KEGG   Mus musculus (mouse): 20927Help
Entry
20927             CDS       T01002                                 

Gene name
Abcc8, D930031B21Rik, SUR1, Sur
Definition
(RefSeq) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
  KO
K05032  
ATP-binding cassette subfamily C (CFTR/MRP) member 8
Organism
mmu  Mus musculus (mouse)
Pathway
ABC transporters
Insulin secretion
Type II diabetes mellitus
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Membrane transport
   02010 ABC transporters
    20927 (Abcc8)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    20927 (Abcc8)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    20927 (Abcc8)
Transporters [BR:mmu02000]
 ABC Transporters, Eukaryotic Type
  ABCC (CFTR/MRP) subfamily
   ABCC8, 9 subgroups
    20927 (Abcc8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
MGI: 
Ensembl: 
Vega: 
Position
7 B3; 7 29.66 cM
AA seq 1581 aa AA seqDB search
MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHI
HHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITS
VVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYG
MLLLVEINVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTA
HRKPIDLRAIGKLPIAMRALTNYQRLCAAFDAQARKDTQSQQGARAIWRALCHAFGRRLV
LSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAV
LLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNL
VAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATK
LSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEMTRRKEMTSLRAFAVYT
SISIFMNTAIPIAAVLITFVGHVSFFKESDFSPSVAFASLSLFHILVTPLFLLSSVVRST
VKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLL
GPLQRLTPSMDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKS
SLLLATLGEMQRVSGAVFWNSLPDSEGEDPSNPERETAADSDARSRGPVAYASQKPWLLN
ATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVA
RALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWII
AMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMS
SRDGLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGVLLLSLLVFSQL
LKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECALDQSVYAMVFTVLCSLGIALCLV
TSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLE
CLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLL
SHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVL
IAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKT
EAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRT
GSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLD
PEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTS
IFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFD
KPEKLLSQKDSVFASFVRADK
NT seq 4746 nt NT seq  +upstreamnt  +downstreamnt
atgcccttggccttctgcggcaccgagaaccactcggccgcctaccgggtggaccaaggt
gtcctcaacaacggctgcttcgtggacgcgctcaacgtagtgccacatgtcttcctgctc
ttcatcacattccccatcctcttcatcggatggggcagccagagctccaaggtacacatt
caccatagcacctggctccatttccctggccacaacctgcgctggatccttaccttcatg
ctgctctttgtcctggtgtgtgagatcgctgagggtatcctgtctgatggggtgacagaa
tcccgccacctccatttgtacatgccagctgggatggctttcatggctgccatcacctct
gtggtctactatcacaacattgagacctctaacttccccaagctgctgatcgctctgctt
atctactggaccttggccttcatcactaagaccatcaagttcgtcaagttctacgaccac
gccatcggcttctctcagctgcgcttctgcctcacggggcttctggtgatcctctacggg
atgctgctgctggtggagatcaatgtcatccgggtgcggaggtacatcttcttcaagacg
ccaagggaagtgaagccccctgaggacctgcaggacctgggggtgcgctttctgcagccc
ttcgtgaatctgctgtcaaaggggacctactggtggatgaatgccttcatcaagactgcc
cacaggaagcccatcgacctgcgggccatcgggaagctgcccatcgccatgagagccctc
accaactatcagcgactctgcgcggccttcgatgcccaggcgcggaaagacacgcagagc
cagcagggcgcccgggccatctggagggctctctgccatgcctttgggagacgcctggtc
ctcagcagcacattccgtatcctggctgacctgctgggctttgctggaccgctctgcatc
tttgggatcgtggaccacctcgggaaggagaaccatgtcttccagcccaagacacagttt
cttggggtttactttgtctcgtcccaagagttcctgggcaacgcctatgtcttggctgta
cttctgttcctggccctcctgctgcaaaggacgttcctgcaagcctcgtactacgtcgcc
attgaaactgggattaacctgagaggggcgatccagaccaagatttacaataagatcatg
cacttgtctacttccaacctgtcaatgggggagatgacggctgggcagatctgcaacctg
gtggccatcgacacaaatcagctcatgtggtttttcttcttatgcccaaacctctgggct
atgccagtacagatcattgtgggcgtgatcctcctctactacatccttggggtcagtgcc
ttgattggagcagctgtcatcattctgctggctcctgtacagtactttgtggccaccaag
ctctcccaggcacagcggagcaccctggaatattccaatgaaaggctgaagcagaccaac
gagatgctccggggcatcaaactgctcaaactgtacgcgtgggagaacatcttctgctcg
agggtggagatgacgcgcaggaaggaaatgaccagcctcagagccttcgctgtctacacc
tccatctccatcttcatgaacacagctatccccattgctgccgtcctcattacctttgtg
ggccacgtcagcttcttcaaagagtcagacttctcaccctcggtggcctttgcctctctc
tctctcttccacatcctggtcacaccgctgttcctgctgtctagtgtggttcggtccacc
gtcaaggccctagtgagtgtgcaaaagctgagtgagttcctgtccagtgcagagatccgt
gaggaacagtgtgccccccgagagcctgcaccccaaggccaagcgggcaagtaccaggcg
gtgcccctcaaggttgtgaaccgcaagcgcccagcccgggaagaggttcgggacctcttg
ggcccactgcagaggctgacccccagcatggatggagatgctgacaacttctgtgtccag
atcatcggaggcttcttcacctggacccctgatggaatccccaccctgtccaacatcacc
atccgtatcccccgaggccagctgaccatgattgtggggcaggtgggctgcggcaagtcc
tcgctccttctggccaccctgggggagatgcagagggtctccggggccgtcttctggaac
agccttccagacagcgagggagaagaccccagcaacccagagcgggagacagcagccgac
tcggatgccaggagcagaggccccgtagcctacgcatctcagaaaccatggctgctaaat
gccacggtggaggagaacatcaccttcgagagtcccttcaataagcaaaggtacaagatg
gtcatcgaagcctgctccctgcagccagacatagacatcttaccccatggagaccagact
cagattggggaacggggcatcaacttgtctggtggtcagcgtcagcgaatcagtgtagcc
cgagccctctaccagcacaccaatgttgtcttcttggatgaccctttctcagctctggat
gtccatctgagcgaccacctgatgcaggctggcatccttgagctgctccgggatgacaag
aggacagtggtcttggtgacccacaagctacagtacctgcctcatgcagactggatcatt
gctatgaaggatggcaccattcagagggaggggacgctcaaggacttccagaggtctgag
tgccagctctttgagcattggaagaccctcatgaacaggcaagaccaagagctggagaag
gagacagtcatggagaggaaagccccagaaccgtctcagggcctgccccgtgccatgtcc
tcaagagatggccttctgctggatgaggacgaggaggaagaggaggcggccgagagcgag
gaagatgacaacttatcttcggtgctgcatcagcgagccaagatcccatggcgggcctgc
actaagtatttgtcctctgccggcgtcctgctcttgtccctgcttgtcttctcccagcta
ctcaagcacatggtcttggtggccattgattactggctggccaagtggacggacagtgcc
ctggtcctgagccctgctgccaggaactgctccctcagccaggaatgcgccctggaccag
tctgtctatgccatggtattcaccgtgctctgcagcctgggaattgcactgtgccttgtc
acctctgtcactgtggagtggacaggactgaaggtggccaagaggctgcaccgcagcctg
ctcaatcgcatcatcctggcccccatgaggttctttgagaccacgcccctggggagtatc
ctgaacagattttcatctgactgtaacaccattgaccagcacatcccatccacgctggag
tgtctgagccgatccactctactctgtgtctccgccttgactgtcatctcctacgtcaca
cctgtgttcctcgtggccctcttacccctagctgtggtgtgctacttcatccagaaatac
ttccgagtggcgtccagggacctgcagcagctggatgacacaacgcagctccctctgctc
tcacactttgctgaaaccgtggaaggactcaccaccatccgtgccttcaggtacgaggcc
cggttccagcagaagctcctggagtacacggactccaacaacatcgcctccctcttcctc
acggcagccaacaggtggctagaagtccgcatggagtacattggagcatgcgtggtactc
atcgcagccgccacctccatctccaactccctgcacagggagctctctgctggtctggtg
ggcctgggcctcacctacgccttgatggtctccaactacctcaactggatggtgaggaac
ctggcagacatggagatccaattgggggctgtgaagcgcatccacacactcctgaaaact
gaggcagagagctatgaggggctcctagcaccgtcattgatccccaagaactggccagac
caagggaagattcaaattcaaaacctgagtgtgcgctatgacagctccctgaagcccgtg
ctgaagcacgtcaatgccctcatcgccccaggacagaagatcgggatctgcggccgcaca
ggcagtgggaagtcctccttctctctcgcctttttccgaatggtggacatgttcgaaggg
cgcatcatcattgatggcatcgacatcgccaagctgccgctgcacacgctccgttcacgc
ctctccatcatcctacaggaccctgtcctcttcagcggcaccatcagattcaacctggac
ccagagaagaaatgctcagacagcacactctgggaggctctggagatcgcccagctgaag
ctggtggtgaaggcactgccaggaggcctggatgccatcatcacagaaggaggggagaat
tttagtcaaggtcagaggcagctgttctgcctggctcgggccttcgtgagaaagaccagc
atcttcatcatggacgaagcaactgcctccattgacatggctacggaaaacatcctccag
aaggtggtgatgacagccttcgcagaccgcactgtggtcaccatcgcgcaccgcgtacac
accatcctgagtgcagacctcgtgatggtcctgaagaggggagccatcctggagtttgac
aaaccggagaagcttctgagccagaaggacagcgtcttcgcctccttcgtccgcgcggac
aaatga

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