
  Cancers
   05204 Chemical carcinogenesis
    13106 (Cyp2e1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    13106 (Cyp2e1)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-  
     13106 (Cyp2e1)
Cytochrome P450 [BR:mmu00199]
 Cytochrome P450, animal type
  CYP2 family
   13106 (Cyp2e1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
7 F5; 7 85.94 cM
AA seq 493 aa AA seqDB search
MAVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKL
AKRFGPVFTLHLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGP
TWKDVRRFSLSILRDWGMGKQGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVI
ADILFNKRFDYDDKKCLELMSLFNENFYLLSTPWIQAYNYFSDYLQYLPGSHRKVMKNVS
EIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQEPMYTMENISVTLADLFFAG
TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYMDAVVHEIQRF
INLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGK
FKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTIGFGS
IPREFKLCVIPRS
NT seq 1482 nt NT seq  +upstreamnt  +downstreamnt
atggcggttcttggcatcaccgttgccttgcttgtctggatcgccaccctcctcctcgta
tccatctggaaacagatctatagaagttggaacctgcccccaggacctttcccaattcct
ttctttggaaacatttttcagctggatttgaaggatattcccaagtctttaaccaagttg
gcaaagcgcttcgggccagtgttcacactgcacctgggtcagaggcgcatcgtggtcctg
catggctacaaggctgtcaaggaggtgctactgaaccacaagaatgagttctctggccga
ggggacattcctgtgttccaggagtacaagaacaaggggattattttcaataatggaccc
acatggaaggacgtgcggaggttttccctaagtatcctccgtgactggggaatggggaaa
cagggtaatgaggcccgcatccaaagagaggcacacttcctggtggaggagctcaaaaag
accaaaggccagccttttgaccctacctttctgattggctgtgcaccctgcaatgtcatt
gcggatattctcttcaacaaacgcttcgattacgatgacaagaagtgtctggagctcatg
agtttgttcaatgaaaacttctacctgctgagtactccctggatccaggcttacaattac
ttttcggattatctacaatatctacctggaagccacagaaaagtcatgaaaaatgtgtct
gaaataagacagtacacacttggaaaagccaaggaacaccttaagtcactggacatcaac
tgcccccgggatgtgactgactgtctcctcatagagatggagaaggaaaaacacagccaa
gaacccatgtacacaatggaaaatatttctgtgactttggccgacctgttctttgcagga
acagagaccaccagcacaactctgagatatgggctcctgattctcatgaaatacccagaa
attgaagagaaacttcatgaagaaattgacagggttattgggccaagccgtgcccctgca
gtccgagacaggatgaatatgccctacatggacgctgtagtgcatgagattcagagattc
atcaacctcgtcccttccaacctgccccacgaagcaacccgagacaccgtgttccgagga
tatgtcatccccaagggtacagttgtaattccaactctggactcccttttatttgacaac
tatgagtttccagatccagagacatttaaacctgagcattttctgaatgaaaatgggaag
ttcaagtacagtgactatttcaaggcgttttctgcaggaaagcgcgtgtgtgttggagaa
ggcctggcccgcatggaactgtttctgcttttgtctgctattctgcagcattttaatctg
aagtctctggttgaccctaaggatatcgacctcagccctgttacaattggctttggcagt
atcccacgcgaatttaaactctgtgtcattcctcgttcatga

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