KEGG   Mus musculus (house mouse): 18719
Entry
18719             CDS       T01002                                 
Symbol
Pip5k1b, PI4P5K-I[b], PIP5K1-beta, PIP5KIbeta, Pipk5b, STM7
Name
(RefSeq) phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
  KO
K00889  1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00562  Inositol phosphate metabolism
mmu01100  Metabolic pathways
mmu04070  Phosphatidylinositol signaling system
mmu04072  Phospholipase D signaling pathway
mmu04144  Endocytosis
mmu04510  Focal adhesion
mmu04666  Fc gamma R-mediated phagocytosis
mmu04810  Regulation of actin cytoskeleton
mmu05135  Yersinia infection
mmu05231  Choline metabolism in cancer
Module
mmu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    18719 (Pip5k1b)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    18719 (Pip5k1b)
   04072 Phospholipase D signaling pathway
    18719 (Pip5k1b)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    18719 (Pip5k1b)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    18719 (Pip5k1b)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    18719 (Pip5k1b)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    18719 (Pip5k1b)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    18719 (Pip5k1b)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    18719 (Pip5k1b)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    18719 (Pip5k1b)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.68  1-phosphatidylinositol-4-phosphate 5-kinase
     18719 (Pip5k1b)
Membrane trafficking [BR:mmu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    18719 (Pip5k1b)
 Endocytosis
  Clathrin-mediated endocytosis
   LDLR adaptor proteins
    18719 (Pip5k1b)
 Endosome - Golgi transport
  Others
   Others
    18719 (Pip5k1b)
SSDB
Motif
Pfam: PIP5K
Other DBs
NCBI-GeneID: 18719
NCBI-ProteinID: NP_032872
MGI: 107930
Ensembl: ENSMUSG00000024867
UniProt: P70181
Position
19:complement(24272158..24533236)
AA seq 539 aa
MSSTAENGDAVPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVV
ESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNP
GASGSLFFLTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG
INIRIVVMNNVLPRAMRMHLTYDLKGSTYKRRASRKEREKPNPTFKDLDFLQDMHEGLYF
DTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHILDHSLKDKEEEPLQNVPDAKRPGMQ
KVLYSTAMESIQGPGKSADGIIAENPDTMGGIPAKSHKGEKLLLFMGIIDILQSYRLMKK
LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKAT
SQEIVSSISQEWKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPSTPSLFEAASLATTIS
SSSLYVGEHYPHDRTTLYSNSKGLPSSSTFTLEEGTIYLTAEPNTLDLQDDASVLDVYL
NT seq 1620 nt   +upstreamnt  +downstreamnt
atgtcgtcaactgctgaaaatggagacgccgtacctggaaaacaaaacgaagaaaaaacc
tacaaaaagacggcatcgtcagctattaaaggtgctatccagctgggaataggatacaca
gtgggcaacctcacgtccaagccagaacgcgatgtcctcatgcaagacttctacgtggtg
gaaagtgtgttcctccccagtgaagggagcaacctgaccccagcacatcactacccagac
ttcaggtttaagacctacgcaccgctggccttccggtacttccgagaactctttggtatc
aagcccgatgattacttgtactccatctgcagtgaacctctgatagaactgtccaatcct
ggagccagtgggtccttgtttttcttgaccagcgatgatgaatttatcatcaaaaccgtt
cagcataaggaagccgagttcctgcagaagctgctgccgggctattacatgaatttaaac
cagaatccaaggactcttctgccaaaattctatgggctgtattgcatgcagtcaggaggc
atcaacatccgcattgtggtgatgaacaatgtcctgccgcgtgccatgaggatgcatttg
acctatgacctgaaaggctccacatacaagcgaagagcatcccgaaaagagagggagaaa
cccaaccccacgtttaaggacctggacttcctgcaggacatgcacgaggggctgtatttc
gatacagaaacatacaatgcccttatgaagacactacagagagactgccgggttctggaa
agcttcaagatcatggactacagccttttgctgggtatccacatcttggaccattccctc
aaagacaaagaagaggagcccctccaaaacgtgcctgatgcaaagcggccggggatgcag
aaagtcctctattccacagccatggaatccatccagggtccaggcaagtctgcagatggg
atcattgcagagaatccagacacaatgggaggcattccagctaaaagccataagggagag
aagctgcttctattcatgggcattattgacatcctccaatcatataggttaatgaagaag
ttagaacattcctggaaagcccttgtttatgatggggacaccgtttcagttcatagacca
agtttttatgcagatagatttttaaagtttatgaattccagagttttcaagaaaattcaa
gctctgaaagcctcgccttctaagaaacgctgcaactccatcgctgcactgaaggcaacc
tcccaggagatcgtatcctccatcagccaggaatggaaggacgagaagcgggatttgtta
accgaaggacagagtttcagcagcctggatgaagaagccctgggatcccgacacaggccc
gacctggtacccagcactccatcattatttgaagctgcttccttagcgaccacaatatca
tcttcttccttatatgtcggcgaacactatccacatgacaggactaccctttactcaaac
agcaaagggttaccttccagttcaaccttcaccttggaagaggggaccatctacctgacg
gctgagccaaacaccctggacctgcaggatgatgcctctgtgctggacgtctatttataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (20)   
   RefSeq(nuc) (2)   
   GenBank (9)   
   EMBL (9)   
Protein domain (1)   
   Pfam (1)   
All databases (60)   

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