KEGG   Mus musculus (mouse): 13666Help
Entry
13666             CDS       T01002                                 

Gene name
Eif2ak3, Pek, Perk
Definition
(RefSeq) eukaryotic translation initiation factor 2 alpha kinase 3
  KO
K08860  
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
Organism
mmu  Mus musculus (mouse)
Pathway
Mitophagy - animal
Autophagy - animal
Protein processing in endoplasmic reticulum
Apoptosis
Non-alcoholic fatty liver disease (NAFLD)
Alzheimer's disease
Hepatitis C
Measles
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    13666 (Eif2ak3)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    13666 (Eif2ak3)
   04137 Mitophagy - animal
    13666 (Eif2ak3)
  Cell growth and death
   04210 Apoptosis
    13666 (Eif2ak3)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    13666 (Eif2ak3)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    13666 (Eif2ak3)
  Infectious diseases
   05162 Measles
    13666 (Eif2ak3)
   05164 Influenza A
    13666 (Eif2ak3)
   05160 Hepatitis C
    13666 (Eif2ak3)
   05168 Herpes simplex infection
    13666 (Eif2ak3)
   05169 Epstein-Barr virus infection
    13666 (Eif2ak3)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     13666 (Eif2ak3)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: Other group
  PEK family [OT]
   13666 (Eif2ak3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Structure
PDB: 

Jmol
Position
6; 6 C1
AA seq 152 aa AA seqDB search
MERATRPGPRALLLLLFLLLGCAAGISAVAPARSLLAPASETVFGLGAAAAPTSAARVPA
VATAEVTVEDAEALPAAAGEPESRATEPDDDVELRPRGRSLVIISTLDGRIAALDAENDG
KKQWDLDVGSGSLVSSSLSKPEGTHKTSSKEC
NT seq 459 nt NT seq  +upstreamnt  +downstreamnt
atggagcgcgccacccggcccgggccgcgcgcgctgctgctgcttctgttcctgctgctg
ggctgcgcggcggggatctcggcggtcgcgcccgcccgcagtttgcttgctcccgcgtcg
gagacagtgtttggcttaggggcagcggccgccccgacttcggccgcgcgggtgcctgcg
gtggcaacggccgaagtgaccgtggaggacgccgaggcattgccggctgccgctggcgaa
ccggagtcacgcgcgacggagcccgatgacgacgtggaactgcggcctcgcggcaggtcc
ttggtaatcatcagcactttagatggacgaatcgctgcactggatgccgagaatgatggg
aaaaagcagtgggatttggacgtggggtctggttccttggtttcatctagcctcagcaag
ccagagggcacccacaaaacttcctcaaaagaatgttga

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