KEGG   Mus musculus (mouse): 18749Help
Entry
18749             CDS       T01002                                 

Gene name
Prkacb, Pkacb
Definition
protein kinase, cAMP dependent, catalytic, beta (EC:2.7.11.11)
Orthology
K04345  
protein kinase A [EC:2.7.11.11]
Organism
mmu  Mus musculus (mouse)
Pathway
MAPK signaling pathway
Ras signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Apoptosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Hedgehog signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
GABAergic synapse
Dopaminergic synapse
Olfactory transduction
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Vasopressin-regulated water reabsorption
Salivary secretion
Gastric acid secretion
Bile secretion
Parkinson's disease
Prion diseases
Cocaine addiction
Amphetamine addiction
Morphine addiction
Amoebiasis
HTLV-I infection
Epstein-Barr virus infection
Viral carcinogenesis
Proteoglycans in cancer
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    18749 (Prkacb)
   04010 MAPK signaling pathway
    18749 (Prkacb)
   04310 Wnt signaling pathway
    18749 (Prkacb)
   04340 Hedgehog signaling pathway
    18749 (Prkacb)
   04020 Calcium signaling pathway
    18749 (Prkacb)
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    18749 (Prkacb)
   04210 Apoptosis
    18749 (Prkacb)
  Cell communication
   04540 Gap junction
    18749 (Prkacb)
 Organismal Systems
  Immune system
   04611 Platelet activation
    18749 (Prkacb)
   04062 Chemokine signaling pathway
    18749 (Prkacb)
  Endocrine system
   04911 Insulin secretion
    18749 (Prkacb)
   04910 Insulin signaling pathway
    18749 (Prkacb)
   04912 GnRH signaling pathway
    18749 (Prkacb)
   04913 Ovarian Steroidogenesis
    18749 (Prkacb)
   04915 Estrogen signaling pathway
    18749 (Prkacb)
   04914 Progesterone-mediated oocyte maturation
    18749 (Prkacb)
   04921 Oxytocin signaling pathway
    18749 (Prkacb)
   04918 Thyroid hormone synthesis
    18749 (Prkacb)
   04919 Thyroid hormone signaling pathway
    18749 (Prkacb)
   04916 Melanogenesis
    18749 (Prkacb)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    18749 (Prkacb)
   04270 Vascular smooth muscle contraction
    18749 (Prkacb)
  Digestive system
   04970 Salivary secretion
    18749 (Prkacb)
   04971 Gastric acid secretion
    18749 (Prkacb)
   04976 Bile secretion
    18749 (Prkacb)
  Excretory system
   04962 Vasopressin-regulated water reabsorption
    18749 (Prkacb)
   04961 Endocrine and other factor-regulated calcium reabsorption
    18749 (Prkacb)
  Nervous system
   04724 Glutamatergic synapse
    18749 (Prkacb)
   04727 GABAergic synapse
    18749 (Prkacb)
   04725 Cholinergic synapse
    18749 (Prkacb)
   04728 Dopaminergic synapse
    18749 (Prkacb)
   04726 Serotonergic synapse
    18749 (Prkacb)
   04720 Long-term potentiation
    18749 (Prkacb)
   04723 Retrograde endocannabinoid signaling
    18749 (Prkacb)
  Sensory system
   04740 Olfactory transduction
    18749 (Prkacb)
   04742 Taste transduction
    18749 (Prkacb)
   04750 Inflammatory mediator regulation of TRP channels
    18749 (Prkacb)
  Environmental adaptation
   04713 Circadian entrainment
    18749 (Prkacb)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    18749 (Prkacb)
   05203 Viral carcinogenesis
    18749 (Prkacb)
  Neurodegenerative diseases
   05012 Parkinson's disease
    18749 (Prkacb)
   05020 Prion diseases
    18749 (Prkacb)
  Substance dependence
   05030 Cocaine addiction
    18749 (Prkacb)
   05031 Amphetamine addiction
    18749 (Prkacb)
   05032 Morphine addiction
    18749 (Prkacb)
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    18749 (Prkacb)
  Infectious diseases
   05166 HTLV-I infection
    18749 (Prkacb)
   05169 Epstein-Barr virus infection
    18749 (Prkacb)
   05146 Amoebiasis
    18749 (Prkacb)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     18749 (Prkacb)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: AGC group
  PKA family
   18749 (Prkacb)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
3; 3 H3
AA seq 338 aa AA seqDB search
MNVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMK
ILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHL
RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK
GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS
GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEA
PFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF
NT seq 1017 nt NT seq  +upstreamnt  +downstreamnt
atgaatgtgaaagagtttctagccaaagccaaagaagactttctgaggaaatgggagaac
cctcccccgagtaatgctgggcttgaggattttgagaggaagaaaaccctcgggacgggt
tcctttggaagagtcatgttggtgaagcataaagccactgagcagtactacgccatgaag
atcttagacaagcagaaggttgttaagctgaagcaaatagagcacactctgaatgagaag
agaatcctgcaggccgtggagttcccgttccttgtgcggctggagtactcttttaaggat
aattctaatttatacatggttatggaatacgtccctgggggagagatgttctcacatctg
agaagaattggaaggttcagtgagccccacgcccgtttctatgcagcccagattgtgcta
acatttgagtaccttcattccctcgacctcatctacagagatctcaagccggaaaacctc
ttaattgaccaccagggttacatccaggtcacagatttcgggttcgccaaaagagtcaag
ggcaggacatggacattgtgtggcaccccagagtacctggccccggagatcatcctcagc
aagggttacaataaggcggtggactggtgggcactgggcgtgctgatctatgagatggct
gctggctaccctccattctttgctgaccagccaattcagatctatgagaagattgtctct
ggaaaggtccggttcccatcacacttcagctccgatctcaaggaccttctgcggaacctg
ctgcaggtggatctgacaaagcgattcgggaacctgaagaacggcgtgagtgacataaag
acccacaagtggtttgccacaactgactggattgctatttatcagagaaaggttgaggct
ccattcataccaaagttcagaggctctggcgataccagcaacttcgatgactatgaagaa
gaagaaatccgtgtgtctataacagaaaaatgtggaaaggaattttgtgaattttag

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