KEGG   Mus musculus (mouse): 20698Help
Entry
20698             CDS       T01002                                 

Gene name
Sphk1, 1110006G24Rik, Sk1, Spk1
Definition
(RefSeq) sphingosine kinase 1 (EC:2.7.1.91)
  KO
K04718  
sphingosine kinase [EC:2.7.1.91]
Organism
mmu  Mus musculus (mouse)
Pathway
Sphingolipid metabolism
Metabolic pathways
Calcium signaling pathway
Sphingolipid signaling pathway
Phospholipase D signaling pathway
VEGF signaling pathway
Fc gamma R-mediated phagocytosis
Tuberculosis
Module
Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    20698 (Sphk1)
 Environmental Information Processing
  Signal transduction
   04370 VEGF signaling pathway
    20698 (Sphk1)
   04020 Calcium signaling pathway
    20698 (Sphk1)
   04072 Phospholipase D signaling pathway
    20698 (Sphk1)
   04071 Sphingolipid signaling pathway
    20698 (Sphk1)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    20698 (Sphk1)
 Human Diseases
  Infectious diseases
   05152 Tuberculosis
    20698 (Sphk1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphinganine kinase
     20698 (Sphk1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
11; 11 E2
AA seq 382 aa AA seqDB search
MEPVECPRGLLPRPCRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHA
RELVCAEELGHWDALAVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPGGSGNALAASV
NHYAGYEQVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGLRLYSVLSLSWGFVADVDLE
SEKYRRLGEIRFTVGTFFRLASLRIYQGQLAYLPVGTVASKRPASTLVQKGPVDTHLVPL
EEPVPSHWTVVPEQDFVLVLVLLHTHLSSELFAAPMGRCEAGVMHLFYVRAGVSRAALLR
LFLAMQKGKHMELDCPYLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQGQVHPNYLWM
VCGSRDAPSGRDSRRGPPPEEP
NT seq 1149 nt NT seq  +upstreamnt  +downstreamnt
atggaaccagtagaatgccctcgaggactgctcccacggccatgcagagtgctggtgctg
ctgaacccccagggtggcaagggcaaggctctgcagctcttccagagccgtgtgcagccc
ttcctggaggaggcagagataacctttaaactgatactcaccgaacggaagaaccatgcc
agggagctggtgtgtgcagaggagttgggtcactgggacgccctggcagtcatgtccggt
gatggtctgatgcatgaggtggtgaatgggctaatggaacggccagactgggagactgcc
atccagaaacccctgtgtagcctccctggaggctccggcaatgcgctggcagcttctgtg
aaccactatgctgggtacgagcaggtgactaatgaagacctgctcatcaactgcacactg
ctgttgtgccgccggcgcctgtcacccatgaacctgctgtccctgcacactgcttctggg
ctgcggctctattctgtgctcagtctgtcctggggctttgttgctgacgtggacctcgag
agtgagaagtacaggcgcttgggggagattcgtttcacagtgggcaccttctttcgccta
gcaagcctgcgcatctaccaaggccaactggcctaccttcctgtaggaactgtggcctct
aagagacccgcctctacactggtgcagaagggccccgtcgacacacaccttgttcctctg
gaggagccagtgccttctcattggactgtggtaccagaacaggacttcgtcctggtgctg
gtgctgctacacacccacctgagctccgagctgtttgcagcacccatgggccgctgtgag
gctggtgttatgcatctgttctacgtacgtgcgggggtgtcaagggctgcgctgctgcgc
ctcttcctggccatgcagaagggcaagcatatggaacttgactgtccatacctggttcat
gtgcccgtggttgctttccgcctggagcccaggagccagaggggcgtgttttctgtggat
ggagagctgatggtatgtgaagctgtgcagggccaagtgcacccaaactacctttggatg
gtctgtggcagcagagatgccccatccggccgggactcccggcgggggccacctccagaa
gaaccataa

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