KEGG   Mus musculus (mouse): 16402Help
Entry
16402             CDS       T01002                                 

Gene name
Itga5, Cd49e, Fnra, VLA5
Definition
(RefSeq) integrin alpha 5 (fibronectin receptor alpha)
  KO
K06484  
integrin alpha 5
Organism
mmu  Mus musculus (mouse)
Pathway
Phagosome
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Hematopoietic cell lineage
Regulation of actin cytoskeleton
Bacterial invasion of epithelial cells
Pertussis
Proteoglycans in cancer
MicroRNAs in cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    16402 (Itga5)
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    16402 (Itga5)
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    16402 (Itga5)
  Cell motility
   04810 Regulation of actin cytoskeleton
    16402 (Itga5)
  Cellular commiunity
   04510 Focal adhesion
    16402 (Itga5)
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    16402 (Itga5)
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    16402 (Itga5)
   05205 Proteoglycans in cancer
    16402 (Itga5)
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    16402 (Itga5)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    16402 (Itga5)
   05414 Dilated cardiomyopathy (DCM)
    16402 (Itga5)
  Infectious diseases
   05133 Pertussis
    16402 (Itga5)
   05100 Bacterial invasion of epithelial cells
    16402 (Itga5)
Exosome [BR:mmu04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   16402 (Itga5)
Cell adhesion molecules and their ligands [BR:mmu04516]
 1. Immunoglobulin Superfamily
  Neural system
   6/5 subfamily
    L1CAM; L1 cell adhesion molecule [KO:K06550]
     VLA-5 Cell adhesion molecules (CAMs)
      16402 (Itga5)
 5. Cadherin Family
  Clustered protocadherin
   PCDHA; protocadherin alpha [KO:K16493]
    VLA-5 Cell adhesion molecules (CAMs)
     16402 (Itga5)
 7. Others
  TNFSF5, CD40L; tumor necrosis factor (ligand) superfamily, member 5 [KO:K03161]
   VLA-5 Cell adhesion molecules (CAMs)
    16402 (Itga5)
  SDC1; syndecan 1 [KO:K06257]
    16402 (Itga5)
  SDC4; syndecan 4 [KO:K16338]
    16402 (Itga5)
Cellular antigens [BR:mmu04090]
 Proteins
  16402 (Itga5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
15 F3; 15 58.9 cM
AA seq 725 aa AA seqDB search
MASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQRPAGIDPTPTL
TLTGQDEFSRFGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGVVFIFPGGPGGLSTKPSQ
VLQPLWAAGRTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKALVYRGRPIISASASLTI
FPSMFNPEERSCSLEGNPVSCINLSFCLNASGKHVPNSIGFEVELQLDWQKQKGGVRRAL
FLTSKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPKAPMDSH
GLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLDVYGEKKHVYLGDKNALNLTFHAQ
NLGEGGAYEAELRVTAPLEAEYSGLVRHPGNFSSLSCDYFAVNQSRQLVCDLGNPMKLWG
GLRFTVPHLQDTKKTIQFDFQILSKNLNNSQSNVVSFPLSVEAQAQVSLNGVSKPEAVIF
PVSDWNPQDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALEGQQLLYVTKVT
GLSNCTSNYTPNSQGLELDPETSPHHLQKREAPGRSSTASGTQVLKCPEAKCFRLRCEFG
PLHRQESRSLQLHFRVWAKTFLQREYQPFSLQCEAVYEALKMPYQILPRQLPQKKLQVAT
AVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKLGFFKRSLPYGTAMEKAQLKPP
ATSDA
NT seq 2178 nt NT seq  +upstreamnt  +downstreamnt
atggcctcctacttcggctatgctgtggctgccactgataccaatggagatgggctagat
gacctactggtaggggcacccctgctcatggagcggacagctgatgggagacctcaggag
gtgggcagggtctacatctatctgcagcgcccagcgggcatagatcccacacccaccctc
accctcactgggcaagatgagttcagccgattcggcagctccttgacacccttgggggac
ctggaccaagacggctacaatgatgtcgccattggggctccatttggtggggaggcccag
cagggagtcgtatttatattcccgggaggcccaggaggactgagcactaaaccttcccag
gttttgcagcctctttgggcagctggccgtaccccagacttctttggctctgcccttcga
ggaggacgagatctggatggcaatggataccctgatctaatcgttggatcctttggtgtg
gacaaggctctggtgtacagagggcggcccatcatatctgccagcgcatctctcaccatc
ttcccctccatgttcaacccagaggagcgcagttgcagcctggaagggaaccctgtgtcc
tgcatcaaccttagcttctgcctcaatgcctctggaaaacatgtccccaactctataggc
ttcgaggtggaactccaactggactggcagaagcaaaagggaggggtccggcgggcactg
ttcctgacttccaagcaggccacccttacccagaccctgcttatccagaatggggctcgg
gaggactgcagggagatgaagatctacctcaggaatgaatcagaattcagagacaaactc
tccccaattcacattgccctcaacttctccttggaccccaaagctcccatggacagccat
ggcctccggccagttctacactaccaaagcaaaagcaggatagaggacaaggcccagatc
ttgctggactgtggtgaagacaatatctgtgtgcctgacctgcagctggatgtgtatggg
gagaagaaacatgtgtacctgggtgacaagaacgcactgaacctgacattccatgcccaa
aatctgggtgagggcggtgcctatgaagccgagcttcgggtcacagcccctctagaggcc
gagtactcaggacttgtcagacacccagggaacttctccagcctgagctgtgactacttt
gctgtgaaccagagccgccagctggtgtgtgacctgggcaaccccatgaagctctggggt
ggccttcggttcactgttcctcatcttcaagacacaaagaaaaccatccagtttgacttt
cagatcctcagcaagaacctgaacaactcacaaagcaacgtggtctccttcccactctcg
gtggaggctcaagcccaggtctcccttaatggtgtctccaagcctgaagctgtgattttc
ccagtcagcgactggaatcctcaagaccagcctcagaaggaggaagacttgggcccagct
gtccaccatgtctacgagctcatcaaccaggggcccagctccatcagccagggtgtgctg
gagctcagctgtccacaggctctggaaggccaacagctcctctatgtgaccaaggtgaca
ggactcagcaactgcacctccaactacacccccaactcacagggcctggagttggatcca
gagacctctccacaccacctgcagaaacgagaggctccagggaggagttctactgcctca
ggaacacaagttctgaaatgccctgaagccaagtgtttcaggctgcgctgtgagtttggg
ccactgcaccgccaagagagccgtagtctgcagctgcatttccgagtctgggccaagacc
ttcttgcagcgggaataccagccatttagccttcagtgtgaggctgtatatgaagctctg
aagatgccctaccagatcctgcctcggcagcttccccaaaagaaacttcaggtggccaca
gccgtgcagtggaccaaggcagaaggcagcaatggtgtcccgttgtggatcatcatccta
gccattctttttggcctcctgctcctaggtctgctcatctacgtcctctacaagctcggc
ttcttcaaacgttccctcccctacggcacagccatggaaaaagctcagctcaagcctcca
gccacctcagatgcctga

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