KEGG   Mus musculus (mouse): 20662Help
Entry
20662             CDS       T01002                                 

Gene name
Sos1, 4430401P03Rik, 9630010N06, AI449023
Definition
son of sevenless homolog 1 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
mmu  Mus musculus (mouse)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    20662 (Sos1)
   04010 MAPK signaling pathway
    20662 (Sos1)
   04012 ErbB signaling pathway
    20662 (Sos1)
   04630 Jak-STAT signaling pathway
    20662 (Sos1)
   04068 FoxO signaling pathway
    20662 (Sos1)
   04151 PI3K-Akt signaling pathway
    20662 (Sos1)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    20662 (Sos1)
  Cellular commiunity
   04510 Focal adhesion
    20662 (Sos1)
   04540 Gap junction
    20662 (Sos1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    20662 (Sos1)
   04660 T cell receptor signaling pathway
    20662 (Sos1)
   04662 B cell receptor signaling pathway
    20662 (Sos1)
   04664 Fc epsilon RI signaling pathway
    20662 (Sos1)
   04062 Chemokine signaling pathway
    20662 (Sos1)
  Endocrine system
   04910 Insulin signaling pathway
    20662 (Sos1)
   04912 GnRH signaling pathway
    20662 (Sos1)
   04915 Estrogen signaling pathway
    20662 (Sos1)
   04917 Prolactin signaling pathway
    20662 (Sos1)
  Nervous system
   04722 Neurotrophin signaling pathway
    20662 (Sos1)
  Development
   04320 Dorso-ventral axis formation
    20662 (Sos1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    20662 (Sos1)
   05206 MicroRNAs in cancer
    20662 (Sos1)
   05205 Proteoglycans in cancer
    20662 (Sos1)
   05214 Glioma
    20662 (Sos1)
   05221 Acute myeloid leukemia
    20662 (Sos1)
   05220 Chronic myeloid leukemia
    20662 (Sos1)
   05211 Renal cell carcinoma
    20662 (Sos1)
   05215 Prostate cancer
    20662 (Sos1)
   05213 Endometrial cancer
    20662 (Sos1)
   05223 Non-small cell lung cancer
    20662 (Sos1)
  Substance dependence
   05034 Alcoholism
    20662 (Sos1)
  Infectious diseases
   05160 Hepatitis C
    20662 (Sos1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Structure
PDB: 

Jmol
Position
17 E3; 17 50.67 cM
AA seq 1319 aa AA seqDB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLREVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHGHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECMKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASSAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTVLQEEKEEQMRLPSAEVYRFAEPDSEENILFEENVQPKAGIPI
IKAGTVLKLIERLTYHMYADPNFVRTFLTTYRSFCRPQELLSLLIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLRRHGKELINFSK
RRRVAEITGEIQQYQNQPYCLRVEPDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRH
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGTSSNTDVCSVFDSDHSASPFHSRSASVSSISLSKGTDEVPVPPPVP
PRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLL
PPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLP
SPPLTQEMDLHSIAGPPVPPRQSTSQLIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
NT seq 3960 nt NT seq  +upstreamnt  +downstreamnt
atgcaggcgcagcagctgccttacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcaccctactcttgagtct
aatgatgatgctcttcagtatgttgaagaattaattttgcaattactaaatatgctatgc
caagctcagccccggagtgcttcagatgtggaggaacgtgttcaaaagagttttcctcat
ccaattgataagtgggcaatagctgatgcccaatcagccattgaaaagaggaagagacga
aatcctttatcgctgccagcagaaagaattcatcatttattaagggaggtcctcggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagat
attttaaagctcgtggggaattatgtaagaaatatacggcattatgaaattacaaaacaa
gacattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatcttatctttaactgatgaagagccttccacctcaggagaacaaact
tattatgatttggtaaaagcattcatggcagaaattcgacagtatataagagaattaaat
ctaattataaaagtttttcgagagccctttgtctctaattccaaattgttttcatctaat
gatgtagaaaacatattcagtcgtatagtagatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtagaaatgacagatgaaggcagtccccacccattagtagga
agctgttttgaagacttagcagaagaactggcatttgacccgtatgagtcatatgctcgg
gatattttacgacccggattccatggccattttcttagtcagttatcaaagcctggggca
gcactttatttgcagtccataggcgaaggcttcaaagaagctgtccagtacgtcctgccc
cggctgctgcttgcccctgtgtaccactgtctgcattactttgaacttctgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggagtgtatgaagcaagcaataacagccctg
cttaatgtccaaagtggcatggaaaaaatttgctccaaaagtcttgcaaaacgaagacta
agtgagtctgcatgtcggttttacagccagcagatgaaggggaaacagctagccatcaag
aagatgaacgagatccagaagaacattgatggctgggaggggaaggacattggacagtgt
tgcaatgagttcataatggaaggaactcttacacgtgtaggagccaaacacgagagacac
atatttctcttcgatggcttaatgatttgctgtaaatcaaaccatgggcagccaagactc
cctggtgctagcagtgcagaataccggcttaaagaaaagttttttatgcgaaaggtacag
attaatgataaagatgacaccagtgagtacaagcatgcttttgaaatcattctgaaagat
ggcaatagtgttatattttctgccaagtcagctgaagagaaaaacaactggatggcagca
ctgatctctttgcagtaccgcagcaccctggagaggatgctggacgtaacggtgctgcag
gaggagaaggaggagcagatgaggctgcccagtgctgaagtgtacaggtttgcagaacct
gactccgaggagaatattctattcgaagagaatgtgcagcccaaagctgggatccccatt
atcaaggcagggacagtgcttaagctcattgagaggcttacctaccacatgtacgcagat
ccaaattttgttcggacgtttcttacaacatacaggtccttttgcagacctcaagaacta
ctgagtcttctgatagaaagatttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccctgagtgcagagctgaagaggtttagaaaggaa
tatattcagcctgtgcagttgagggtgttaaatgtgtgtcggcactgggtggagcaccat
ttctatgactttgaaagagatgcagaccttttacagagaatggaggaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaagataatccaaaggaaa
aaaattgcaagagacaatggcccaggtcataacattacatttcagagctcacctcccaca
gttgagtggcacataagcagacctgggcacatagagacttttgacttgctcaccttacac
ccaatagaaattgctcggcaactcactttacttgaatcagatctataccgggctgtgcag
ccatcagaattagttggaagtgtgtggacaaaagaagataaagaaattaattctcccaac
cttctgaagatgattcggcacaccactaacctcactttgtggtttgagaaatgtattgta
gaaacagaaaacttagaagaaagagtagctgtagtaagtcggataattgagattctacaa
gtctttcaagagctgaacaacttcaatggtgtcctggaagttgtcagtgctatgaactcg
tcacctgtttacagactagaccacacatttgagcaaataccaagcagacaaaagaaaatt
ttagaagaagctcatgaattgagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccgtgtgtgcctttctttggaatttatctcacaaatatcctgaagaca
gaagagggcaaccctgaggtcctgaggagacacgggaaagagcttattaacttcagcaag
aggaggagagtggccgagatcacaggcgagatccagcagtaccagaaccagccctactgc
ttacgggtggagccggacatcaagaggttctttgaaaacttgaatccaatgggaaacagc
atggagaaagaatttacagactatctgttcaacaaatccctagaaatagaaccccggcac
cctaagcctcttccgagattcccaaaaaaatacagctatcccctaaaatctcctggtgtt
cgtccatcaaatccaagaccaggaaccatgagacatcccacacctctgcagcaggagcca
agaaaaattagctacagtcggattcctgaaagtgagacggaaagcacagcatctgcacca
aactcccctcggaccccactgacgccgccccctgcatctggcacctccagcaacacagat
gtttgcagcgtgttcgattctgaccactcggcaagcccttttcattcaagatctgcttca
gtctcatctataagtttatccaagggcactgatgaagtgcctgtcccccctcctgtaccc
cctcgaagacgtccagagtctgccccagctgaatcctccccatccaagattatgtctaag
cacttggacagccccccagctattcctcctaggcaacccacatccaaagcctattcacca
cgctattcaatatcagatcggacctctatatcagatcctcctgaaagccctcccttgtta
ccaccacgggaacctgtgaggacacctgatgttttctcaagctcaccattacatctccaa
cctcctcctttgggcaaaaagagtgatcatggcaacgccttcttcccaaacagcccatcc
ccttttacaccgccacccccccaaaccccctctcctcatggcacgagaaggcatctgcca
tcaccaccactgacacaggagatggacctccattccattgctgggcctcctgttcctcca
cgacaaagcacttctcaacttatccccaaactccctccaaaaacttacaaaagggagcac
acacacccatccatgcatagagatggaccaccactgctggagaatgcccattcttcctga

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