KEGG   Mus musculus (mouse): 16801Help
Entry
16801             CDS       T01002                                 

Gene name
Arhgef1, Lbcl2, Lsc
Definition
Rho guanine nucleotide exchange factor (GEF) 1
Orthology
K12330  
Rho guanine nucleotide exchange factor 1
Organism
mmu  Mus musculus (mouse)
Pathway
Vascular smooth muscle contraction
Platelet activation
Regulation of actin cytoskeleton
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    16801 (Arhgef1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    16801 (Arhgef1)
  Circulatory system
   04270 Vascular smooth muscle contraction
    16801 (Arhgef1)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    16801 (Arhgef1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
7 A3; 7
AA seq 979 aa AA seqDB search
MGEVAGGAAPGPPRSGLVSIIIGAEDEDFENELEANSEDQNSQFQSLEQVKRRPAHLMAL
LQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPSVAFEL
DRTRPDLISEDVQRRFIQEVVQSQQAAVSRQLEDFRSKRLMGMTPWEQELSLLEPWIGKD
RGNYEARERHVAERLLSHLEETQHTISTDEEKSAAVVTAISLYMRHLGVRTKSGDKKSGR
NFFRKKVMGNRRSDEPPKTKKGLSSILDPARWNRGEPSAPDCRHLKVEADEKPGPADRKG
GLGMSSRDRTVGTPGQDNPGVSLHPLSTDSVDSREPGVDTPQEPGDTPPQGPTSLEPLAP
PESTEDNGETERRWKRLSGRLGRSESLRVSDRRRPSRGSLGAKGRGGGRSRSDVDMDPGS
ATAVLGPTRRATPEPGDDGEPGRSGLELEPEEPPGWRELVPPDTLLSLPKSQVKRQEVIS
ELLVTEAAHVRMLRVLHDLFYQPMADGGFFPLDELQNIFPSLDELIEVHSLFLDRLMKRR
QESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQE
AESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEESTERGKVELAAECCREILHHV
NQAVRDMEDLLRLKDYQRRLDLTHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDK
AIEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATDH
KAFYVIFTWDQEAQIYELVAQTSSERKNWCNLITETAGSLKVPAPASRLKPRPSPSSIRE
PLLSSSENGTGGAEMAPADARTERLLNDLLPFCRPGPEGQLAATALQKVLSLKQILLSTE
EDSGAGPPRDGDGVPGGRAPGPVHTQEIEENLLSLEVAIRQLEELEEEFCRLRPLLSQLG
GTLSPNLAAPERSAQTGLS
NT seq 2940 nt NT seq  +upstreamnt  +downstreamnt
atgggagaagtcgccggaggggcggccccagggcctccccggtctggcctggtgtccatc
atcatcggggcggaggatgaggattttgagaacgagctggaggcgaactcagaagatcaa
aacagccagttccagagcctagagcaagtgaagcgccgccctgcccacctcatggccctc
ctgcagcatgtggccctgcagttcgagccaggaccactgctctgctgcctgcatgcagac
atgctgagctctctgggccccaaagaagccaagaaggccttccttgacttctatcacagt
ttcctggagaagactgcggttctacgggtgccggtccctcccagtgtcgcttttgaactt
gatcgtactcgacctgatctgatctctgaggatgtccagaggcggttcatacaagaggtg
gtgcagagccagcaggcagccgtgagccgtcagctagaggacttccgctccaagcggctc
atgggcatgacgccctgggagcaggaactgagcctgctggagccctggattgggaaagac
cgaggcaactatgaggcccgggagcggcatgttgcggagcggctgctgtcccacctggag
gagacccagcataccatctctacagatgaagagaaaagtgctgctgtggtcactgccatc
agcctgtatatgcgccaccttggagtccggaccaagagtggggacaagaagtcgggaagg
aacttcttccggaaaaaggtgatggggaatcggaggtcagacgaacccccaaagacaaag
aaagggctgagcagtatcctagatcctgcacgttggaaccggggagagccatccgctcca
gattgtcgacatctaaaggtcgaggctgatgagaagccaggccctgcagaccggaaggga
ggcctgggtatgtcttctcgggacaggactgttgggactcctggacaggacaacccagga
gtctccctgcaccctctgtctacagacagcgtcgactcccgggaaccaggcgtggatacc
ccgcaggagccaggggatacacccccacagggccctaccagcctggagcccctggcgccc
ccagagagcacagaggacaatggcgagactgagagaaggtggaagaggctatcagggcgt
ctagggcgctcagagagcctgcgggtgagtgaccgccgccggccttcccggggcagcctc
ggggctaagggccggggtgggggccgttcccggagcgacgtggacatggacccgggctcc
gccacggccgtgcttggccccacccgacgagccacccctgagcccggagatgatggggag
ccaggacggtcaggcctggaactggaaccagaagaacctcctgggtggagggaactcgtg
cccccagacaccctgctcagtctgcccaagagccaagtgaagcggcaagaggtcatcagc
gagctgctcgtgactgaggcagctcacgtgcgcatgctacgggtactgcatgacctcttc
taccagcccatggcggatggaggcttcttccctctggacgagctgcagaacatcttcccg
agcctggatgagctcatcgaggtgcactccctgttcctcgatcgcttgatgaagcggaga
caagagagtggctacctcattgaggagatcggcgatgtgctactggcccggttcgatggt
gctgagggctcatggttccagaagatctcctcccgcttctgcagccgccagtcgttcgct
ctagagcagctcaaagccaagcagcgcaaggagcctcggttctgtgcctttgtgcaggaa
gctgagagccgcccgagatgccggcgcctacagttaaaggacatgatccccactgagatg
cagcgactgaccaagtacccactgctgctacagagcatcgggcagaacacagaggagtct
acagaacgagggaaagtggagcttgcagctgagtgctgccgggagattctgcaccatgtc
aatcaagccgtccgtgacatggaggacctgctgcggctcaaggattaccagcggcgcctg
gacttgactcacctacggcagagcagtgaccctatgctgagcgagttcaagaacctggac
atcactaagaagaagttggtccatgaaggccccctcacgtggcgagtgaccaaagacaaa
gctatagaagtgcacgtgctcttgctggacgacctgctgctgctgctccagcgccaggac
gagaggctgctgctcaagtcccacagccggacgctgacacctacccccgatggcaagacc
atgctgcggccggtgctccggctcacctctgccatgacccgagaggtggccactgatcac
aaagctttctacgtcatttttacctgggaccaggaggcccagatatatgagctggtggca
cagacatcttcggaacgcaaaaactggtgtaacctcatcactgagactgctggatccctg
aaggtccctgcccctgcctcccgcctcaaaccccggcccagcccaagcagcatccgagaa
cccctgctcagcagctctgagaatggcactggaggcgcagagatggctccagctgatgcc
aggacagagcggctcctcaatgacctcctgcccttctgcagaccaggcccagagggccag
cttgctgccacagcccttcagaaagtactgtccctgaagcagatcctgctaagcactgag
gaagacagtggagcggggcctccccgcgatggggatggggtgcctggtggtagggccccc
ggcccagtgcacacccaggagattgaggaaaacttgcttagcttagaggtggccatcaga
caactggaggagttggaagaggaattttgtcgcctaagacccctcctgtcccagcttggg
gggactctgtcccccaacctggctgcacctgaacgctctgctcagacaggcctttcatga

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