KEGG   Mus musculus (mouse): 19094Help
Entry
19094             CDS       T01002                                 

Gene name
Mapk11, P38b, Prkm11, Sapk2, Sapk2b, p38-2, p38beta, p38beta2
Definition
mitogen-activated protein kinase 11 (EC:2.7.11.24)
Orthology
K04441  
p38 MAP kinase [EC:2.7.11.24]
Organism
mmu  Mus musculus (mouse)
Pathway
MAPK signaling pathway
Rap1 signaling pathway
FoxO signaling pathway
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Platelet activation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
RIG-I-like receptor signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Retrograde endocannabinoid signaling
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Amyotrophic lateral sclerosis (ALS)
Salmonella infection
Pertussis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Tuberculosis
Hepatitis C
Influenza A
Epstein-Barr virus infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    19094 (Mapk11)
   04010 MAPK signaling pathway
    19094 (Mapk11)
   04370 VEGF signaling pathway
    19094 (Mapk11)
   04668 TNF signaling pathway
    19094 (Mapk11)
   04068 FoxO signaling pathway
    19094 (Mapk11)
 Organismal Systems
  Immune system
   04611 Platelet activation
    19094 (Mapk11)
   04620 Toll-like receptor signaling pathway
    19094 (Mapk11)
   04621 NOD-like receptor signaling pathway
    19094 (Mapk11)
   04622 RIG-I-like receptor signaling pathway
    19094 (Mapk11)
   04660 T cell receptor signaling pathway
    19094 (Mapk11)
   04664 Fc epsilon RI signaling pathway
    19094 (Mapk11)
   04670 Leukocyte transendothelial migration
    19094 (Mapk11)
  Endocrine system
   04912 GnRH signaling pathway
    19094 (Mapk11)
   04914 Progesterone-mediated oocyte maturation
    19094 (Mapk11)
   04917 Prolactin signaling pathway
    19094 (Mapk11)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    19094 (Mapk11)
  Nervous system
   04728 Dopaminergic synapse
    19094 (Mapk11)
   04723 Retrograde endocannabinoid signaling
    19094 (Mapk11)
   04722 Neurotrophin signaling pathway
    19094 (Mapk11)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    19094 (Mapk11)
  Development
   04380 Osteoclast differentiation
    19094 (Mapk11)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    19094 (Mapk11)
  Neurodegenerative diseases
   05014 Amyotrophic lateral sclerosis (ALS)
    19094 (Mapk11)
  Infectious diseases
   05132 Salmonella infection
    19094 (Mapk11)
   05133 Pertussis
    19094 (Mapk11)
   05152 Tuberculosis
    19094 (Mapk11)
   05164 Influenza A
    19094 (Mapk11)
   05160 Hepatitis C
    19094 (Mapk11)
   05169 Epstein-Barr virus infection
    19094 (Mapk11)
   05145 Toxoplasmosis
    19094 (Mapk11)
   05140 Leishmaniasis
    19094 (Mapk11)
   05142 Chagas disease (American trypanosomiasis)
    19094 (Mapk11)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     19094 (Mapk11)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: CMGC group
  MAPK family [OT]
   19094 (Mapk11)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
15 E3; 15
AA seq 364 aa AA seqDB search
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSVFHGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPLEPSQLPGTH
EIEQ
NT seq 1095 nt NT seq  +upstreamnt  +downstreamnt
atgtcgggtccgcgcgcgggattctaccggcaagagctgaacaaaacagtatgggaggtg
ccgcagcggctgcagggcctacgcccggtgggctccggcgcctacggctcagtctgctcg
gcctacgacgcgcggctgcgccagaaggtggctgtaaagaagctgtctcgccctttccaa
tcgctgatccacgcgaggaggacataccgtgagctgcgcctactcaagcacctgaagcac
gagaacgtcataggacttttggacgtcttcacgccggccacatccatcgaggatttcagc
gaagtgtacctcgtgacgaccctgatgggcgccgacctgaataacatcgtcaagtgtcag
gccctgagcgatgagcatgttcaattccttgtctaccagctgctgcgtgggctgaagtat
atccactcggcgggcatcatccaccgggacctgaagcccagcaatgtagcggtgaacgag
gactgcgagctgaggatcctggactttgggctagcacgccaggctgatgaggagatgacc
ggatatgtggccacacggtggtaccgggcgccagagatcatgctaaactggatgcactac
aaccagacagtggacatctggtctgtgggctgcatcatggctgaactgctgcaaggaaag
gccctctttcctggaaacgactacatcgaccagctgaagcgaatcatggaggtggtgggc
acgcccagtcctgaggttctggcaaagatatcctcggagcatgcccggacatacatccag
tctctgcctcccatgccccagaaggacctcagcagtgtcttccatggagccaaccccctg
gccatagacctccttggaagaatgctggtactagacagcgaccagagggtcagtgcggcc
gaagccttggcccacgcatacttcagccagtaccatgaccctgacgatgagccagaggca
gagccctatgatgaaagtgttgaggccaaggagcgcacgctggaggagtggaaggagctt
acttaccaagaagtccttagcttcaagcccctggaaccctcacagctccctggcacccat
gaaattgagcagtga

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