KEGG   Mus musculus (mouse): 19045Help
Entry
19045             CDS       T01002                                 

Gene name
Ppp1ca, Ppp1c, dism2
Definition
protein phosphatase 1, catalytic subunit, alpha isoform (EC:3.1.3.16)
Orthology
K06269  
serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
mmu  Mus musculus (mouse)
Pathway
mRNA surveillance pathway
cGMP-PKG signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Hippo signaling pathway
Focal adhesion
Platelet activation
Long-term potentiation
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Oxytocin signaling pathway
Amphetamine addiction
Alcoholism
Herpes simplex infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Genetic Information Processing
  Translation
   03015 mRNA surveillance pathway
    19045 (Ppp1ca)
 Environmental Information Processing
  Signal transduction
   04390 Hippo signaling pathway
    19045 (Ppp1ca)
   04022 cGMP - PKG signaling pathway
    19045 (Ppp1ca)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    19045 (Ppp1ca)
  Cell growth and death
   04114 Oocyte meiosis
    19045 (Ppp1ca)
  Cell communication
   04510 Focal adhesion
    19045 (Ppp1ca)
 Organismal Systems
  Immune system
   04611 Platelet activation
    19045 (Ppp1ca)
  Endocrine system
   04910 Insulin signaling pathway
    19045 (Ppp1ca)
   04921 Oxytocin signaling pathway
    19045 (Ppp1ca)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    19045 (Ppp1ca)
   04270 Vascular smooth muscle contraction
    19045 (Ppp1ca)
  Nervous system
   04728 Dopaminergic synapse
    19045 (Ppp1ca)
   04720 Long-term potentiation
    19045 (Ppp1ca)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    19045 (Ppp1ca)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    19045 (Ppp1ca)
  Substance dependence
   05031 Amphetamine addiction
    19045 (Ppp1ca)
   05034 Alcoholism
    19045 (Ppp1ca)
  Infectious diseases
   05168 Herpes simplex infection
    19045 (Ppp1ca)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     19045 (Ppp1ca)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     19045 (Ppp1ca)
Transcription machinery [BR:mmu03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     19045 (Ppp1ca)
Spliceosome [BR:mmu03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    19045 (Ppp1ca)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
19; 19 E3-F2
AA seq 330 aa AA seqDB search
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt NT seq  +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactccatcatcgggcgcctgctggaagtgcag
ggctcacggcctgggaagaacgtgcagctgacagagaacgagatccgtggtctgtgcctc
aaatcccgggagattttcctgagccagcccattcttctggagcttgaggcgcccctcaag
atctgtggtgacatccatggccagtactatgaccttctacggctgtttgagtatggtggc
ttccctccagagagcaactacctcttcttgggggattatgtagatcggggcaagcagtct
ttggagaccatctgcctgttgctggcctataagatcagatacccggagaatttctttcta
cttcgtgggaaccatgagtgtgccagcatcaaccgcatttatggcttctatgatgaatgc
aagagaagatacaacatcaaactgtggaagacgttcactgactgcttcaactgcctgccc
attgcagccattgtggatgagaagatcttctgctgccacgggggcctgtctccagacttg
caatccatggagcagattaggcgtattatgcggcccacagacgtgcctgaccagggccta
ctgtgtgatctcctgtggtctgaccctgacaaggatgttcaaggctggggcgagaatgac
cgtggtgtctcctttacctttggggctgaggtggtagccaagttcctgcacaagcatgat
ttggacctcatctgcagagcacatcaggttgtagaagatggctatgagttctttgccaag
agacagttggtgacactcttctcagctcccaactactgtggagagtttgacaatgctggt
gccatgatgagtgtggatgagaccctcatgtgttccttccagatcctcaagcccgctgat
aagaataagggcaagtatgggcagttcagcggcctgaaccccggaggccggcccatcact
ccaccccgcaattctgccaaagccaagaaatag

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