KEGG   Mus musculus (house mouse): 212032
Entry
212032            CDS       T01002                                 
Symbol
Hk3, HK_III, HK-III
Name
(RefSeq) hexokinase 3
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00010  Glycolysis / Gluconeogenesis
mmu00051  Fructose and mannose metabolism
mmu00052  Galactose metabolism
mmu00500  Starch and sucrose metabolism
mmu00520  Amino sugar and nucleotide sugar metabolism
mmu00524  Neomycin, kanamycin and gentamicin biosynthesis
mmu01100  Metabolic pathways
mmu01200  Carbon metabolism
mmu01250  Biosynthesis of nucleotide sugars
mmu04066  HIF-1 signaling pathway
mmu04910  Insulin signaling pathway
mmu04930  Type II diabetes mellitus
mmu04973  Carbohydrate digestion and absorption
mmu05230  Central carbon metabolism in cancer
Module
mmu_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mmu_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
mmu_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    212032 (Hk3)
   00051 Fructose and mannose metabolism
    212032 (Hk3)
   00052 Galactose metabolism
    212032 (Hk3)
   00500 Starch and sucrose metabolism
    212032 (Hk3)
   00520 Amino sugar and nucleotide sugar metabolism
    212032 (Hk3)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    212032 (Hk3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    212032 (Hk3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    212032 (Hk3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    212032 (Hk3)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    212032 (Hk3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    212032 (Hk3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    212032 (Hk3)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     212032 (Hk3)
Membrane trafficking [BR:mmu04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    212032 (Hk3)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1 RIX1
Other DBs
NCBI-GeneID: 212032
NCBI-ProteinID: NP_001028417
MGI: 2670962
Ensembl: ENSMUSG00000025877
UniProt: Q3TRM8
Position
13:complement(55153798..55169233)
AA seq 922 aa
MATIGPSGLHPGERASVCPHEGVPRPSGSLELECLQQFKVTRTQLQQIQASLLCSMEQAL
KGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKECRVEPRS
REFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVENQGLKLGFNFSFPCHQTGLDRSTLI
SWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDVVAMVNDTVGTMMGCELGTRPCEVGLI
VDTGTNACYMEEARHVAALDEDRGRTCVSIEWGSFYDEDALGPVLTTFDSALDRESLTPG
AQRFEKMIGGLYLGELVRLVLVHLTQHGVLFDGCASPALLSQGCILLDHVAEMEDTATGT
ARVHTILQDLGLSPRASDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVA
VATGGRVFERHPRFLRILKETVTLLAPNCDVSFIPSVDGGGRGVAMVTAVAARLAAHRRI
LEETLAPFQLTLEQMTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALD
LGGTNFRVLLVRVAEGSVQIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLSGQS
LPLGFTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIV
NDTVGTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPGDSGLMCINMEWGAFGDD
GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC
LQARDIFKTKFLSEIESDSLALRQVRAILEDLGLTLTSDDALMVLEVCQAVSRRAAQLCG
AGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATVRKLAPQCTVTFLQSED
GSGKGAALVTAVACRLTQMAHV
NT seq 2769 nt   +upstreamnt  +downstreamnt
atggccaccattgggccttctggcctgcatcctggagaaagagcctcagtctgcccacac
gagggcgtgccaaggccctcaggtagcttagaactggaatgcttgcagcaattcaaggtg
accaggacacagttgcagcagatccaagccagtctcctgtgctccatggagcaggcactg
aagggacaggacagtcccgctccttctgtccggatgctgcccacatacgtgaggtccaca
ccacacggcaccgagcaaggggatttcctggtgctggagctgggggccacaggagcatca
ctacgtgtgttgtgggtaacactgacaggcaccaaagaatgccgggtggagcccaggagc
cgggagtttgtgattcctcaagaggtgatcctaggtgctggccagcagctctttgacttt
gctgcccgatgcctctctgaattcctggatgcataccccgtggagaatcagggtctgaag
cttgggttcaatttctcttttccttgtcaccagacaggcttggacaggagcaccctcatt
tcctggacaaaaggttttaggtgcagcggcgtggaaggccaggatgtggtccagttgcta
agagatgccattcagaggcaggggacctacaggattgatgtggtagccatggtgaatgac
acggtgggcaccatgatgggctgtgagctgggcaccaggccgtgtgaagtcgggctgatt
gtagacaccggtaccaacgcgtgctacatggaggaggcgcggcacgtggccgctctggat
gaggaccgcggccgcacctgtgtcagcatcgagtggggctccttctatgacgaagatgct
ctagggccagtactgaccaccttcgactctgccctggaccgcgagtccctgactcctggt
gctcaaaggtttgagaagatgattggaggcctttacctgggtgagctggtgaggctggtt
ctggtccacttgacccagcacggggtcctctttgatggctgcgcctctcctgcgttgctg
agtcaaggctgtatcctcctggaccacgtggctgagatggaggacaccgccactgggaca
gcccgcgtccacaccatcctgcaggacttgggtctgagccctcgggcctcagatgctgaa
ctggtgcaatatgtgtgcgtggctgtgtgcacacgggctgcccagctctgtgcggctgcc
ctggctgcagtcctctcccgcctccagcacagcagggagcagcagacattgcaagtggct
gtggccactggagggcgagtgtttgaacgacaccccaggttcctccgaatcctaaaggag
acggtaacactcctggccccaaactgtgatgtctccttcatcccctctgtggatggtggt
ggccggggtgtggcaatggtgacagctgtggctgcccgcctggctgctcacaggcgcatc
ctggaagagaccctggcaccatttcagctgaccttggagcagatgacagtggtgcaggca
caaatgcgggaagccatgatcagggggcttcaaggagaggcctcctccctccgcatgctg
cccacttacgtccgagcgacgcccgacggcagcgagcgaggtgatttcctggccttggac
ctagggggcaccaacttccgggtcctgttggtacgagtggcggagggcagtgtgcagatc
atcaaccaggtctactccattcctgagtgtagagcccagggctctggacagaagctcttt
gaccatattgtggactgcatcgtggacttccagaagaggcagggccttagtggacagagc
ctacccctgggtttcaccttctctttcccatgcaagcagcttggcctggaccagggcatc
ctcctgaattggactaaggggttcaatgcatcaggctgtgagggccaggatgttgtgtat
ctattacgggaagccattaggcgcagacaggcagtggagctgaatgtggttgccattgtc
aatgacacggtggggaccatgatgtcctgtggctatgatgatccccgttgtgagatgggc
ctcattgtcggaaccggcaccaacgcctgttacatggaagagctccgcaatgtggcaagt
gtgcctggggactcgggcctcatgtgcatcaacatggagtggggtgcctttggggatgat
ggctcactgggcacactcagcacccgctttgacaccagtgtggaccaggcatccatcaat
ccaggcaaacagaggtttgagaaaatgatcagcggtatgtacttgggggagatcgtccgc
catatcctcctgcacttaaccaatctcggagttctcttccgaggccagaagactcaatgc
cttcaggccagggacatcttcaagactaagttcctctctgagatcgaaagtgatagcctg
gccctgcgtcaggtccgagccatcctggaagatctggggctgactctgacatctgatgac
gccttgatggtcctggaagtgtgccaggctgtgtctcgcagggctgcccaactctgtggg
gcaggtgtggctgccgtggtggagaagattcgggagaaccggggcctgcaggagctgaca
gtgtctgtgggagtagatgggacactctacaagctacatcctcacttctccaagctggtg
tcggcaacagtccggaagctagcccctcagtgcaccgtcacctttttgcagtcggaggat
gggtctggcaaaggcgcagctttggttactgctgttgcttgtcgccttacccagatggcc
cacgtctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (17)   
   KEGG PATHWAY (14)   
   KEGG MODULE (3)   
Chemical substance (16)   
   KEGG COMPOUND (16)   
Chemical reaction (9)   
   KEGG ENZYME (1)   
   KEGG REACTION (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (46)   
   RefSeq(nuc) (6)   
   GenBank (20)   
   EMBL (20)   
Protein domain (3)   
   Pfam (3)   
All databases (115)   

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