KEGG   Mus musculus (mouse): 224105Help
Entry
224105            CDS       T01002                                 

Gene name
Pak2, 5330420P17Rik, A130002K10Rik, AI836325, D16Ertd269e, PAK-2, mKIAA4182
Definition
p21 protein (Cdc42/Rac)-activated kinase 2 (EC:2.7.11.1)
Orthology
K04410  
p21-activated kinase 2 [EC:2.7.11.1]
Organism
mmu  Mus musculus (mouse)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Axon guidance
Focal adhesion
T cell receptor signaling pathway
Regulation of actin cytoskeleton
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    224105 (Pak2)
   04010 MAPK signaling pathway
    224105 (Pak2)
   04012 ErbB signaling pathway
    224105 (Pak2)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    224105 (Pak2)
  Cellular commiunity
   04510 Focal adhesion
    224105 (Pak2)
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    224105 (Pak2)
  Development
   04360 Axon guidance
    224105 (Pak2)
 Human Diseases
  Cancers
   05211 Renal cell carcinoma
    224105 (Pak2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     224105 (Pak2)
Protein kinases [BR:mmu01001]
 Serine/threonine protein kinases: STE group
  STE20 family
   224105 (Pak2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
16 B2; 16 22.4 cM
AA seq 524 aa AA seqDB search
MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRNKIISIFSGT
EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP
QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNTKGSETSAVVTEEDDDDEDAAP
PVIAPRPDHTKSIYTRSVIDPIPAPVGDSNVDSGAKSSDKQKKKAKMTDEEIMEKLRTIV
SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE
LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH
ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC
LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAMKSNR
NT seq 1575 nt NT seq  +upstreamnt  +downstreamnt
atgtctgataacggagagctagaagacaagcccccagcacctccagttcggatgagcagt
accatttttagcaccggaggaaaagatcctttatcagccaatcacagtttgaaacctttg
ccttctgttccagaggaaaaaaaacccaggaacaaaatcatctccatattctctggcaca
gaaaaaggaagtaaaaagaaagaaaaagaacggccagagatttctcccccatctgatttt
gagcacaccatccatgttggctttgatgctgttacgggagagttcactggcatgccagaa
cagtgggcgcggctgttgcagacctccaacattaccaaactcgagcagaagaagaaccct
caggcagtgctggatgtcttgaagttctacgactccaacactgtgaaacagaagtacctg
agtttcactcctcctgagaaagatggcttcccttctggaacaccagcactgaacaccaag
gggtcagagacatcagctgtagtgacagaggaagatgatgatgatgaagacgctgctcct
cccgtcattgcccctcggccagatcatacaaaatcaatttacacacggtctgtcatcgac
cccattcctgctccagttggtgattctaatgttgacagtggtgccaagtcttcagacaaa
cagaaaaagaaagccaagatgaccgatgaagagattatggagaaattaagaactattgtg
agcataggggacccaaagaaaaaatacacaagatatgaaaaaattgggcaaggggcttct
ggaacagtttttactgccactgatgtggccctggggcaagaggttgctatcaagcagatt
aatttacagaaacaaccaaagaaggaattgatcattaatgaaattctggtgatgaaagag
ttaaagaatcccaacatagttaacttcttggacagttacctggtaggagatgagttgttt
gtggtaatggagtacctcgctggtgggtccctcactgatgttgtaacagaaacctgcatg
gacgaagcgcagattgccgccgtgtgcagagagtgtttacaggcgttggagtttttacat
gctaatcaagtgatccacagagacatcaaaagtgacaatgtgcttttgggaatggaaggc
tcagttaaacttactgacttcggcttctgtgcccagatcactcctgaacagagcaaacgc
agtactatggttggaacaccgtactggatggcaccagaggtggtgacacggaaagcctat
ggtcccaaagttgacatatggtctctgggcatcatggctatcgagatggttgaaggagag
cctccatacctcaacgaaaatcctctgcgggcattatacctgatagctacaaatggaact
cctgaacttcagaatccagaaaaactttccccaatatttcgggatttcttaaatcggtgt
ttggaaatggatgtggagaaaaggggttcggccaaggaactgttacagcatcctttcctg
aaactggccaaaccattgtctagcttgacgccactgatcctggcagctaaagaagcaatg
aagagtaaccgctaa

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