KEGG   Mus musculus (mouse): 14370Help
Entry
14370             CDS       T01002                                 

Gene name
Fzd8, Fz8
Definition
(RefSeq) frizzled class receptor 8
  KO
K02375  
frizzled 5/8
Organism
mmu  Mus musculus (mouse)
Pathway
mTOR signaling pathway
Wnt signaling pathway
Hippo signaling pathway
Signaling pathways regulating pluripotency of stem cells
Melanogenesis
HTLV-I infection
Pathways in cancer
Proteoglycans in cancer
Basal cell carcinoma
Breast cancer
Module
Wnt signaling
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    14370 (Fzd8)
   04390 Hippo signaling pathway
    14370 (Fzd8)
   04150 mTOR signaling pathway
    14370 (Fzd8)
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    14370 (Fzd8)
 Organismal Systems
  Endocrine system
   04916 Melanogenesis
    14370 (Fzd8)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    14370 (Fzd8)
   05205 Proteoglycans in cancer
    14370 (Fzd8)
   05217 Basal cell carcinoma
    14370 (Fzd8)
   05224 Breast cancer
    14370 (Fzd8)
  Infectious diseases
   05166 HTLV-I infection
    14370 (Fzd8)
G protein-coupled receptors [BR:mmu04030]
 Others
  Wnt signaling
   Frizzled / Smoothened family
    14370 (Fzd8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Structure
PDB: 

Jmol
Position
18 A1; 18 4.91 cM
AA seq 685 aa AA seqDB search
MEWGYLLEVTSLLAALAVLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHD
TQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAP
LMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPPGEQPPSG
SGHSRPPGARPPHRGGSSRGSGDAAAAPPSRGGKARPPGGGAAPCEPGCQCRAPMVSVSS
ERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLIDM
ERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAAGAGA
AGAGASSPGARGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWF
LAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLR
GFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQGGPTKTHKLEKLMIRLGLFTVLYTV
PAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITSGV
WVWSGKTLESWRALCTRCCWASKGAAVGAGAGGSGPGGSGPGPGGGGGHGGGGGSLYSDV
STGLTWRSGTASSVSYPKQMPLSQV
NT seq 2058 nt NT seq  +upstreamnt  +downstreamnt
atggagtggggttacctgttggaagtgacctcgctcctagccgccttggcggtgctacag
cgctctagcggcgctgccgcggcttcggccaaggagctggcgtgccaagagatcacggtg
ccgttgtgcaaaggcatcggttacaactacacttacatgcccaaccagttcaaccacgac
acgcaagatgaggcgggcctagaggtgcaccagttttggccgctggtggagatacagtgc
tccccggacctcaagttctttctgtgtagcatgtacacgcccatctgcctggaggactac
aagaagcctctgccgccttgtcgctctgtgtgtgaacgcgccaaggccggctgcgcgccg
ctcatgcgccagtacggctttgcttggcctgaccgcatgcgctgcgatcggttgccggag
cagggcaacccggacactctgtgcatggactacaaccgcaccgacctcaccacggccgcg
cccagcccaccgcgccgcctgcctccgccgcctcctcccggcgagcagccgccctctggc
agcggccacagccgcccgccaggggccaggcccccacatcgtggcggcagcagtaggggc
agcggggacgcggcggctgcgcccccttcgcgcggcgggaaggcgaggccccctggtggc
ggcgctgctccctgcgagccggggtgccagtgccgcgcgcccatggtgagcgtgtccagc
gaacgccacccgctctacaaccgcgtcaagaccggccagatcgccaactgtgcgctgccc
tgccacaaccccttctttagccaggatgagcgcgccttcaccgtcttctggatcggcctg
tggtcggtgctctgcttcgtctccaccttcgccactgtctctaccttcctcatcgatatg
gagcgctttaagtacccggaacggcccatcatattcctctccgcctgttacctcttcgtg
tctgtcgggtacctggtgcgcctggtggcaggacatgagaaagtggcctgcagcggcggc
gctccgggtgctggcggagctgggggtgcgggcggcgcggcggcggctggcgcaggggca
gcgggagcgggggcgagcagcccgggcgcgcgcggcgagtacgaggagctgggtgcagtc
gagcagcatgttcgctatgaaaccactggccccgcgctgtgcacggtggtctttctcctt
gtctacttttttggcatggccagctccatctggtgggtaatcctgtcgctcacgtggttc
ttggcagctggcatgaagtggggtaatgaggccatagcaggctactcgcagtacttccac
ctggccgcgtggcttgtgcccagcgtcaagtccatcgcggtgctggcgctcagctccgta
gacggcgacccggtggcgggcatctgctacgtgggcaaccagagccttgacaacctacgc
ggctttgtgctggcgccactggttatctacctcttcattgggactatgtttctgttagct
ggcttcgtgtcgctgttccgaatccgttcagtcatcaagcagcaaggaggcccaactaag
acacacaagctagaaaaactcatgatccgcttgggcctcttcaccgtgctctacacggtg
cccgctgccgtcgttgtcgcctgccttttctatgagcagcacaaccgaccgcgctgggag
gccacgcacaactgcccatgccttcgggacctgcaaccggaccaggctcgcaggcccgat
tacgcggtcttcatgctcaagtacttcatgtgcctagtagtgggcatcacatcgggcgtg
tgggtctggtccggcaagactctggagtcctggcgcgcgttgtgcactaggtgctgctgg
gccagcaagggcgctgcagtaggcgcgggcgctggaggcagcggccctgggggcagtgga
cccgggcccggcggaggtgggggacacggcggaggcgggggatccctctacagcgacgtc
agtaccggcctgacgtggcggtctggcacggccagctctgtatcttaccctaagcaaatg
ccattgtcccaggtctga

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