KEGG   Mus musculus (mouse): 18641Help
Entry
18641             CDS       T01002                                 

Gene name
Pfkl, AA407869, ATP-PFK, PFK-L
Definition
phosphofructokinase, liver, B-type (EC:2.7.1.11)
Orthology
K00850  
6-phosphofructokinase 1 [EC:2.7.1.11]
Organism
mmu  Mus musculus (mouse)
Pathway
Glycolysis / Gluconeogenesis
Pentose phosphate pathway
Fructose and mannose metabolism
Galactose metabolism
Metabolic pathways
Carbon metabolism
Biosynthesis of amino acids
RNA degradation
HIF-1 signaling pathway
AMPK signaling pathway
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    18641 (Pfkl)
   01230 Biosynthesis of amino acids
    18641 (Pfkl)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    18641 (Pfkl)
   00030 Pentose phosphate pathway
    18641 (Pfkl)
   00051 Fructose and mannose metabolism
    18641 (Pfkl)
   00052 Galactose metabolism
    18641 (Pfkl)
 Genetic Information Processing
  Folding, sorting and degradation
   03018 RNA degradation
    18641 (Pfkl)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    18641 (Pfkl)
   04152 AMPK signaling pathway
    18641 (Pfkl)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    18641 (Pfkl)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.11  6-phosphofructokinase
     18641 (Pfkl)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     18641 (Pfkl)
Messenger RNA biogenesis [BR:mmu03019]
 Prokaryotic Type
  Bacterial mRNA degradation factors
   RNA degradosome components
    Other RNA degradosome components
     18641 (Pfkl)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
10 C1; 10 39.72 cM
AA seq 780 aa AA seqDB search
MATVDLEKLRMSGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVE
GGENIKPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDG
SLTGANIFRNEWGSLLEELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDS
ALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWE
NFMCERLGETRSRGSRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQ
RGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQK
AMDEERFDEAIQLRGRSFENNWKIYKLLAHQKVSKEKSNFSLAILNVGAPAAGMNAAVRS
AVRTGISEGHTVYIVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKPHLEAI
VENLRTYNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLG
SDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFN
IHDLKANVEHMTEKMKTDIQRGLVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGH
LQQGGAPTPFDRNYGTKLGVKAMLWVSEKLRDVYRKGRVFANAPDSACVIGLRKKVVAFS
PVTELKKETDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIDKGF
NT seq 2343 nt NT seq  +upstreamnt  +downstreamnt
atggctaccgtggacctggagaaactgcggatgtcgggggctggcaaggccattggagtg
ctgaccagcggcggtgatgcgcaaggtatgaatgctgctgtcagggctgtgacccgtatg
ggcatatatgtgggggccaaagtcttcctcatctatgagggctacgagggccttgtggaa
ggaggcgagaacatcaagccagccaactggctcagcgtttccaatatcatccagctgggt
ggcaccattattggcagtgcccgctgtaaggccttcactacgagggaaggccgcctggct
gcagcctacaatctgctccaacacggcatcaccaacctgtgtgtcatcggtggcgacggc
agcctcacgggggccaacatcttccgcaacgagtggggcagcttgctggaggagctggtg
aaggaaggcaagatctcagagtccacagctcagaactacgcacacttgaccatcgccggt
ctggtgggctccatcgataacgacttctgtggcactgacatgaccattggcacagactca
gccctgcaccgcattatggaggtcattgacgccatcactaccactgcccaaagtcaccag
aggacctttgttttggaggtgatgggacggcactgcgggtacctggcgctggtgtctgcc
ctggcttccggggctgattggctattcattcctgaagcgccccctgaggatggctgggag
aacttcatgtgtgagaggctgggcgagactcggagccgaggctctcggctgaacatcatc
atcatcgcagagggtgccattgaccggcatggaaagcctatctcatccagctacgtgaag
gatctggtggttcagaggctgggcttcgatacacgagtgactgtgctgggtcatgtacag
cgaggagggacgccttcagccttcgaccgaatcctgagtagcaagatgggtatggaggcc
gtgatggcgctgctagaggccacgcctgacacgccggcctgtgtggtcagcctctccggg
aaccagtctgtgaggctacctctcatggagtgtgtgcaagtgacaaaggacgtgcagaag
gccatggacgaggagaggtttgacgaggccatccagctccgtggcaggagctttgagaac
aactggaaaatttacaagctccttgcccaccagaaggtgtctaaagagaagtccaacttc
tccctggccatcctgaatgtgggggctccagctgctggcatgaatgcagctgtgcgctcc
gcagtgcgcactggtatctccgagggacacacggtatacatcgtgcatgatggctttgag
ggtctggccaagggtcaggtgcaagaagtgggctggcatgatgtggcaggctggctggga
cgtggtggctcgatgctggggaccaagaggacactgcccaagccccacctggaggccatt
gtggagaatctccgcacctacaacatccacgccctgctggtgattggtggctttgaggcc
tacgagggtgtgctgcagctggtggaggcccgggggcgctacgaggaactctgcattgtc
atgtgtgtcatcccagccaccatcagcaacaatgtgcctggcactgacttcagcctgggc
tcagacacggctgtcaacgctgcaatggagagttgtgatcgcatcaagcagtcagcctca
gggacaaagcggcgtgtgttcattgtagagaccatggggggctactgtggctacctggct
actgtgaccggcattgctgtgggtgccgatgctgcctacgtctttgaggaccctttcaac
atccatgacttaaaggccaatgtggagcatatgacagagaagatgaagacagacatccag
aggggactggtgctccggaacgagaagtgtcacgaacactacaccacagagttcctatac
aacctgtactcctcagaaggcaggggcgtgtttgactgcaggaccaatgtgctgggccac
ttgcagcagggtggtgctccaacccctttcgaccggaactatgggaccaaactgggggtg
aaggccatgttgtgggtgtctgagaagctacgtgatgtctaccgtaaagggcgggtgttt
gccaatgctccagactcagcctgtgtgatcggcctgcggaagaaggtagtggccttcagt
ccggtcacagaactcaagaaagagactgattttgagcaccgcatgccccgggagcagtgg
tggctgaatctgcggctgatgctgaagatgctggcacactaccgcatcagcatggcagac
tatgtgtctggggagctggagcacgtcacacgccgcaccttgagcatagacaagggtttc
tga

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