KEGG T01002: 22371

Mus musculus (mouse): 22371

Entry

22371 CDS T01002

Gene name

Vwf, 6820430P06Rik, AI551257, B130011O06Rik, C630030D09, F8VWF, VWD

Definition

Von Willebrand factor homolog

Orthology

K03900

von Willebrand factor

Organism

mmu Mus musculus (mouse)

Pathway

mmu04151	PI3K-Akt signaling pathway
mmu04510	Focal adhesion
mmu04512	ECM-receptor interaction
mmu04610	Complement and coagulation cascades

Class

Environmental Information Processing; Signal transduction; PI3K-Akt signaling pathway [PATH:mmu04151]
Environmental Information Processing; Signaling molecules and interaction; ECM-receptor interaction [PATH:mmu04512]
Cellular Processes; Cell communication; Focal adhesion [PATH:mmu04510]
Organismal Systems; Immune system; Complement and coagulation cascades [PATH:mmu04610]

SSDB

Motif

Pfam:

VWD VWA C8 TIL VWC VWA_3

Other DBs

NCBI-GI:

NCBI-GeneID:

MGI:

Ensembl:

Vega:

UniProt:

Structure

PDB:

1U0O

Position

6 F3; 6 59.32 cM

AA seq 2813 aa
MNPFRYEICLLVLALTWPGTLCTEKPRDRPSTARCSLFGDDFINTFDETMYSFAGGCSYL
LAGDCQKRSFSILGNFQDGKRMSLSVYLGEFFDIHLFANGTVTQGDQSISMPYASQGLYL
EREAGYYKLSSETFGFAARIDGNGNFQVLMSDRHFNKTCGLCGDFNIFAEDDFRTQEGTL
TSDPYDFANSWALSSEEQRCKRASPPSRNCESSSGDMHQAMWEQCQLLKTASVFARCHPL
VDPESFVALCEKILCTCATGPECACPVLLEYARTCAQEGMVLYGWTDHSACRPACPAGME
YKECVSPCPRTCQSLSINEVCQQQCVDGCSCPEGELLDEDRCVQSSDCPCVHAGKRYPPG
TSLSQDCNTCICRNSLWICSNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCED
HTFSIVIETMQCADDPDAVCTRSVSVRLSALHNSLVKLKHGGAVGIDGQDVQLPFLQGDL
RIQHTVMASVRLSYAEDLQMDWDGRGRLLVKLSPVYSGKTCGLCGNYNGNKGDDFLTPAG
LVEPLVVDFGNAWKLQGDCSDLRRQHSDPCSLNPRLTRFAEEACALLTSSKFEACHHAVS
PLPYLQNCRYDVCSCSDSRDCLCNAVANYAAECARKGVHIGWREPGFCALGCPQGQVYLQ
CGNSCNLTCRSLSLPDEECSEVCLEGCYCPPGLYQDERGDCVPKAQCPCYYDGELFQPAD
IFSDHHTMCYCEDGFMHCTTSGTLGSLLPDTVLSSPLSHRSKRSLSCRPPMVKLVCPADN
PRAQGLECAKTCQNYDLECMSLGCVSGCLCPPGMVRHENKCVALERCPCFHQGAEYAPGD
TVKIGCNTCVCRERKWNCTNHVCDATCSAIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS
NPGTFQILVGNEGCSYPSVKCRKRVTILVDGGELELFDGEVNVKRPLRDESHFEVVESGR
YVILLLGQALSVVWDHHLSISVVLKHTYQEQVCGLCGNFDGIQNNDFTTSSLQVEEDPVN
FGNSWKVSSQCADTRKLSLDVSPATCHNNIMKQTMVDSACRILTSDVFQGCNRLVDPEPY
LDICIYDTCSCESIGDCACFCDTIAAYAHVCAQHGQVVAWRTPTLCPQSCEEKNVRENGY
ECEWRYNSCAPACPVTCQHPEPLACPVQCVEGCHAHCPPGRILDELLQTCVDPQDCPVCE
VAGRRLAPGKKITLSPDDPAHCQNCHCDGVNLTCEACQEPGGLVAPPTDAPVSSTTPYVE
DTPEPPLHNFYCSKLLDLVFLLDGSSMLSEAEFEVLKAFVVGMMERLHISQKRIRVAVVE
YHDGSRAYLELKARKRPSELRRITSQIKYTGSQVASTSEVLKYTLFQIFGKIDRPEASHI
TLLLTASQEPPRMARNLVRYVQGLKKKKVIVIPVGIGPHASLKQIRLIEKQAPENKAFLL
SGVDELEQRRDEIVSYLCDLAPEAPAPTQPPQVAHVTVSPGIAGISSPGPKRKSMVLDVV
FVLEGSDEVGEANFNKSKEFVEEVIQRMDVSPDATRISVLQYSYTVTMEYAFNGAQSKEE
VLRHVREIRYQGGNRTNTGQALQYLSEHSFSPSQGDRVEAPNLVYMVTGNPASDEIKRLP
GDIQVVPIGVGPHANMQELERISRPIAPIFIRDFETLPREAPDLVLQTCCSKEGLQLPTL
PPLPDCSQPLDVVLLLDGSSSLPESSFDKMKSFAKAFISKANIGPHLTQVSVIQYGSINT
IDVPWNVVQEKAHLQSLVDLMQQEGGPSQIGDALAFAVRYVTSQIHGARPGASKAVVIII
MDTSLDPVDTAADAARSNRVAVFPVGVGDRYDEAQLRILAGPGASSNVVKLQQVEDLSTM
ATLGNSFFHKLCSGFSGVCVDEDGNEKRPGDVWTLPDQCHTVTCLANGQTLLQSHRVNCD
HGPRPSCANSQSPVRVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVIFQNK
EQDLEVLLHNGACSPGAKQACMKSIEIKHAGVSAELHSNMEMAVDGRLVLAPYVGENMEV
SIYGAIMYEVRFTHLGHILTYTPQNNEFQLQLSPKTFASKMHGLCGICDENGANDFTLRD
GTVTTDWKRLVQEWTVQQPGYTCQAVPEEQCPVSDSSHCQVLLSASFAECHKVIAPATFH
TICQQDSCHQERVCEVIASYAHLCRTSGVCVDWRTTDFCAMSCPPSLVYNHCERGCPRHC
DGNTSFCGDHPSEGCFCPQHQVFLEGSCVPEEACTQCVGEDGVRHQFLETWVPDHQPCQI
CMCLSGRKINCTAQPCPTARAPTCGPCEVARLKQSTNLCCPEYECVCDLFNCNLPPVPPC
EGGLQPTLTNPGECRPTFTCACRKEECKRVSPPSCPPHRTPTLRKTQCCDEYECACSCVN
STLSCPLGYLASATTNDCGCTTTTCLPDKVCVHRGTVYPVGQFWEEGCDTCTCTDMEDTV
VGLRVVQCSQRPCEDSCQPGFSYVLHEGECCGRCLPSACKVVAGSLRGDSHSSWKSVGSR
WAVPENPCLVNECVRVEDAVFVQQRNISCPQLAVPTCPTGFQLNCETSECCPSCHCEPVE
ACLLNGTIIGPGKSVMVDLCTTCRCIVQTDAISRFKLECRKTTCEACPMGYREEKSQGEC
CGRCLPTACTIQLRGGRIMTLKQDETFQDGCDSHLCRVNERGEYIWEKRVTGCPPFDEHK
CLAEGGKIVKIPGTCCDTCEEPDCKDITAKVQYIKVGDCKSQEEVDIHYCQGKCASKAVY
SIDIEDVQEQCSCCLPSRTEPMRVPLHCTNGSVVYHEVINAMQCRCSPRNCSK

NT seq 8442 nt +upstreamnt +downstreamnt
atgaaccctttcaggtatgagatctgcctgcttgttctggccctcacctggccagggacc
ctctgcacagaaaagccccgtgacaggccgtcgacggcccgatgcagcctctttggggac
gacttcatcaacacgtttgatgagaccatgtacagctttgcagggggctgcagttatctc
ctggctggggactgccagaaacgttccttctccattctcgggaacttccaagatggcaag
agaatgagcctgtctgtgtatcttggggagttttttgacatccatttgtttgccaatggc
accgtaacgcagggtgaccaaagcatctccatgccctacgcctcccaaggactctaccta
gaacgcgaggctgggtactataagctctccagtgagacctttggctttgcggccagaatc
gatggcaatggcaacttccaagtcctgatgtcagacagacacttcaacaagacctgtggg
ctgtgcggtgattttaacatcttcgcggaagatgattttaggacgcaggaggggaccttg
acctcagacccctatgattttgccaactcctgggccctgagcagtgaggaacagcggtgt
aaacgggcatctcctcccagcaggaactgcgagagctcttctggggacatgcatcaggcc
atgtgggagcaatgccagctactgaagacggcatcggtgtttgcccgctgccaccctctg
gtggatcccgagtcctttgtggctctgtgtgagaagattttgtgtacgtgtgctacgggg
ccagagtgcgcatgtcctgtactccttgagtatgcccgaacctgcgcccaggaagggatg
gtgctgtacggctggactgaccacagtgcctgtcgtccagcttgcccagctggcatggaa
tataaggagtgtgtgtctccttgccccagaacctgccagagcctgtctatcaatgaagtg
tgtcagcagcaatgtgtagacggctgtagctgccctgagggagagctcttggatgaagac
cgatgtgtgcagagctccgactgtccttgcgtgcacgctgggaagcggtaccctcctggc
acctccctctctcaggactgcaacacttgtatctgcagaaacagcctatggatctgcagc
aatgaggaatgcccaggggagtgtcttgtcacaggccaatcgcacttcaagagcttcgac
aacaggtacttcaccttcagtgggatctgccaatatctgctggcccgggactgcgaggat
cacactttctccattgtcatagagaccatgcagtgtgccgatgaccctgatgctgtctgc
acccgctcggtcagtgtgcggctctctgccctgcacaacagcctggtgaaactgaagcac
gggggagcagtgggcatcgatggtcaggatgtccagctccccttcctgcaaggtgacctc
cgcatccagcacacagtgatggcttctgtacgcctcagctatgcggaggacctgcagatg
gactgggatggccgtgggcggctactggttaagctgtccccagtctattctgggaagacc
tgtggcttgtgtgggaattacaacggcaacaagggagacgacttcctcacgccggccggc
ttggtggagcccctggtggtagacttcggaaacgcctggaagcttcaaggggactgttcg
gacctgcgcaggcaacacagcgacccctgcagcctgaatccacgcttgaccaggtttgca
gaggaggcttgtgcgctcctgacgtcctccaagttcgaggcctgccaccacgcagtcagc
cctctgccctatctgcagaactgccgttatgatgtttgctcctgctccgacagccgggat
tgcctgtgtaacgcagtagctaactatgctgccgagtgtgcccgaaaaggcgtgcacatc
gggtggcgggagcctggcttctgtgctctgggctgtccacagggccaggtgtacctgcag
tgtgggaattcctgcaacctgacctgccgctccctctccctcccggatgaagaatgcagt
gaagtctgtcttgaaggctgctactgcccaccagggctctaccaggatgaaagaggggac
tgtgtgcccaaggcccagtgcccctgctactacgatggtgagctcttccagcctgcggac
attttctcagaccaccataccatgtgttactgtgaagatggcttcatgcactgtaccaca
agtggcaccctggggagcctgttgcctgacactgtcctcagcagtcccctgtctcaccgt
agcaaaaggagcctttcctgccggccacccatggtcaagctggtgtgtcctgctgacaac
ccacgggctcaagggctggagtgtgctaagacgtgccagaactacgacctggagtgtatg
agcctgggctgtgtgtctggctgcctctgtcccccaggcatggtccggcacgaaaacaag
tgtgtggccttggagcggtgtccctgcttccatcagggtgcagagtacgccccgggagac
acagtgaagattggctgcaacacctgtgtctgccgggagcggaagtggaactgcacgaac
catgtgtgtgacgccacttgctctgccattggtatggcccactacctcaccttcgatgga
ctcaagtacctgttcccgggggagtgccagtatgttctggtgcaggattactgtggcagt
aaccctgggacctttcagatcctggtgggaaatgagggttgcagctatccctcggtgaag
tgcaggaagcgggtgaccatcctggtggatggaggggagcttgaactgtttgacggagag
gtgaacgttaagaggcccctgagagatgaatctcactttgaggtggtggagtcgggccgg
tacgtcatcctgctgctgggtcaggccctttctgtggtctgggaccaccacctcagcatc
tctgtggtcctgaagcacacataccaggaacaggtgtgtggcctctgcgggaactttgat
ggcatccagaacaatgacttcaccactagcagcctccaggtggaggaagaccccgtcaac
tttgggaactcctggaaagtgagctcacagtgtgctgacacgagaaagctgtcactagat
gtttcccctgccacttgccacaacaacatcatgaaacagacgatggtggactcagcctgc
agaatccttaccagtgacgtcttccagggctgcaacaggctggtggaccctgagccatac
ctggacatctgtatttatgacacttgctcctgtgagtccatcggggactgcgcctgtttc
tgtgacaccattgctgcctatgcccacgtgtgtgcccagcatggccaggtggtagcctgg
aggacacccacactgtgcccccagagctgtgaagaaaagaatgttcgggaaaatggctat
gagtgtgagtggcgttataacagctgtgcgcctgcttgcccagtcacgtgtcagcaccct
gagcctctggcttgccctgtgcagtgtgtggagggttgtcatgcacattgccctccaggg
agaatcctggatgaacttctgcagacctgcgtagacccccaagactgccccgtgtgtgag
gtggctggtcggcgcttggctcctggaaagaaaatcaccttgagtcctgatgaccctgca
cactgtcagaattgtcactgtgatggtgtgaaccttacgtgtgaagcctgccaagagccc
ggaggcctggtggcacccccaactgatgccccagtcagctctaccaccccatatgttgag
gatacccccgagccccccctgcacaacttctactgcagcaagctgctggatcttgtcttc
ctgctggatggctcctctatgttgtccgaggctgagtttgaagtgctcaaagcttttgtg
gtgggcatgatggagaggttacacatctctcagaagcgcatccgcgtggcagtggtagag
taccatgatggctcccgtgcctaccttgagctcaaggcccggaagcgaccctcagagctt
cggcgcatcaccagccagattaagtatacaggcagccaggtggcctctaccagtgaggtt
ttgaagtacacactgttccagatctttggcaaaattgaccgccctgaagcctcccatatc
actctgctcctgactgctagccaggagcccccacggatggctaggaatttggtccgctat
gtccaaggtctgaagaagaagaaggttatcgtgatccctgtgggcattgggccccacgcc
agcctcaaacagatccgcctcatcgagaagcaggcccctgaaaacaaggcttttctgctc
agtggggtggatgagctggagcagagaagagatgagatagtcagctacctctgtgacctt
gctcccgaggccccagccccaactcagcctccacaggtagcccacgtcaccgtgagtcca
gggatcgctgggatctcgtcaccgggaccaaaacggaagtccatggttctggatgtggtg
tttgtcctggaggggtcagacgaagttggtgaagccaacttcaataagagcaaggagttc
gtggaggaggtaatccagcgcatggacgtgagcccggatgcaacgcgcatctcagtactg
cagtattcctacacggtaaccatggagtatgccttcaatggggcccagtccaaggaggag
gtgctgcggcacgtgcgagagatccgctaccagggcggcaataggacaaacactgggcag
gccctgcagtacctttctgagcacagcttctctcccagccaaggggaccgggtagaggca
cctaacctggtctacatggtcacggggaaccccgcctctgatgagatcaagaggttgcct
ggagacatccaggtggtacccattggggtgggcccccatgccaacatgcaggaactggag
aggatcagcaggcccatcgctcccatcttcatccgggactttgagacacttccccgagag
gctcctgacctggtcctgcagacatgttgctccaaggagggtctgcaactgcccaccctc
ccccctctccctgactgcagccaacccctggatgtggtcctgctcctggatggctcctct
agcttgccagagtcttcctttgataaaatgaagagttttgccaaggctttcatttcaaag
gccaacattgggccccacctcacacaggtgtccgtgatacagtatggaagcatcaatacc
attgatgtaccatggaatgtggttcaggagaaagcccatctacagagtttggtggacctc
atgcagcaggagggtggccccagccagattggggatgctctggcctttgccgtgcgctat
gtaacttcacaaatccacggagccaggcctggggcctccaaagcagtggtcatcatcatc
atggatacctccttggatcccgtggacacagcagcagatgctgccagatccaaccgagtg
gcagtgtttcccgttggggttggggatcggtatgatgaagcccagctgaggatcttggca
ggccctggggccagctccaatgtggtaaagctccagcaagttgaagacctctccaccatg
gccaccctgggcaactccttcttccacaaactgtgttctgggttttctggagtttgtgtg
gatgaagatgggaatgagaagaggcctggggatgtctggaccttgccggatcagtgccac
acagtgacttgcttggcaaatggccagaccttgctgcagagtcatcgtgtcaattgtgac
catggaccccggccttcatgtgccaacagccagtctcctgttcgggtggaggagacgtgt
ggctgccgctggacctgcccttgtgtgtgcacgggcagttccactcggcacatcgtcacc
ttcgatgggcagaatttcaagcttactggtagctgctcctatgtcatctttcaaaacaag
gagcaggacctggaagtgctcctccacaatggggcctgcagccccggggcaaaacaagcc
tgcatgaagtccattgagattaagcatgctggcgtctctgctgagctgcacagtaacatg
gagatggcagtggatgggagactggtccttgccccgtacgttggtgaaaacatggaagtc
agcatctacggcgctatcatgtatgaagtcaggtttacccatcttggccacatcctcaca
tacacgccacaaaacaacgagttccaactgcagcttagccccaagacctttgcttcgaag
atgcatggtctttgcggaatctgtgatgaaaacggggccaatgacttcacgttgcgagat
ggcacggtcaccacagactggaaaaggcttgtccaggaatggacggtgcagcagccaggg
tacacatgccaggctgttcccgaggagcagtgtcccgtctctgacagctcccactgccag
gtcctcctctcagcgtcgtttgctgaatgccacaaggtcatcgctccagccacattccat
accatctgccagcaagacagttgccaccaggagcgagtgtgtgaggtgattgcttcttac
gcccatctctgtcggaccagtggggtctgtgttgattggaggacaactgatttctgtgct
atgtcatgcccaccgtccctggtgtataaccactgtgagcgtggctgccctcggcactgc
gatgggaacactagcttctgtggggaccatccctcagaaggctgcttctgtccccaacac
caagtttttctggaaggcagctgtgtccccgaggaggcctgcactcagtgtgttggcgag
gatggagttcgacatcagttcctggagacctgggtcccagaccatcagccctgtcagatc
tgtatgtgcctcagtgggagaaagattaactgcactgcccagccgtgtcccacagcccga
gctcccacgtgtggcccatgtgaagtggctcgcctcaagcagagcacaaacctgtgctgc
ccagagtatgagtgtgtgtgtgacctgttcaactgcaacttgcctccagtgcctccgtgt
gaaggagggctccagccaaccctgaccaaccctggagaatgcagacccacctttacctgt
gcctgcaggaaagaagagtgcaaaagagtgtccccaccctcctgcccccctcaccggaca
cccactctccggaagacccagtgctgtgatgaatacgagtgtgcttgcagctgtgtcaac
tccacgctgagctgcccacttggctacctggcctcagccactaccaatgactgtggctgc
accacgaccacctgtctccctgacaaggtttgtgtccaccgaggcaccgtctaccctgtg
ggccagttctgggaggagggctgtgacacgtgcacctgtacggacatggaggatactgtc
gtgggcctgcgtgtggtccagtgctctcaaaggccctgtgaagacagctgtcagccaggt
ttttcttatgttctccacgaaggcgagtgctgtggaaggtgcctgccctctgcttgcaag
gtggtggctggctcactgcggggcgattcccactcttcctggaaaagtgttggatctcgg
tgggctgttcctgagaacccctgcctcgtcaacgagtgtgtccgcgtggaggatgcagtg
tttgtgcagcagaggaacatctcctgcccacagctggctgtccctacctgtcccacaggc
ttccaactgaactgtgagacctcagagtgctgtcctagctgccactgtgagcctgtggag
gcctgcctgctcaatggcaccatcattgggcccgggaagagtgtgatggttgacctatgc
acgacctgccgctgcatcgtgcagacagacgccatctccagattcaagctggagtgcagg
aagactacctgtgaggcctgccccatgggctatcgggaagagaagagccagggtgaatgc
tgtgggagatgcttgcctacagcttgcactattcagctaagaggaggacggatcatgacc
ctgaagcaagatgagacattccaggatggctgtgacagtcatttgtgcagggtcaacgag
agaggagagtacatctgggagaagagggtcacgggctgcccaccatttgatgaacacaag
tgtctggctgaaggaggcaaaatcgtgaaaattccaggcacctgctgtgacacatgtgag
gagcctgattgcaaagacatcacagccaaggtgcagtacatcaaagtgggagattgtaag
tcccaagaggaagtggacattcattactgccagggaaagtgtgccagcaaagctgtgtac
tccattgacatcgaggatgtgcaggagcaatgctcctgctgcctgccctcgaggacggag
cccatgcgcgtgcccttgcactgcaccaatggctctgtcgtgtaccacgaggtcatcaac
gccatgcagtgcaggtgttctccccggaactgcagcaagtga

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (14)   
   UniGene (1)   
   ENSEMBL-MMU (1)   
   MGI-MMU (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (45)   
   RefSeq(nuc) (1)   
   GenBank (22)   
   EMBL (22)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (80)   

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