KEGG   Mus musculus (mouse): 20698Help
Entry
20698             CDS       T01002                                 

Gene name
Sphk1, 1110006G24Rik, Sk1, Spk1
Definition
sphingosine kinase 1 (EC:2.7.1.91)
Orthology
K04718  
sphingosine kinase [EC:2.7.1.91]
Organism
mmu  Mus musculus (mouse)
Pathway
Sphingolipid metabolism
Metabolic pathways
Calcium signaling pathway
VEGF signaling pathway
Fc gamma R-mediated phagocytosis
Tuberculosis
Module
Sphingosine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    20698 (Sphk1)
 Environmental Information Processing
  Signal transduction
   04370 VEGF signaling pathway
    20698 (Sphk1)
   04020 Calcium signaling pathway
    20698 (Sphk1)
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    20698 (Sphk1)
 Human Diseases
  Infectious diseases
   05152 Tuberculosis
    20698 (Sphk1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.91  sphinganine kinase
     20698 (Sphk1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
11 E2; 11
AA seq 382 aa AA seqDB search
MEPVECPRGLLPRPCRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHA
RELVCAEELGHWDALAVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPGGSGNALAASV
NHYAGYEQVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGLRLYSVLSLSWGFVADVDLE
SEKYRRLGEIRFTVGTFFRLASLRIYQGQLAYLPVGTVASKRPASTLVQKGPVDTHLVPL
EEPVPSHWTVVPEQDFVLVLVLLHTHLSSELFAAPMGRCEAGVMHLFYVRAGVSRAALLR
LFLAMQKGKHMELDCPYLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQGQVHPNYLWM
VCGSRDAPSGRDSRRGPPPEEP
NT seq 1149 nt NT seq  +upstreamnt  +downstreamnt
atggaaccagtagaatgccctcgaggactgctcccacggccatgcagagtgctggtgctg
ctgaacccccagggtggcaagggcaaggctctgcagctcttccagagccgtgtgcagccc
ttcctggaggaggcagagataacctttaaactgatactcaccgaacggaagaaccatgcc
agggagctggtgtgtgcagaggagttgggtcactgggacgccctggcagtcatgtccggt
gatggtctgatgcatgaggtggtgaatgggctaatggaacggccagactgggagactgcc
atccagaaacccctgtgtagcctccctggaggctccggcaatgcgctggcagcttctgtg
aaccactatgctgggtacgagcaggtgactaatgaagacctgctcatcaactgcacactg
ctgttgtgccgccggcgcctgtcacccatgaacctgctgtccctgcacactgcttctggg
ctgcggctctattctgtgctcagtctgtcctggggctttgttgctgacgtggacctcgag
agtgagaagtacaggcgcttgggggagattcgtttcacagtgggcaccttctttcgccta
gcaagcctgcgcatctaccaaggccaactggcctaccttcctgtaggaactgtggcctct
aagagacccgcctctacactggtgcagaagggccccgtcgacacacaccttgttcctctg
gaggagccagtgccttctcattggactgtggtaccagaacaggacttcgtcctggtgctg
gtgctgctacacacccacctgagctccgagctgtttgcagcacccatgggccgctgtgag
gctggtgttatgcatctgttctacgtacgtgcgggggtgtcaagggctgcgctgctgcgc
ctcttcctggccatgcagaagggcaagcatatggaacttgactgtccatacctggttcat
gtgcccgtggttgctttccgcctggagcccaggagccagaggggcgtgttttctgtggat
ggagagctgatggtatgtgaagctgtgcagggccaagtgcacccaaactacctttggatg
gtctgtggcagcagagatgccccatccggccgggactcccggcgggggccacctccagaa
gaaccataa

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